| Full name: ras homolog family member U | Alias Symbol: WRCH-1|DJ646B12.2|FLJ10616|WRCH1|CDC42L1|hG28K|fJ646B12.2 | ||
| Type: protein-coding gene | Cytoband: 1q42.13 | ||
| Entrez ID: 58480 | HGNC ID: HGNC:17794 | Ensembl Gene: ENSG00000116574 | OMIM ID: 606366 |
| Drug and gene relationship at DGIdb | |||
Expression of RHOU:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RHOU | 58480 | 223168_at | -1.3197 | 0.1651 | |
| GSE26886 | RHOU | 58480 | 223168_at | -0.0153 | 0.9793 | |
| GSE45670 | RHOU | 58480 | 223168_at | -1.3876 | 0.0014 | |
| GSE53622 | RHOU | 58480 | 66850 | -1.1852 | 0.0000 | |
| GSE53624 | RHOU | 58480 | 66850 | -0.8605 | 0.0000 | |
| GSE63941 | RHOU | 58480 | 223168_at | -0.3850 | 0.7553 | |
| GSE77861 | RHOU | 58480 | 223168_at | 0.6489 | 0.1165 | |
| GSE97050 | RHOU | 58480 | A_24_P62530 | -0.7301 | 0.1241 | |
| SRP007169 | RHOU | 58480 | RNAseq | 0.3798 | 0.5067 | |
| SRP008496 | RHOU | 58480 | RNAseq | 0.3676 | 0.3279 | |
| SRP064894 | RHOU | 58480 | RNAseq | -0.3622 | 0.3656 | |
| SRP133303 | RHOU | 58480 | RNAseq | 0.4795 | 0.1486 | |
| SRP159526 | RHOU | 58480 | RNAseq | -0.0375 | 0.9189 | |
| SRP193095 | RHOU | 58480 | RNAseq | -0.5696 | 0.2377 | |
| SRP219564 | RHOU | 58480 | RNAseq | 0.3191 | 0.5788 | |
| TCGA | RHOU | 58480 | RNAseq | -1.0412 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 3.
Survival by RHOU expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RHOU:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RHOU | 58480 | 11 | 0 | 19 | |
| GSE20123 | RHOU | 58480 | 11 | 0 | 19 | |
| GSE43470 | RHOU | 58480 | 8 | 1 | 34 | |
| GSE46452 | RHOU | 58480 | 4 | 2 | 53 | |
| GSE47630 | RHOU | 58480 | 15 | 0 | 25 | |
| GSE54993 | RHOU | 58480 | 0 | 6 | 64 | |
| GSE54994 | RHOU | 58480 | 17 | 0 | 36 | |
| GSE60625 | RHOU | 58480 | 0 | 0 | 11 | |
| GSE74703 | RHOU | 58480 | 8 | 1 | 27 | |
| GSE74704 | RHOU | 58480 | 5 | 0 | 15 | |
| TCGA | RHOU | 58480 | 45 | 2 | 49 |
Total number of gains: 124; Total number of losses: 12; Total Number of normals: 352.
Somatic mutations of RHOU:
Generating mutation plots.
Highly correlated genes for RHOU:
Showing top 20/709 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RHOU | TRAK1 | 0.832063 | 3 | 0 | 3 |
| RHOU | NPY1R | 0.793951 | 3 | 0 | 3 |
| RHOU | RBPJ | 0.78158 | 3 | 0 | 3 |
| RHOU | PARD3B | 0.777331 | 4 | 0 | 4 |
| RHOU | FBLN1 | 0.772608 | 5 | 0 | 5 |
| RHOU | SORCS1 | 0.760745 | 4 | 0 | 4 |
| RHOU | CLEC3B | 0.760379 | 3 | 0 | 3 |
| RHOU | NCAM1 | 0.755629 | 5 | 0 | 5 |
| RHOU | GPS2 | 0.752031 | 3 | 0 | 3 |
| RHOU | TIMP3 | 0.750752 | 4 | 0 | 4 |
| RHOU | PREX2 | 0.749625 | 4 | 0 | 4 |
| RHOU | ANGPTL1 | 0.748983 | 5 | 0 | 5 |
| RHOU | GGA3 | 0.745839 | 3 | 0 | 3 |
| RHOU | PLAC9 | 0.738863 | 4 | 0 | 4 |
| RHOU | LDB3 | 0.738562 | 4 | 0 | 4 |
| RHOU | OGN | 0.738438 | 5 | 0 | 5 |
| RHOU | ANO5 | 0.737723 | 5 | 0 | 5 |
| RHOU | CDKN1C | 0.736176 | 4 | 0 | 4 |
| RHOU | TMOD1 | 0.732741 | 3 | 0 | 3 |
| RHOU | LRFN5 | 0.731825 | 4 | 0 | 4 |
For details and further investigation, click here
