| Full name: RNA pseudouridine synthase domain containing 1 | Alias Symbol: RLUCL|MGC19600 | ||
| Type: protein-coding gene | Cytoband: 16p13.3 | ||
| Entrez ID: 113000 | HGNC ID: HGNC:14173 | Ensembl Gene: ENSG00000007376 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of RPUSD1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RPUSD1 | 113000 | 226078_at | 0.2963 | 0.3017 | |
| GSE26886 | RPUSD1 | 113000 | 226078_at | 0.0685 | 0.6513 | |
| GSE45670 | RPUSD1 | 113000 | 226078_at | 0.1063 | 0.2399 | |
| GSE53622 | RPUSD1 | 113000 | 49836 | -1.0781 | 0.0000 | |
| GSE53624 | RPUSD1 | 113000 | 49836 | -0.3670 | 0.0000 | |
| GSE63941 | RPUSD1 | 113000 | 226078_at | 0.2682 | 0.1470 | |
| GSE77861 | RPUSD1 | 113000 | 226078_at | -0.1070 | 0.5217 | |
| GSE97050 | RPUSD1 | 113000 | A_33_P3382513 | 0.0724 | 0.9046 | |
| SRP007169 | RPUSD1 | 113000 | RNAseq | 0.0858 | 0.8184 | |
| SRP008496 | RPUSD1 | 113000 | RNAseq | -0.0129 | 0.9588 | |
| SRP064894 | RPUSD1 | 113000 | RNAseq | 0.7767 | 0.0090 | |
| SRP133303 | RPUSD1 | 113000 | RNAseq | 0.7269 | 0.0006 | |
| SRP159526 | RPUSD1 | 113000 | RNAseq | 0.4883 | 0.0990 | |
| SRP193095 | RPUSD1 | 113000 | RNAseq | 0.6165 | 0.0000 | |
| SRP219564 | RPUSD1 | 113000 | RNAseq | 0.8745 | 0.0270 | |
| TCGA | RPUSD1 | 113000 | RNAseq | 0.1864 | 0.0044 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by RPUSD1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RPUSD1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RPUSD1 | 113000 | 5 | 5 | 20 | |
| GSE20123 | RPUSD1 | 113000 | 5 | 4 | 21 | |
| GSE43470 | RPUSD1 | 113000 | 4 | 7 | 32 | |
| GSE46452 | RPUSD1 | 113000 | 38 | 1 | 20 | |
| GSE47630 | RPUSD1 | 113000 | 13 | 6 | 21 | |
| GSE54993 | RPUSD1 | 113000 | 3 | 5 | 62 | |
| GSE54994 | RPUSD1 | 113000 | 5 | 9 | 39 | |
| GSE60625 | RPUSD1 | 113000 | 4 | 0 | 7 | |
| GSE74703 | RPUSD1 | 113000 | 4 | 5 | 27 | |
| GSE74704 | RPUSD1 | 113000 | 3 | 2 | 15 | |
| TCGA | RPUSD1 | 113000 | 20 | 14 | 62 |
Total number of gains: 104; Total number of losses: 58; Total Number of normals: 326.
Somatic mutations of RPUSD1:
Generating mutation plots.
Highly correlated genes for RPUSD1:
Showing top 20/190 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RPUSD1 | GNB2 | 0.733055 | 3 | 0 | 3 |
| RPUSD1 | HSD17B8 | 0.711077 | 3 | 0 | 3 |
| RPUSD1 | SLIT1 | 0.710037 | 4 | 0 | 4 |
| RPUSD1 | RABEP2 | 0.701378 | 3 | 0 | 3 |
| RPUSD1 | TSEN54 | 0.693559 | 5 | 0 | 5 |
| RPUSD1 | TUSC2 | 0.688444 | 3 | 0 | 3 |
| RPUSD1 | RHAG | 0.680995 | 3 | 0 | 3 |
| RPUSD1 | SFTPB | 0.670901 | 3 | 0 | 3 |
| RPUSD1 | MYL10 | 0.670756 | 3 | 0 | 3 |
| RPUSD1 | TIMMDC1 | 0.669221 | 4 | 0 | 3 |
| RPUSD1 | PLP2 | 0.667674 | 3 | 0 | 3 |
| RPUSD1 | HSD17B10 | 0.66555 | 3 | 0 | 3 |
| RPUSD1 | GJB1 | 0.664261 | 3 | 0 | 3 |
| RPUSD1 | PRR19 | 0.662963 | 4 | 0 | 3 |
| RPUSD1 | ZFP42 | 0.662503 | 3 | 0 | 3 |
| RPUSD1 | TPRN | 0.662203 | 4 | 0 | 4 |
| RPUSD1 | NBEAL2 | 0.660971 | 3 | 0 | 3 |
| RPUSD1 | APRT | 0.658648 | 3 | 0 | 3 |
| RPUSD1 | LINC00853 | 0.64966 | 4 | 0 | 4 |
| RPUSD1 | DUOX1 | 0.64825 | 3 | 0 | 3 |
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