| Full name: ATPase phospholipid transporting 8A1 | Alias Symbol: ATPIA | ||
| Type: protein-coding gene | Cytoband: 4p13 | ||
| Entrez ID: 10396 | HGNC ID: HGNC:13531 | Ensembl Gene: ENSG00000124406 | OMIM ID: 609542 |
| Drug and gene relationship at DGIdb | |||
Expression of ATP8A1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ATP8A1 | 10396 | 213106_at | -0.5018 | 0.6753 | |
| GSE20347 | ATP8A1 | 10396 | 213106_at | -1.1651 | 0.0000 | |
| GSE23400 | ATP8A1 | 10396 | 213106_at | -0.2804 | 0.0001 | |
| GSE26886 | ATP8A1 | 10396 | 213106_at | -1.0425 | 0.0112 | |
| GSE29001 | ATP8A1 | 10396 | 213106_at | -1.0528 | 0.0062 | |
| GSE38129 | ATP8A1 | 10396 | 213106_at | -1.4405 | 0.0000 | |
| GSE45670 | ATP8A1 | 10396 | 213106_at | -1.5253 | 0.0007 | |
| GSE53622 | ATP8A1 | 10396 | 123601 | -1.4360 | 0.0000 | |
| GSE53624 | ATP8A1 | 10396 | 123601 | -1.6564 | 0.0000 | |
| GSE63941 | ATP8A1 | 10396 | 213106_at | -1.3088 | 0.0921 | |
| GSE77861 | ATP8A1 | 10396 | 210192_at | -0.2839 | 0.0015 | |
| GSE97050 | ATP8A1 | 10396 | A_33_P3330952 | -0.2410 | 0.3386 | |
| SRP007169 | ATP8A1 | 10396 | RNAseq | -0.6428 | 0.1712 | |
| SRP064894 | ATP8A1 | 10396 | RNAseq | -0.8089 | 0.0351 | |
| SRP133303 | ATP8A1 | 10396 | RNAseq | -1.0814 | 0.0001 | |
| SRP159526 | ATP8A1 | 10396 | RNAseq | -0.6315 | 0.2635 | |
| SRP193095 | ATP8A1 | 10396 | RNAseq | -1.3578 | 0.0000 | |
| SRP219564 | ATP8A1 | 10396 | RNAseq | -0.7082 | 0.0386 | |
| TCGA | ATP8A1 | 10396 | RNAseq | -1.2261 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 10.
Survival by ATP8A1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ATP8A1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ATP8A1 | 10396 | 0 | 16 | 14 | |
| GSE20123 | ATP8A1 | 10396 | 0 | 16 | 14 | |
| GSE43470 | ATP8A1 | 10396 | 0 | 14 | 29 | |
| GSE46452 | ATP8A1 | 10396 | 1 | 36 | 22 | |
| GSE47630 | ATP8A1 | 10396 | 1 | 18 | 21 | |
| GSE54993 | ATP8A1 | 10396 | 7 | 0 | 63 | |
| GSE54994 | ATP8A1 | 10396 | 4 | 9 | 40 | |
| GSE60625 | ATP8A1 | 10396 | 0 | 0 | 11 | |
| GSE74703 | ATP8A1 | 10396 | 0 | 12 | 24 | |
| GSE74704 | ATP8A1 | 10396 | 0 | 9 | 11 | |
| TCGA | ATP8A1 | 10396 | 12 | 41 | 43 |
Total number of gains: 25; Total number of losses: 171; Total Number of normals: 292.
Somatic mutations of ATP8A1:
Generating mutation plots.
Highly correlated genes for ATP8A1:
Showing top 20/1058 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ATP8A1 | ITM2A | 0.773491 | 10 | 0 | 10 |
| ATP8A1 | CLEC3B | 0.741983 | 3 | 0 | 3 |
| ATP8A1 | CCL14 | 0.739871 | 3 | 0 | 3 |
| ATP8A1 | CYP21A2 | 0.710248 | 3 | 0 | 3 |
| ATP8A1 | SVIP | 0.707053 | 7 | 0 | 6 |
| ATP8A1 | ALOX5 | 0.704789 | 7 | 0 | 7 |
| ATP8A1 | PPM1K | 0.694023 | 7 | 0 | 7 |
| ATP8A1 | GIMAP7 | 0.693079 | 6 | 0 | 4 |
| ATP8A1 | PPM1M | 0.691809 | 7 | 0 | 6 |
| ATP8A1 | HCG27 | 0.688306 | 3 | 0 | 3 |
| ATP8A1 | STT3B | 0.688033 | 3 | 0 | 3 |
| ATP8A1 | ACKR1 | 0.687413 | 8 | 0 | 8 |
| ATP8A1 | AK9 | 0.681489 | 5 | 0 | 5 |
| ATP8A1 | PCGF5 | 0.681268 | 5 | 0 | 5 |
| ATP8A1 | KCNT2 | 0.679083 | 6 | 0 | 6 |
| ATP8A1 | CEP44 | 0.678907 | 3 | 0 | 3 |
| ATP8A1 | EIF4E3 | 0.676984 | 7 | 0 | 6 |
| ATP8A1 | GAB3 | 0.676125 | 6 | 0 | 6 |
| ATP8A1 | TCAIM | 0.67145 | 5 | 0 | 4 |
| ATP8A1 | DOCK8 | 0.669967 | 6 | 0 | 5 |
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