RNF20

 

Full name: ring finger protein 20 Alias Symbol: FLJ20382|FLJ11189|KAIA2779|BRE1A|hBRE1|BRE1
Type: protein-coding gene Cytoband: 9q31.1
Entrez ID: 56254 HGNC ID: HGNC:10062 Ensembl Gene: ENSG00000155827 OMIM ID: 607699
Drug and gene relationship at DGIdb
Screen Evidence:

 

Expression of RNF20:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 RNF20 56254 222683_at -0.2188 0.5389
GSE26886 RNF20 56254 222683_at -0.2514 0.4371
GSE45670 RNF20 56254 222683_at -0.0582 0.6954
GSE53622 RNF20 56254 8471 -0.2437 0.0000
GSE53624 RNF20 56254 8471 -0.1957 0.0000
GSE63941 RNF20 56254 222683_at -0.0532 0.8886
GSE77861 RNF20 56254 222683_at -0.0159 0.9546
GSE97050 RNF20 56254 A_24_P98385 -0.1824 0.3716
SRP007169 RNF20 56254 RNAseq 0.1372 0.7096
SRP008496 RNF20 56254 RNAseq 0.0505 0.8118
SRP064894 RNF20 56254 RNAseq -0.2210 0.0974
SRP133303 RNF20 56254 RNAseq -0.2006 0.1310
SRP159526 RNF20 56254 RNAseq -0.2295 0.2878
SRP193095 RNF20 56254 RNAseq -0.2989 0.0177
SRP219564 RNF20 56254 RNAseq -0.4803 0.0358
TCGA RNF20 56254 RNAseq -0.0050 0.9135

Upregulated datasets: 0; Downregulated datasets: 0.  


 

Survival by RNF20 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of RNF20:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 RNF20 56254 4 10 16
GSE20123 RNF20 56254 5 9 16
GSE43470 RNF20 56254 6 3 34
GSE46452 RNF20 56254 6 13 40
GSE47630 RNF20 56254 1 17 22
GSE54993 RNF20 56254 3 3 64
GSE54994 RNF20 56254 9 11 33
GSE60625 RNF20 56254 0 0 11
GSE74703 RNF20 56254 5 3 28
GSE74704 RNF20 56254 2 6 12
TCGA RNF20 56254 28 21 47

Total number of gains: 69; Total number of losses: 96; Total Number of normals: 323.  


 

Somatic mutations of RNF20:

 

Generating mutation plots.

 

Highly correlated genes for RNF20:

 

Showing top 20/42 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
RNF20SCAF80.657335403
RNF20ZADH20.646407303
RNF20BTBD100.622193403
RNF20HACE10.617466303
RNF20CREBBP0.604043403
RNF20CTR90.597127303
RNF20SWAP700.595369303
RNF20ZNF1890.593941403
RNF20TRIM20.591881303
RNF20FUBP30.581512403
RNF20ACVR2A0.569275303
RNF20TBC1D130.567615403
RNF20WWP20.567149303
RNF20VAMP70.566597303
RNF20RORA0.564919403
RNF20ZFP370.563239403
RNF20CBLL10.562934403
RNF20TIMP30.56197303
RNF20GLYR10.55103303
RNF20SPTLC10.546153504

For details and further investigation, click here