| Full name: YOD1 deubiquitinase | Alias Symbol: DKFZp451J1719|OTUD2|DUBA8 | ||
| Type: protein-coding gene | Cytoband: 1q32.1 | ||
| Entrez ID: 55432 | HGNC ID: HGNC:25035 | Ensembl Gene: ENSG00000180667 | OMIM ID: 612023 |
| Drug and gene relationship at DGIdb | |||
Expression of YOD1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | YOD1 | 55432 | 227309_at | -0.9184 | 0.2058 | |
| GSE20347 | YOD1 | 55432 | 215150_at | -1.7599 | 0.0000 | |
| GSE23400 | YOD1 | 55432 | 215150_at | -1.6372 | 0.0000 | |
| GSE26886 | YOD1 | 55432 | 227309_at | -2.5120 | 0.0000 | |
| GSE29001 | YOD1 | 55432 | 215150_at | -2.2239 | 0.0000 | |
| GSE38129 | YOD1 | 55432 | 215150_at | -1.4665 | 0.0000 | |
| GSE45670 | YOD1 | 55432 | 227309_at | -1.3539 | 0.0020 | |
| GSE53622 | YOD1 | 55432 | 15175 | -2.5203 | 0.0000 | |
| GSE53624 | YOD1 | 55432 | 15175 | -2.9782 | 0.0000 | |
| GSE63941 | YOD1 | 55432 | 227309_at | 0.0876 | 0.9066 | |
| GSE77861 | YOD1 | 55432 | 227309_at | -2.0694 | 0.0073 | |
| GSE97050 | YOD1 | 55432 | A_32_P178945 | -0.6293 | 0.2874 | |
| SRP007169 | YOD1 | 55432 | RNAseq | -4.0773 | 0.0000 | |
| SRP008496 | YOD1 | 55432 | RNAseq | -3.9913 | 0.0000 | |
| SRP064894 | YOD1 | 55432 | RNAseq | -3.1798 | 0.0000 | |
| SRP133303 | YOD1 | 55432 | RNAseq | -2.8155 | 0.0000 | |
| SRP159526 | YOD1 | 55432 | RNAseq | -1.8002 | 0.0000 | |
| SRP193095 | YOD1 | 55432 | RNAseq | -3.6040 | 0.0000 | |
| SRP219564 | YOD1 | 55432 | RNAseq | -2.1947 | 0.0140 | |
| TCGA | YOD1 | 55432 | RNAseq | -0.1059 | 0.2365 |
Upregulated datasets: 0; Downregulated datasets: 16.
Survival by YOD1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of YOD1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | YOD1 | 55432 | 11 | 0 | 19 | |
| GSE20123 | YOD1 | 55432 | 11 | 0 | 19 | |
| GSE43470 | YOD1 | 55432 | 8 | 0 | 35 | |
| GSE46452 | YOD1 | 55432 | 3 | 1 | 55 | |
| GSE47630 | YOD1 | 55432 | 14 | 0 | 26 | |
| GSE54993 | YOD1 | 55432 | 0 | 6 | 64 | |
| GSE54994 | YOD1 | 55432 | 14 | 0 | 39 | |
| GSE60625 | YOD1 | 55432 | 0 | 0 | 11 | |
| GSE74703 | YOD1 | 55432 | 8 | 0 | 28 | |
| GSE74704 | YOD1 | 55432 | 5 | 0 | 15 | |
| TCGA | YOD1 | 55432 | 45 | 3 | 48 |
Total number of gains: 119; Total number of losses: 10; Total Number of normals: 359.
Somatic mutations of YOD1:
Generating mutation plots.
Highly correlated genes for YOD1:
Showing top 20/1622 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| YOD1 | EPGN | 0.883051 | 3 | 0 | 3 |
| YOD1 | GYS2 | 0.880315 | 10 | 0 | 10 |
| YOD1 | C18orf25 | 0.860509 | 11 | 0 | 11 |
| YOD1 | CYSRT1 | 0.853075 | 6 | 0 | 6 |
| YOD1 | ATG9B | 0.845801 | 7 | 0 | 7 |
| YOD1 | UPK3B | 0.838305 | 3 | 0 | 3 |
| YOD1 | TRIP10 | 0.837789 | 11 | 0 | 11 |
| YOD1 | ENDOU | 0.83717 | 11 | 0 | 11 |
| YOD1 | NIPAL1 | 0.833843 | 3 | 0 | 3 |
| YOD1 | TP53I3 | 0.833642 | 11 | 0 | 11 |
| YOD1 | DUSP5 | 0.832751 | 11 | 0 | 11 |
| YOD1 | FLG | 0.831812 | 11 | 0 | 11 |
| YOD1 | EPS8L1 | 0.830304 | 11 | 0 | 11 |
| YOD1 | RAET1E | 0.825777 | 6 | 0 | 6 |
| YOD1 | EPS8L2 | 0.82446 | 10 | 0 | 10 |
| YOD1 | EHD3 | 0.820804 | 11 | 0 | 11 |
| YOD1 | STRADB | 0.818486 | 7 | 0 | 7 |
| YOD1 | TTC9 | 0.817286 | 11 | 0 | 11 |
| YOD1 | UBL3 | 0.817128 | 11 | 0 | 11 |
| YOD1 | SASH1 | 0.81683 | 11 | 0 | 11 |
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