| Full name: T cell activation RhoGTPase activating protein | Alias Symbol: FLJ32631|IDDM21|ARHGAP47 | ||
| Type: protein-coding gene | Cytoband: 6q25.3 | ||
| Entrez ID: 117289 | HGNC ID: HGNC:15669 | Ensembl Gene: ENSG00000164691 | OMIM ID: 609667 |
| Drug and gene relationship at DGIdb | |||
Expression of TAGAP:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TAGAP | 117289 | 1552541_at | -0.0282 | 0.9367 | |
| GSE26886 | TAGAP | 117289 | 229723_at | -1.3668 | 0.0003 | |
| GSE45670 | TAGAP | 117289 | 1552541_at | 0.0559 | 0.6285 | |
| GSE53622 | TAGAP | 117289 | 173844 | -0.2144 | 0.2885 | |
| GSE53624 | TAGAP | 117289 | 173844 | -0.6427 | 0.0020 | |
| GSE63941 | TAGAP | 117289 | 1552541_at | 0.2803 | 0.1285 | |
| GSE77861 | TAGAP | 117289 | 1552541_at | -0.0727 | 0.5611 | |
| GSE97050 | TAGAP | 117289 | A_24_P354724 | 0.8917 | 0.0620 | |
| SRP007169 | TAGAP | 117289 | RNAseq | -0.0820 | 0.8890 | |
| SRP008496 | TAGAP | 117289 | RNAseq | -0.7781 | 0.0588 | |
| SRP064894 | TAGAP | 117289 | RNAseq | 0.3051 | 0.3268 | |
| SRP133303 | TAGAP | 117289 | RNAseq | 0.0309 | 0.8964 | |
| SRP159526 | TAGAP | 117289 | RNAseq | -0.7122 | 0.4732 | |
| SRP193095 | TAGAP | 117289 | RNAseq | 1.2209 | 0.0000 | |
| SRP219564 | TAGAP | 117289 | RNAseq | 0.8427 | 0.1164 | |
| TCGA | TAGAP | 117289 | RNAseq | -0.1054 | 0.5741 |
Upregulated datasets: 1; Downregulated datasets: 1.
Survival by TAGAP expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TAGAP:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TAGAP | 117289 | 3 | 5 | 22 | |
| GSE20123 | TAGAP | 117289 | 3 | 4 | 23 | |
| GSE43470 | TAGAP | 117289 | 3 | 0 | 40 | |
| GSE46452 | TAGAP | 117289 | 3 | 10 | 46 | |
| GSE47630 | TAGAP | 117289 | 9 | 4 | 27 | |
| GSE54993 | TAGAP | 117289 | 3 | 2 | 65 | |
| GSE54994 | TAGAP | 117289 | 8 | 8 | 37 | |
| GSE60625 | TAGAP | 117289 | 0 | 1 | 10 | |
| GSE74703 | TAGAP | 117289 | 3 | 0 | 33 | |
| GSE74704 | TAGAP | 117289 | 1 | 2 | 17 | |
| TCGA | TAGAP | 117289 | 13 | 22 | 61 |
Total number of gains: 49; Total number of losses: 58; Total Number of normals: 381.
Somatic mutations of TAGAP:
Generating mutation plots.
Highly correlated genes for TAGAP:
Showing top 20/440 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TAGAP | BIN2 | 0.86851 | 4 | 0 | 4 |
| TAGAP | NCKAP1L | 0.835874 | 5 | 0 | 5 |
| TAGAP | TNFSF8 | 0.830235 | 4 | 0 | 4 |
| TAGAP | LITAF | 0.802092 | 3 | 0 | 3 |
| TAGAP | DPEP2 | 0.795348 | 4 | 0 | 4 |
| TAGAP | CD37 | 0.794835 | 5 | 0 | 5 |
| TAGAP | CD79B | 0.788401 | 5 | 0 | 5 |
| TAGAP | ITGB3 | 0.787325 | 3 | 0 | 3 |
| TAGAP | GIMAP5 | 0.787065 | 3 | 0 | 3 |
| TAGAP | GPR183 | 0.780294 | 4 | 0 | 4 |
| TAGAP | C19orf38 | 0.77556 | 3 | 0 | 3 |
| TAGAP | ARHGAP15 | 0.774646 | 3 | 0 | 3 |
| TAGAP | IRF8 | 0.76763 | 6 | 0 | 5 |
| TAGAP | GPR171 | 0.765297 | 5 | 0 | 5 |
| TAGAP | RHOH | 0.763051 | 5 | 0 | 4 |
| TAGAP | SNAI3 | 0.761678 | 3 | 0 | 3 |
| TAGAP | CORO1A | 0.75869 | 6 | 0 | 6 |
| TAGAP | TRAT1 | 0.757512 | 4 | 0 | 4 |
| TAGAP | CXCR5 | 0.755286 | 3 | 0 | 3 |
| TAGAP | ITK | 0.752908 | 5 | 0 | 5 |
For details and further investigation, click here
