| Full name: zinc finger and BTB domain containing 38 | Alias Symbol: FLJ35036|CIBZ|ZNF921|PPP1R171 | ||
| Type: protein-coding gene | Cytoband: 3q23 | ||
| Entrez ID: 253461 | HGNC ID: HGNC:26636 | Ensembl Gene: ENSG00000177311 | OMIM ID: 612218 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of ZBTB38:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZBTB38 | 253461 | 225512_at | 0.1426 | 0.8433 | |
| GSE20347 | ZBTB38 | 253461 | 219221_at | 0.6038 | 0.0060 | |
| GSE23400 | ZBTB38 | 253461 | 219221_at | 0.2283 | 0.0480 | |
| GSE26886 | ZBTB38 | 253461 | 225512_at | 0.4320 | 0.1334 | |
| GSE29001 | ZBTB38 | 253461 | 219221_at | 0.5686 | 0.1956 | |
| GSE38129 | ZBTB38 | 253461 | 219221_at | 0.1939 | 0.4102 | |
| GSE45670 | ZBTB38 | 253461 | 225512_at | -0.2662 | 0.2610 | |
| GSE53622 | ZBTB38 | 253461 | 33372 | -0.4065 | 0.0001 | |
| GSE53624 | ZBTB38 | 253461 | 33372 | -0.2448 | 0.0058 | |
| GSE63941 | ZBTB38 | 253461 | 225512_at | -1.0414 | 0.0493 | |
| GSE77861 | ZBTB38 | 253461 | 225512_at | 1.2746 | 0.0323 | |
| GSE97050 | ZBTB38 | 253461 | A_33_P3341474 | -0.2289 | 0.4014 | |
| SRP007169 | ZBTB38 | 253461 | RNAseq | 1.4857 | 0.0001 | |
| SRP008496 | ZBTB38 | 253461 | RNAseq | 1.5162 | 0.0000 | |
| SRP064894 | ZBTB38 | 253461 | RNAseq | 0.2096 | 0.4164 | |
| SRP133303 | ZBTB38 | 253461 | RNAseq | 0.4048 | 0.0029 | |
| SRP159526 | ZBTB38 | 253461 | RNAseq | 0.4871 | 0.3996 | |
| SRP193095 | ZBTB38 | 253461 | RNAseq | 0.5192 | 0.0079 | |
| SRP219564 | ZBTB38 | 253461 | RNAseq | 0.2391 | 0.6143 | |
| TCGA | ZBTB38 | 253461 | RNAseq | -0.0731 | 0.2859 |
Upregulated datasets: 3; Downregulated datasets: 1.
Survival by ZBTB38 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ZBTB38:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZBTB38 | 253461 | 19 | 0 | 11 | |
| GSE20123 | ZBTB38 | 253461 | 19 | 0 | 11 | |
| GSE43470 | ZBTB38 | 253461 | 22 | 0 | 21 | |
| GSE46452 | ZBTB38 | 253461 | 15 | 4 | 40 | |
| GSE47630 | ZBTB38 | 253461 | 19 | 3 | 18 | |
| GSE54993 | ZBTB38 | 253461 | 1 | 8 | 61 | |
| GSE54994 | ZBTB38 | 253461 | 34 | 1 | 18 | |
| GSE60625 | ZBTB38 | 253461 | 0 | 6 | 5 | |
| GSE74703 | ZBTB38 | 253461 | 19 | 0 | 17 | |
| GSE74704 | ZBTB38 | 253461 | 13 | 0 | 7 | |
| TCGA | ZBTB38 | 253461 | 63 | 4 | 29 |
Total number of gains: 224; Total number of losses: 26; Total Number of normals: 238.
Somatic mutations of ZBTB38:
Generating mutation plots.
Highly correlated genes for ZBTB38:
Showing top 20/508 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZBTB38 | BHLHB9 | 0.731639 | 3 | 0 | 3 |
| ZBTB38 | CD99L2 | 0.730554 | 4 | 0 | 4 |
| ZBTB38 | TCEAL6 | 0.728457 | 3 | 0 | 3 |
| ZBTB38 | TFDP2 | 0.709887 | 3 | 0 | 3 |
| ZBTB38 | TNFSF12 | 0.702004 | 3 | 0 | 3 |
| ZBTB38 | TRIM45 | 0.697215 | 3 | 0 | 3 |
| ZBTB38 | KLHL36 | 0.695359 | 3 | 0 | 3 |
| ZBTB38 | KIF5B | 0.692776 | 3 | 0 | 3 |
| ZBTB38 | TMSB15B | 0.692025 | 3 | 0 | 3 |
| ZBTB38 | NUB1 | 0.690321 | 4 | 0 | 4 |
| ZBTB38 | RHOU | 0.684869 | 5 | 0 | 5 |
| ZBTB38 | TRAK1 | 0.679028 | 3 | 0 | 3 |
| ZBTB38 | SNX18 | 0.677788 | 3 | 0 | 3 |
| ZBTB38 | STAG2 | 0.67677 | 4 | 0 | 4 |
| ZBTB38 | SAE1 | 0.670994 | 4 | 0 | 4 |
| ZBTB38 | KIAA0753 | 0.67031 | 4 | 0 | 3 |
| ZBTB38 | CORO2B | 0.669819 | 5 | 0 | 5 |
| ZBTB38 | SNAPC5 | 0.668235 | 4 | 0 | 3 |
| ZBTB38 | IGFBP5 | 0.665209 | 3 | 0 | 3 |
| ZBTB38 | NR2F1 | 0.663541 | 3 | 0 | 3 |
For details and further investigation, click here
