WNT9B

 

Full name: Wnt family member 9B Alias Symbol: WNT14B
Type: protein-coding gene Cytoband: 17q21.32
Entrez ID: 7484 HGNC ID: HGNC:12779 Ensembl Gene: ENSG00000158955 OMIM ID: 602864
Drug and gene relationship at DGIdb

 

WNT9B involved pathways:

KEGG pathway Description View
hsa04150mTOR signaling pathway
hsa04310Wnt signaling pathway
hsa04390Hippo signaling pathway
hsa04550Signaling pathways regulating pluripotency of stem cells
hsa04916Melanogenesis
hsa05166HTLV-I infection
hsa05200Pathways in cancer
hsa05205Proteoglycans in cancer
hsa05217Basal cell carcinoma

 

Expression of WNT9B:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 WNT9B 7484 1552973_at 0.0151 0.9635
GSE26886 WNT9B 7484 1552973_at -0.3972 0.0038
GSE45670 WNT9B 7484 1552973_at -0.0356 0.7866
GSE53622 WNT9B 7484 84034 -0.7572 0.0000
GSE53624 WNT9B 7484 84034 -0.7868 0.0000
GSE63941 WNT9B 7484 1552973_at -0.0720 0.7049
GSE77861 WNT9B 7484 1552973_at -0.0968 0.3353
SRP133303 WNT9B 7484 RNAseq -0.0252 0.8657
SRP159526 WNT9B 7484 RNAseq 0.0465 0.9295
SRP193095 WNT9B 7484 RNAseq -0.0643 0.6939
SRP219564 WNT9B 7484 RNAseq 0.3091 0.5365
TCGA WNT9B 7484 RNAseq -0.1700 0.7943

Upregulated datasets: 0; Downregulated datasets: 0.  

 

Survival by WNT9B expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of WNT9B:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 WNT9B 7484 5 2 23
GSE20123 WNT9B 7484 5 2 23
GSE43470 WNT9B 7484 1 2 40
GSE46452 WNT9B 7484 32 0 27
GSE47630 WNT9B 7484 9 0 31
GSE54993 WNT9B 7484 3 4 63
GSE54994 WNT9B 7484 11 5 37
GSE60625 WNT9B 7484 4 0 7
GSE74703 WNT9B 7484 1 1 34
GSE74704 WNT9B 7484 4 1 15
TCGA WNT9B 7484 26 6 64

Total number of gains: 101; Total number of losses: 23; Total Number of normals: 364.  

 

Somatic mutations of WNT9B:

 

Generating mutation plots.

 

Highly correlated genes for WNT9B:

 

Showing top 20/208 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
WNT9BLINC011590.708659303
WNT9BIL17RC0.697923303
WNT9BGPR1730.686107303
WNT9BLINC005270.673338303
WNT9BRPH3A0.672005303
WNT9BLYNX10.66384303
WNT9BPRAMEF100.65254303
WNT9BKRTAP5-80.649879303
WNT9BPLXNB10.64597303
WNT9BYOD10.642567404
WNT9BC6orf2010.641367303
WNT9BCLYBL-AS20.639514303
WNT9BC20orf2020.631887303
WNT9BGAB20.629386404
WNT9BTAGAP0.624607303
WNT9BSOX100.623966303
WNT9BMAPT0.623004303
WNT9BCRIP20.620142303
WNT9BLYPD40.618389605
WNT9BG6PC20.617089303

For details and further investigation, click here