| Full name: interferon regulatory factor 2 binding protein 1 | Alias Symbol: DKFZP434M154|IRF-2BP1 | ||
| Type: protein-coding gene | Cytoband: 19q13.32 | ||
| Entrez ID: 26145 | HGNC ID: HGNC:21728 | Ensembl Gene: ENSG00000170604 | OMIM ID: 615331 |
| Drug and gene relationship at DGIdb | |||
Expression of IRF2BP1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | IRF2BP1 | 26145 | 213771_at | 0.0749 | 0.7944 | |
| GSE20347 | IRF2BP1 | 26145 | 213771_at | -0.1781 | 0.0129 | |
| GSE23400 | IRF2BP1 | 26145 | 213771_at | -0.0609 | 0.1797 | |
| GSE26886 | IRF2BP1 | 26145 | 213771_at | 0.1147 | 0.4081 | |
| GSE29001 | IRF2BP1 | 26145 | 213771_at | -0.3958 | 0.0252 | |
| GSE38129 | IRF2BP1 | 26145 | 213771_at | -0.2491 | 0.0019 | |
| GSE45670 | IRF2BP1 | 26145 | 213771_at | -0.0940 | 0.3554 | |
| GSE53622 | IRF2BP1 | 26145 | 18741 | 0.0223 | 0.7744 | |
| GSE53624 | IRF2BP1 | 26145 | 18741 | 0.1891 | 0.0160 | |
| GSE63941 | IRF2BP1 | 26145 | 213771_at | 0.7393 | 0.0017 | |
| GSE77861 | IRF2BP1 | 26145 | 213771_at | -0.0246 | 0.8726 | |
| GSE97050 | IRF2BP1 | 26145 | A_33_P3398946 | 0.0807 | 0.8277 | |
| SRP007169 | IRF2BP1 | 26145 | RNAseq | -0.7265 | 0.0614 | |
| SRP008496 | IRF2BP1 | 26145 | RNAseq | -0.2665 | 0.3820 | |
| SRP064894 | IRF2BP1 | 26145 | RNAseq | 0.3432 | 0.2883 | |
| SRP133303 | IRF2BP1 | 26145 | RNAseq | -0.1949 | 0.2312 | |
| SRP159526 | IRF2BP1 | 26145 | RNAseq | 0.8685 | 0.0007 | |
| SRP193095 | IRF2BP1 | 26145 | RNAseq | 0.1253 | 0.4974 | |
| SRP219564 | IRF2BP1 | 26145 | RNAseq | -0.0934 | 0.7790 | |
| TCGA | IRF2BP1 | 26145 | RNAseq | -0.0871 | 0.0835 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by IRF2BP1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of IRF2BP1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | IRF2BP1 | 26145 | 4 | 5 | 21 | |
| GSE20123 | IRF2BP1 | 26145 | 4 | 4 | 22 | |
| GSE43470 | IRF2BP1 | 26145 | 3 | 11 | 29 | |
| GSE46452 | IRF2BP1 | 26145 | 45 | 1 | 13 | |
| GSE47630 | IRF2BP1 | 26145 | 8 | 7 | 25 | |
| GSE54993 | IRF2BP1 | 26145 | 17 | 4 | 49 | |
| GSE54994 | IRF2BP1 | 26145 | 5 | 13 | 35 | |
| GSE60625 | IRF2BP1 | 26145 | 9 | 0 | 2 | |
| GSE74703 | IRF2BP1 | 26145 | 3 | 7 | 26 | |
| GSE74704 | IRF2BP1 | 26145 | 4 | 2 | 14 | |
| TCGA | IRF2BP1 | 26145 | 16 | 15 | 65 |
Total number of gains: 118; Total number of losses: 69; Total Number of normals: 301.
Somatic mutations of IRF2BP1:
Generating mutation plots.
Highly correlated genes for IRF2BP1:
Showing top 20/794 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| IRF2BP1 | TBC1D22A | 0.799559 | 3 | 0 | 3 |
| IRF2BP1 | CNTF | 0.758887 | 3 | 0 | 3 |
| IRF2BP1 | RRNAD1 | 0.746603 | 3 | 0 | 3 |
| IRF2BP1 | CD37 | 0.737248 | 3 | 0 | 3 |
| IRF2BP1 | ADCK1 | 0.730224 | 3 | 0 | 3 |
| IRF2BP1 | DCTN1 | 0.727425 | 4 | 0 | 4 |
| IRF2BP1 | PMF1 | 0.721609 | 5 | 0 | 5 |
| IRF2BP1 | EEFSEC | 0.70994 | 4 | 0 | 4 |
| IRF2BP1 | DTX1 | 0.7098 | 3 | 0 | 3 |
| IRF2BP1 | TRMT2B | 0.709108 | 3 | 0 | 3 |
| IRF2BP1 | CIC | 0.708816 | 3 | 0 | 3 |
| IRF2BP1 | ZFYVE27 | 0.706471 | 3 | 0 | 3 |
| IRF2BP1 | LIPF | 0.704713 | 3 | 0 | 3 |
| IRF2BP1 | SLC25A39 | 0.704341 | 3 | 0 | 3 |
| IRF2BP1 | NPHS2 | 0.703091 | 3 | 0 | 3 |
| IRF2BP1 | ARHGEF16 | 0.701887 | 3 | 0 | 3 |
| IRF2BP1 | SPTAN1 | 0.69788 | 4 | 0 | 4 |
| IRF2BP1 | TBC1D25 | 0.693098 | 3 | 0 | 3 |
| IRF2BP1 | UBE2NL | 0.687111 | 4 | 0 | 3 |
| IRF2BP1 | SLC25A10 | 0.685189 | 4 | 0 | 3 |
For details and further investigation, click here
