| Full name: nicalin | Alias Symbol: NICALIN|NET59 | ||
| Type: protein-coding gene | Cytoband: 19p13.3 | ||
| Entrez ID: 56926 | HGNC ID: HGNC:26923 | Ensembl Gene: ENSG00000125912 | OMIM ID: 609156 |
| Drug and gene relationship at DGIdb | |||
Expression of NCLN:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NCLN | 56926 | 222206_s_at | 1.0342 | 0.1214 | |
| GSE20347 | NCLN | 56926 | 222206_s_at | 0.4416 | 0.0083 | |
| GSE23400 | NCLN | 56926 | 222206_s_at | 0.4130 | 0.0000 | |
| GSE26886 | NCLN | 56926 | 222206_s_at | 0.7424 | 0.0008 | |
| GSE29001 | NCLN | 56926 | 222206_s_at | 0.1678 | 0.1864 | |
| GSE38129 | NCLN | 56926 | 222206_s_at | 0.6475 | 0.0000 | |
| GSE45670 | NCLN | 56926 | 222206_s_at | 1.0274 | 0.0003 | |
| GSE53622 | NCLN | 56926 | 19291 | 0.5822 | 0.0000 | |
| GSE53624 | NCLN | 56926 | 57372 | 0.9893 | 0.0000 | |
| GSE63941 | NCLN | 56926 | 222206_s_at | -0.4470 | 0.3474 | |
| GSE77861 | NCLN | 56926 | 215857_at | -0.0473 | 0.7335 | |
| GSE97050 | NCLN | 56926 | A_24_P339664 | 0.5877 | 0.1453 | |
| SRP007169 | NCLN | 56926 | RNAseq | 0.9022 | 0.0145 | |
| SRP008496 | NCLN | 56926 | RNAseq | 0.7599 | 0.0026 | |
| SRP064894 | NCLN | 56926 | RNAseq | 1.1628 | 0.0000 | |
| SRP133303 | NCLN | 56926 | RNAseq | 0.9317 | 0.0000 | |
| SRP159526 | NCLN | 56926 | RNAseq | 0.8723 | 0.0000 | |
| SRP193095 | NCLN | 56926 | RNAseq | 0.6701 | 0.0000 | |
| SRP219564 | NCLN | 56926 | RNAseq | 1.0620 | 0.0019 | |
| TCGA | NCLN | 56926 | RNAseq | 0.1362 | 0.0041 |
Upregulated datasets: 3; Downregulated datasets: 0.
Survival by NCLN expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NCLN:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NCLN | 56926 | 4 | 4 | 22 | |
| GSE20123 | NCLN | 56926 | 3 | 4 | 23 | |
| GSE43470 | NCLN | 56926 | 1 | 9 | 33 | |
| GSE46452 | NCLN | 56926 | 47 | 1 | 11 | |
| GSE47630 | NCLN | 56926 | 5 | 7 | 28 | |
| GSE54993 | NCLN | 56926 | 16 | 3 | 51 | |
| GSE54994 | NCLN | 56926 | 8 | 16 | 29 | |
| GSE60625 | NCLN | 56926 | 9 | 0 | 2 | |
| GSE74703 | NCLN | 56926 | 1 | 6 | 29 | |
| GSE74704 | NCLN | 56926 | 1 | 3 | 16 | |
| TCGA | NCLN | 56926 | 8 | 22 | 66 |
Total number of gains: 103; Total number of losses: 75; Total Number of normals: 310.
Somatic mutations of NCLN:
Generating mutation plots.
Highly correlated genes for NCLN:
Showing top 20/1180 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NCLN | MTHFD1L | 0.76271 | 3 | 0 | 3 |
| NCLN | SLC19A1 | 0.759695 | 3 | 0 | 3 |
| NCLN | VMA21 | 0.75341 | 3 | 0 | 3 |
| NCLN | EBNA1BP2 | 0.751814 | 3 | 0 | 3 |
| NCLN | ACY1 | 0.739001 | 3 | 0 | 3 |
| NCLN | CLPTM1L | 0.735502 | 5 | 0 | 5 |
| NCLN | MICALCL | 0.73491 | 5 | 0 | 5 |
| NCLN | ZBTB9 | 0.732867 | 4 | 0 | 4 |
| NCLN | CDC42EP1 | 0.731861 | 3 | 0 | 3 |
| NCLN | WDR54 | 0.731424 | 5 | 0 | 5 |
| NCLN | MRPL47 | 0.72925 | 6 | 0 | 6 |
| NCLN | UBE2J2 | 0.724058 | 3 | 0 | 3 |
| NCLN | DKC1 | 0.721693 | 3 | 0 | 3 |
| NCLN | HM13 | 0.720582 | 3 | 0 | 3 |
| NCLN | FHL3 | 0.719369 | 4 | 0 | 4 |
| NCLN | PSMG3 | 0.718931 | 6 | 0 | 6 |
| NCLN | NAA38 | 0.713191 | 3 | 0 | 3 |
| NCLN | PPP1R9B | 0.711036 | 4 | 0 | 3 |
| NCLN | NACC1 | 0.710741 | 4 | 0 | 3 |
| NCLN | ZNF707 | 0.70992 | 3 | 0 | 3 |
For details and further investigation, click here
