| Full name: mitochondrial methionyl-tRNA formyltransferase | Alias Symbol: FMT1 | ||
| Type: protein-coding gene | Cytoband: 15q22.31 | ||
| Entrez ID: 123263 | HGNC ID: HGNC:29666 | Ensembl Gene: ENSG00000103707 | OMIM ID: 611766 |
| Drug and gene relationship at DGIdb | |||
Expression of MTFMT:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MTFMT | 123263 | 235689_at | 0.0915 | 0.9234 | |
| GSE26886 | MTFMT | 123263 | 235689_at | -0.1673 | 0.5593 | |
| GSE45670 | MTFMT | 123263 | 235689_at | 0.0200 | 0.9108 | |
| GSE53622 | MTFMT | 123263 | 123966 | 0.3686 | 0.0000 | |
| GSE53624 | MTFMT | 123263 | 123966 | 0.3093 | 0.0006 | |
| GSE63941 | MTFMT | 123263 | 235689_at | -0.2526 | 0.7113 | |
| GSE77861 | MTFMT | 123263 | 235689_at | 0.2579 | 0.1861 | |
| GSE97050 | MTFMT | 123263 | A_23_P117727 | 0.0226 | 0.9410 | |
| SRP007169 | MTFMT | 123263 | RNAseq | 0.1316 | 0.7623 | |
| SRP008496 | MTFMT | 123263 | RNAseq | 0.3522 | 0.2218 | |
| SRP064894 | MTFMT | 123263 | RNAseq | 0.1438 | 0.1976 | |
| SRP133303 | MTFMT | 123263 | RNAseq | 0.2373 | 0.0045 | |
| SRP159526 | MTFMT | 123263 | RNAseq | 0.2722 | 0.4805 | |
| SRP193095 | MTFMT | 123263 | RNAseq | 0.1065 | 0.1235 | |
| SRP219564 | MTFMT | 123263 | RNAseq | -0.2292 | 0.3697 | |
| TCGA | MTFMT | 123263 | RNAseq | 0.1250 | 0.0646 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by MTFMT expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MTFMT:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MTFMT | 123263 | 7 | 3 | 20 | |
| GSE20123 | MTFMT | 123263 | 7 | 3 | 20 | |
| GSE43470 | MTFMT | 123263 | 4 | 6 | 33 | |
| GSE46452 | MTFMT | 123263 | 3 | 7 | 49 | |
| GSE47630 | MTFMT | 123263 | 8 | 10 | 22 | |
| GSE54993 | MTFMT | 123263 | 5 | 6 | 59 | |
| GSE54994 | MTFMT | 123263 | 6 | 7 | 40 | |
| GSE60625 | MTFMT | 123263 | 4 | 0 | 7 | |
| GSE74703 | MTFMT | 123263 | 4 | 3 | 29 | |
| GSE74704 | MTFMT | 123263 | 3 | 3 | 14 | |
| TCGA | MTFMT | 123263 | 10 | 16 | 70 |
Total number of gains: 61; Total number of losses: 64; Total Number of normals: 363.
Somatic mutations of MTFMT:
Generating mutation plots.
Highly correlated genes for MTFMT:
Showing top 20/435 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MTFMT | ZNF689 | 0.792446 | 3 | 0 | 3 |
| MTFMT | TMEM60 | 0.782634 | 3 | 0 | 3 |
| MTFMT | PLEKHA2 | 0.758522 | 3 | 0 | 3 |
| MTFMT | CNOT7 | 0.75124 | 3 | 0 | 3 |
| MTFMT | IPO7 | 0.741638 | 3 | 0 | 3 |
| MTFMT | MTRF1L | 0.738359 | 3 | 0 | 3 |
| MTFMT | ZFPL1 | 0.737441 | 3 | 0 | 3 |
| MTFMT | CDIPT | 0.736317 | 4 | 0 | 4 |
| MTFMT | SDHAF2 | 0.731003 | 3 | 0 | 3 |
| MTFMT | ADAM9 | 0.724636 | 3 | 0 | 3 |
| MTFMT | FRAT1 | 0.723864 | 3 | 0 | 3 |
| MTFMT | IMMT | 0.723641 | 4 | 0 | 4 |
| MTFMT | RAB34 | 0.719389 | 3 | 0 | 3 |
| MTFMT | MTX2 | 0.718017 | 3 | 0 | 3 |
| MTFMT | MRPL44 | 0.717589 | 3 | 0 | 3 |
| MTFMT | BCCIP | 0.717175 | 3 | 0 | 3 |
| MTFMT | SPATA2 | 0.716958 | 3 | 0 | 3 |
| MTFMT | PJA1 | 0.713262 | 3 | 0 | 3 |
| MTFMT | FAM118B | 0.709937 | 4 | 0 | 3 |
| MTFMT | SMC2 | 0.707302 | 4 | 0 | 4 |
For details and further investigation, click here
