AMER1

 

Full name: APC membrane recruitment protein 1 Alias Symbol: RP11-403E24.2|FLJ39827|WTX
Type: protein-coding gene Cytoband: Xq11.2
Entrez ID: 139285 HGNC ID: HGNC:26837 Ensembl Gene: ENSG00000184675 OMIM ID: 300647
Drug and gene relationship at DGIdb
Screen Evidence:
  • This gene has been idenfitied as a common driver in this paper.
  • Knocking out of this gene by CRIPR/Cas9 screen found altered tolerance on DNA toxicity in Genotoxic Screens.

 

Expression of AMER1:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 AMER1 139285 1552882_a_at 0.5156 0.1071
GSE26886 AMER1 139285 1552882_a_at -0.2662 0.1447
GSE45670 AMER1 139285 1552882_a_at -0.0394 0.7571
GSE53622 AMER1 139285 25849 -0.3024 0.0355
GSE53624 AMER1 139285 25849 -0.1885 0.0760
GSE63941 AMER1 139285 1552882_a_at 0.1220 0.3433
GSE77861 AMER1 139285 1552882_a_at -0.0673 0.7150
SRP007169 AMER1 139285 RNAseq -0.9010 0.0174
SRP008496 AMER1 139285 RNAseq -0.3505 0.2428
SRP064894 AMER1 139285 RNAseq -0.5204 0.0234
SRP133303 AMER1 139285 RNAseq -0.3748 0.1015
SRP159526 AMER1 139285 RNAseq -0.1634 0.5434
SRP193095 AMER1 139285 RNAseq -0.4813 0.0000
SRP219564 AMER1 139285 RNAseq -0.0808 0.8141

Upregulated datasets: 0; Downregulated datasets: 0.  


 

Survival by AMER1 expression:

 

GSE53622GSE53624

 

Note: Click image to view full size file.  


Copy number change of AMER1:

 

No record found for this gene.


 

Somatic mutations of AMER1:

 

Generating mutation plots.

 

Highly correlated genes for AMER1:

 

Showing top 20/28 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
AMER1ZFP420.738457303
AMER1BAHD10.72989303
AMER1FOXP40.677529303
AMER1ZNF6830.672636303
AMER1FLYWCH20.670397303
AMER1ARX0.657293303
AMER1CYP2F10.653762303
AMER1FOXH10.642593303
AMER1ARPC40.619688303
AMER1ARF30.619044303
AMER1KLK20.61211303
AMER1AKT1S10.608841303
AMER1MXD30.590842303
AMER1GPR260.588683303
AMER1MIF0.583304303
AMER1PNPLA60.582918403
AMER1TOB1-AS10.578633303
AMER1SAFB0.575241303
AMER1GOLT1A0.568792303
AMER1RPUSD10.56794403

For details and further investigation, click here