| Full name: sprouty RTK signaling antagonist 3 | Alias Symbol: HSPRY3 | ||
| Type: protein-coding gene | Cytoband: Xq28 and Yq12 | ||
| Entrez ID: 10251 | HGNC ID: HGNC:11271 | Ensembl Gene: ENSG00000168939 | OMIM ID: 300531 |
| Drug and gene relationship at DGIdb | |||
Expression of SPRY3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SPRY3 | 10251 | 232157_at | -0.2053 | 0.2982 | |
| GSE26886 | SPRY3 | 10251 | 232157_at | -0.0958 | 0.3974 | |
| GSE45670 | SPRY3 | 10251 | 232157_at | -0.0521 | 0.6438 | |
| GSE63941 | SPRY3 | 10251 | 232157_at | -0.1321 | 0.3970 | |
| GSE77861 | SPRY3 | 10251 | 232157_at | -0.0478 | 0.6341 | |
| GSE97050 | SPRY3 | 10251 | A_24_P204819 | -0.0551 | 0.8456 | |
| SRP064894 | SPRY3 | 10251 | RNAseq | 0.2466 | 0.4186 | |
| SRP133303 | SPRY3 | 10251 | RNAseq | -0.0556 | 0.8474 | |
| SRP159526 | SPRY3 | 10251 | RNAseq | -1.1716 | 0.0004 | |
| SRP193095 | SPRY3 | 10251 | RNAseq | -0.3839 | 0.0105 | |
| SRP219564 | SPRY3 | 10251 | RNAseq | -0.1142 | 0.7792 | |
| TCGA | SPRY3 | 10251 | RNAseq | -0.2388 | 0.1265 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by SPRY3 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of SPRY3:
No record found for this gene.
Somatic mutations of SPRY3:
Generating mutation plots.
Highly correlated genes for SPRY3:
Showing top 20/26 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SPRY3 | SPTBN4 | 0.835884 | 3 | 0 | 3 |
| SPRY3 | ENPP1 | 0.739 | 3 | 0 | 3 |
| SPRY3 | GARNL3 | 0.699866 | 3 | 0 | 3 |
| SPRY3 | PPM1N | 0.697668 | 3 | 0 | 3 |
| SPRY3 | INSL3 | 0.676736 | 3 | 0 | 3 |
| SPRY3 | SP7 | 0.671966 | 3 | 0 | 3 |
| SPRY3 | GFRA2 | 0.664403 | 3 | 0 | 3 |
| SPRY3 | PRRT2 | 0.656017 | 3 | 0 | 3 |
| SPRY3 | NISCH | 0.652394 | 4 | 0 | 3 |
| SPRY3 | SLC48A1 | 0.647449 | 3 | 0 | 3 |
| SPRY3 | RIIAD1 | 0.645104 | 4 | 0 | 3 |
| SPRY3 | ZADH2 | 0.617325 | 3 | 0 | 3 |
| SPRY3 | CNTN4 | 0.608328 | 4 | 0 | 3 |
| SPRY3 | CD200R1 | 0.60828 | 3 | 0 | 3 |
| SPRY3 | MASP2 | 0.600912 | 4 | 0 | 3 |
| SPRY3 | FAM189A2 | 0.597206 | 4 | 0 | 3 |
| SPRY3 | NPR1 | 0.596651 | 3 | 0 | 3 |
| SPRY3 | HNF1B | 0.578706 | 4 | 0 | 3 |
| SPRY3 | A1CF | 0.57719 | 4 | 0 | 3 |
| SPRY3 | KCNH1 | 0.572684 | 4 | 0 | 4 |
For details and further investigation, click here
