| Full name: tripartite motif containing 45 | Alias Symbol: FLJ13181|RNF99 | ||
| Type: protein-coding gene | Cytoband: 1p13.1 | ||
| Entrez ID: 80263 | HGNC ID: HGNC:19018 | Ensembl Gene: ENSG00000134253 | OMIM ID: 609318 |
| Drug and gene relationship at DGIdb | |||
Expression of TRIM45:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TRIM45 | 80263 | 242056_at | 0.0740 | 0.9293 | |
| GSE20347 | TRIM45 | 80263 | 219923_at | 0.4922 | 0.0002 | |
| GSE23400 | TRIM45 | 80263 | 219923_at | 0.0961 | 0.0627 | |
| GSE26886 | TRIM45 | 80263 | 219923_at | 0.6815 | 0.0003 | |
| GSE29001 | TRIM45 | 80263 | 219923_at | 0.6721 | 0.0177 | |
| GSE38129 | TRIM45 | 80263 | 219923_at | 0.3844 | 0.0005 | |
| GSE45670 | TRIM45 | 80263 | 219923_at | 0.2686 | 0.1818 | |
| GSE53622 | TRIM45 | 80263 | 70281 | 0.3358 | 0.0134 | |
| GSE53624 | TRIM45 | 80263 | 70281 | 0.7560 | 0.0000 | |
| GSE63941 | TRIM45 | 80263 | 219923_at | 0.8607 | 0.1159 | |
| GSE77861 | TRIM45 | 80263 | 219923_at | 0.1511 | 0.2215 | |
| GSE97050 | TRIM45 | 80263 | A_33_P3234197 | -0.3956 | 0.1453 | |
| SRP007169 | TRIM45 | 80263 | RNAseq | 2.1703 | 0.0009 | |
| SRP064894 | TRIM45 | 80263 | RNAseq | 1.0288 | 0.0002 | |
| SRP133303 | TRIM45 | 80263 | RNAseq | 0.3307 | 0.0935 | |
| SRP159526 | TRIM45 | 80263 | RNAseq | 1.4213 | 0.0088 | |
| SRP193095 | TRIM45 | 80263 | RNAseq | 0.4324 | 0.0201 | |
| SRP219564 | TRIM45 | 80263 | RNAseq | 0.6470 | 0.1558 | |
| TCGA | TRIM45 | 80263 | RNAseq | 0.1124 | 0.3731 |
Upregulated datasets: 3; Downregulated datasets: 0.
Survival by TRIM45 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TRIM45:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TRIM45 | 80263 | 0 | 8 | 22 | |
| GSE20123 | TRIM45 | 80263 | 0 | 8 | 22 | |
| GSE43470 | TRIM45 | 80263 | 0 | 5 | 38 | |
| GSE46452 | TRIM45 | 80263 | 2 | 1 | 56 | |
| GSE47630 | TRIM45 | 80263 | 9 | 5 | 26 | |
| GSE54993 | TRIM45 | 80263 | 0 | 1 | 69 | |
| GSE54994 | TRIM45 | 80263 | 10 | 2 | 41 | |
| GSE60625 | TRIM45 | 80263 | 0 | 0 | 11 | |
| GSE74703 | TRIM45 | 80263 | 0 | 4 | 32 | |
| GSE74704 | TRIM45 | 80263 | 0 | 4 | 16 | |
| TCGA | TRIM45 | 80263 | 15 | 28 | 53 |
Total number of gains: 36; Total number of losses: 66; Total Number of normals: 386.
Somatic mutations of TRIM45:
Generating mutation plots.
Highly correlated genes for TRIM45:
Showing top 20/349 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TRIM45 | ALPK3 | 0.746507 | 3 | 0 | 3 |
| TRIM45 | FAR2 | 0.70538 | 3 | 0 | 3 |
| TRIM45 | ZBTB38 | 0.697215 | 3 | 0 | 3 |
| TRIM45 | GPRC5C | 0.686337 | 3 | 0 | 3 |
| TRIM45 | TUBB2B | 0.685213 | 4 | 0 | 4 |
| TRIM45 | SLN | 0.683161 | 3 | 0 | 3 |
| TRIM45 | MIEN1 | 0.682649 | 3 | 0 | 3 |
| TRIM45 | TUBGCP4 | 0.664256 | 3 | 0 | 3 |
| TRIM45 | SPRY2 | 0.661053 | 4 | 0 | 3 |
| TRIM45 | DHPS | 0.657842 | 5 | 0 | 5 |
| TRIM45 | SAP30L | 0.650679 | 3 | 0 | 3 |
| TRIM45 | ABHD2 | 0.649627 | 4 | 0 | 4 |
| TRIM45 | ZMYM4 | 0.647563 | 5 | 0 | 4 |
| TRIM45 | IFT81 | 0.643455 | 5 | 0 | 4 |
| TRIM45 | SORBS1 | 0.637795 | 3 | 0 | 3 |
| TRIM45 | POLR2J | 0.637207 | 4 | 0 | 3 |
| TRIM45 | DPYSL3 | 0.637164 | 4 | 0 | 3 |
| TRIM45 | TSPYL2 | 0.636423 | 5 | 0 | 3 |
| TRIM45 | NAB2 | 0.634848 | 4 | 0 | 4 |
| TRIM45 | PTDSS2 | 0.632949 | 3 | 0 | 3 |
For details and further investigation, click here
