| Full name: methylmalonyl-CoA epimerase | Alias Symbol: GLOD2 | ||
| Type: protein-coding gene | Cytoband: 2p13.3 | ||
| Entrez ID: 84693 | HGNC ID: HGNC:16732 | Ensembl Gene: ENSG00000124370 | OMIM ID: 608419 |
| Drug and gene relationship at DGIdb | |||
Expression of MCEE:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MCEE | 84693 | 226238_at | -0.7353 | 0.1113 | |
| GSE26886 | MCEE | 84693 | 226238_at | -1.5342 | 0.0000 | |
| GSE45670 | MCEE | 84693 | 226238_at | -0.4443 | 0.0191 | |
| GSE53622 | MCEE | 84693 | 34327 | -1.2051 | 0.0000 | |
| GSE53624 | MCEE | 84693 | 34327 | -1.1139 | 0.0000 | |
| GSE63941 | MCEE | 84693 | 226238_at | 0.0672 | 0.9189 | |
| GSE77861 | MCEE | 84693 | 226238_at | -1.1441 | 0.0009 | |
| GSE97050 | MCEE | 84693 | A_23_P56654 | -0.3327 | 0.1934 | |
| SRP007169 | MCEE | 84693 | RNAseq | -1.5984 | 0.0003 | |
| SRP064894 | MCEE | 84693 | RNAseq | -0.7196 | 0.0001 | |
| SRP133303 | MCEE | 84693 | RNAseq | -0.5425 | 0.0078 | |
| SRP159526 | MCEE | 84693 | RNAseq | -1.1430 | 0.0001 | |
| SRP193095 | MCEE | 84693 | RNAseq | -1.0602 | 0.0000 | |
| SRP219564 | MCEE | 84693 | RNAseq | -0.8274 | 0.0518 | |
| TCGA | MCEE | 84693 | RNAseq | -0.3950 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 7.
Survival by MCEE expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MCEE:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MCEE | 84693 | 11 | 1 | 18 | |
| GSE20123 | MCEE | 84693 | 11 | 1 | 18 | |
| GSE43470 | MCEE | 84693 | 3 | 0 | 40 | |
| GSE46452 | MCEE | 84693 | 2 | 3 | 54 | |
| GSE47630 | MCEE | 84693 | 7 | 0 | 33 | |
| GSE54993 | MCEE | 84693 | 0 | 6 | 64 | |
| GSE54994 | MCEE | 84693 | 11 | 0 | 42 | |
| GSE60625 | MCEE | 84693 | 0 | 3 | 8 | |
| GSE74703 | MCEE | 84693 | 3 | 0 | 33 | |
| GSE74704 | MCEE | 84693 | 9 | 0 | 11 | |
| TCGA | MCEE | 84693 | 37 | 2 | 57 |
Total number of gains: 94; Total number of losses: 16; Total Number of normals: 378.
Somatic mutations of MCEE:
Generating mutation plots.
Highly correlated genes for MCEE:
Showing top 20/1550 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MCEE | SASH1 | 0.816905 | 7 | 0 | 7 |
| MCEE | ENDOU | 0.809332 | 7 | 0 | 7 |
| MCEE | SH3PXD2A-AS1 | 0.805152 | 4 | 0 | 4 |
| MCEE | PRSS27 | 0.79111 | 6 | 0 | 6 |
| MCEE | GBP6 | 0.788287 | 4 | 0 | 4 |
| MCEE | ABLIM1 | 0.785899 | 7 | 0 | 7 |
| MCEE | A2ML1 | 0.78561 | 7 | 0 | 7 |
| MCEE | EPHX2 | 0.783832 | 6 | 0 | 6 |
| MCEE | ANXA9 | 0.77723 | 7 | 0 | 7 |
| MCEE | SPAG17 | 0.776694 | 5 | 0 | 5 |
| MCEE | TMED3 | 0.77641 | 6 | 0 | 6 |
| MCEE | SPNS2 | 0.771603 | 5 | 0 | 5 |
| MCEE | MPP7 | 0.771568 | 7 | 0 | 7 |
| MCEE | TTC9 | 0.77098 | 7 | 0 | 7 |
| MCEE | SCP2 | 0.768975 | 7 | 0 | 7 |
| MCEE | CYSRT1 | 0.768333 | 6 | 0 | 6 |
| MCEE | CLIC3 | 0.766642 | 5 | 0 | 5 |
| MCEE | EHD3 | 0.765878 | 7 | 0 | 7 |
| MCEE | NAGK | 0.763631 | 8 | 0 | 7 |
| MCEE | PRSS2 | 0.763107 | 4 | 0 | 3 |
For details and further investigation, click here
