| Full name: YY1 associated protein 1 | Alias Symbol: YY1AP|HCCA2|YAP | ||
| Type: protein-coding gene | Cytoband: 1q22 | ||
| Entrez ID: 55249 | HGNC ID: HGNC:30935 | Ensembl Gene: ENSG00000163374 | OMIM ID: 607860 |
| Drug and gene relationship at DGIdb | |||
Expression of YY1AP1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | YY1AP1 | 55249 | 217836_s_at | -0.0257 | 0.9640 | |
| GSE20347 | YY1AP1 | 55249 | 217836_s_at | -0.2809 | 0.0104 | |
| GSE23400 | YY1AP1 | 55249 | 217836_s_at | -0.2086 | 0.0007 | |
| GSE26886 | YY1AP1 | 55249 | 217836_s_at | 0.4277 | 0.1802 | |
| GSE29001 | YY1AP1 | 55249 | 217836_s_at | -0.3920 | 0.3305 | |
| GSE38129 | YY1AP1 | 55249 | 217836_s_at | -0.1512 | 0.1497 | |
| GSE45670 | YY1AP1 | 55249 | 217836_s_at | -0.4115 | 0.0003 | |
| GSE53622 | YY1AP1 | 55249 | 15084 | -2.4349 | 0.0000 | |
| GSE53624 | YY1AP1 | 55249 | 15084 | -2.9573 | 0.0000 | |
| GSE63941 | YY1AP1 | 55249 | 217836_s_at | 0.7793 | 0.0060 | |
| GSE77861 | YY1AP1 | 55249 | 217836_s_at | -0.0074 | 0.9773 | |
| GSE97050 | YY1AP1 | 55249 | A_33_P3266350 | -1.3212 | 0.1033 | |
| SRP007169 | YY1AP1 | 55249 | RNAseq | -1.3355 | 0.0007 | |
| SRP008496 | YY1AP1 | 55249 | RNAseq | -0.9247 | 0.0002 | |
| SRP064894 | YY1AP1 | 55249 | RNAseq | -0.5084 | 0.0002 | |
| SRP133303 | YY1AP1 | 55249 | RNAseq | -0.2835 | 0.0242 | |
| SRP159526 | YY1AP1 | 55249 | RNAseq | 0.2963 | 0.2995 | |
| SRP193095 | YY1AP1 | 55249 | RNAseq | -0.3875 | 0.0002 | |
| SRP219564 | YY1AP1 | 55249 | RNAseq | -0.2969 | 0.3046 | |
| TCGA | YY1AP1 | 55249 | RNAseq | 0.0041 | 0.9248 |
Upregulated datasets: 0; Downregulated datasets: 3.
Survival by YY1AP1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of YY1AP1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | YY1AP1 | 55249 | 14 | 0 | 16 | |
| GSE20123 | YY1AP1 | 55249 | 13 | 0 | 17 | |
| GSE43470 | YY1AP1 | 55249 | 7 | 2 | 34 | |
| GSE46452 | YY1AP1 | 55249 | 2 | 1 | 56 | |
| GSE47630 | YY1AP1 | 55249 | 14 | 0 | 26 | |
| GSE54993 | YY1AP1 | 55249 | 0 | 5 | 65 | |
| GSE54994 | YY1AP1 | 55249 | 16 | 0 | 37 | |
| GSE60625 | YY1AP1 | 55249 | 0 | 0 | 11 | |
| GSE74703 | YY1AP1 | 55249 | 7 | 2 | 27 | |
| GSE74704 | YY1AP1 | 55249 | 6 | 0 | 14 | |
| TCGA | YY1AP1 | 55249 | 38 | 3 | 55 |
Total number of gains: 117; Total number of losses: 13; Total Number of normals: 358.
Somatic mutations of YY1AP1:
Generating mutation plots.
Highly correlated genes for YY1AP1:
Showing top 20/520 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| YY1AP1 | SMIM5 | 0.840833 | 3 | 0 | 3 |
| YY1AP1 | CYSRT1 | 0.831526 | 3 | 0 | 3 |
| YY1AP1 | FAM214A | 0.792518 | 3 | 0 | 3 |
| YY1AP1 | SH3BGRL2 | 0.790811 | 4 | 0 | 4 |
| YY1AP1 | FCHO2 | 0.784725 | 4 | 0 | 4 |
| YY1AP1 | TMPRSS11B | 0.782327 | 4 | 0 | 4 |
| YY1AP1 | HCG22 | 0.781727 | 4 | 0 | 4 |
| YY1AP1 | IL12A-AS1 | 0.774643 | 3 | 0 | 3 |
| YY1AP1 | TRMT10B | 0.774429 | 3 | 0 | 3 |
| YY1AP1 | SAMD5 | 0.763702 | 4 | 0 | 4 |
| YY1AP1 | C1orf87 | 0.761864 | 3 | 0 | 3 |
| YY1AP1 | IKZF2 | 0.745324 | 4 | 0 | 4 |
| YY1AP1 | KRT32 | 0.744386 | 3 | 0 | 3 |
| YY1AP1 | FAM3B | 0.742271 | 3 | 0 | 3 |
| YY1AP1 | ACER1 | 0.736599 | 3 | 0 | 3 |
| YY1AP1 | ASPG | 0.730963 | 4 | 0 | 4 |
| YY1AP1 | LINC00330 | 0.722353 | 3 | 0 | 3 |
| YY1AP1 | VSIG10L | 0.708461 | 4 | 0 | 3 |
| YY1AP1 | MCEE | 0.706731 | 4 | 0 | 4 |
| YY1AP1 | TMPRSS11A | 0.706671 | 3 | 0 | 3 |
For details and further investigation, click here
