| Full name: zinc finger with KRAB and SCAN domains 1 | Alias Symbol: KOX18|PHZ-37|ZSCAN33 | ||
| Type: protein-coding gene | Cytoband: 7q22.1 | ||
| Entrez ID: 7586 | HGNC ID: HGNC:13101 | Ensembl Gene: ENSG00000106261 | OMIM ID: 601260 |
| Drug and gene relationship at DGIdb | |||
Expression of ZKSCAN1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZKSCAN1 | 7586 | 225221_at | -0.1547 | 0.8083 | |
| GSE20347 | ZKSCAN1 | 7586 | 214670_at | -0.3185 | 0.0817 | |
| GSE23400 | ZKSCAN1 | 7586 | 214670_at | -0.1118 | 0.2067 | |
| GSE26886 | ZKSCAN1 | 7586 | 225221_at | -0.5975 | 0.0632 | |
| GSE29001 | ZKSCAN1 | 7586 | 214670_at | -0.7013 | 0.1178 | |
| GSE38129 | ZKSCAN1 | 7586 | 214670_at | -0.3349 | 0.1830 | |
| GSE45670 | ZKSCAN1 | 7586 | 225221_at | -0.0549 | 0.8026 | |
| GSE53622 | ZKSCAN1 | 7586 | 19423 | -0.1420 | 0.0788 | |
| GSE53624 | ZKSCAN1 | 7586 | 19423 | -0.2847 | 0.0000 | |
| GSE63941 | ZKSCAN1 | 7586 | 225221_at | -1.0353 | 0.0252 | |
| GSE77861 | ZKSCAN1 | 7586 | 225221_at | -0.1290 | 0.7203 | |
| GSE97050 | ZKSCAN1 | 7586 | A_33_P3234667 | -0.1345 | 0.5065 | |
| SRP007169 | ZKSCAN1 | 7586 | RNAseq | -1.5006 | 0.0000 | |
| SRP008496 | ZKSCAN1 | 7586 | RNAseq | -1.0535 | 0.0036 | |
| SRP064894 | ZKSCAN1 | 7586 | RNAseq | -0.5009 | 0.0076 | |
| SRP133303 | ZKSCAN1 | 7586 | RNAseq | -0.3428 | 0.0064 | |
| SRP159526 | ZKSCAN1 | 7586 | RNAseq | -0.6806 | 0.0004 | |
| SRP193095 | ZKSCAN1 | 7586 | RNAseq | -0.3674 | 0.0060 | |
| SRP219564 | ZKSCAN1 | 7586 | RNAseq | -0.2312 | 0.6026 | |
| TCGA | ZKSCAN1 | 7586 | RNAseq | -0.1904 | 0.0013 |
Upregulated datasets: 0; Downregulated datasets: 3.
Survival by ZKSCAN1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ZKSCAN1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZKSCAN1 | 7586 | 13 | 0 | 17 | |
| GSE20123 | ZKSCAN1 | 7586 | 13 | 0 | 17 | |
| GSE43470 | ZKSCAN1 | 7586 | 6 | 2 | 35 | |
| GSE46452 | ZKSCAN1 | 7586 | 11 | 1 | 47 | |
| GSE47630 | ZKSCAN1 | 7586 | 7 | 3 | 30 | |
| GSE54993 | ZKSCAN1 | 7586 | 1 | 9 | 60 | |
| GSE54994 | ZKSCAN1 | 7586 | 16 | 3 | 34 | |
| GSE60625 | ZKSCAN1 | 7586 | 0 | 0 | 11 | |
| GSE74703 | ZKSCAN1 | 7586 | 6 | 1 | 29 | |
| GSE74704 | ZKSCAN1 | 7586 | 9 | 0 | 11 | |
| TCGA | ZKSCAN1 | 7586 | 52 | 6 | 38 |
Total number of gains: 134; Total number of losses: 25; Total Number of normals: 329.
Somatic mutations of ZKSCAN1:
Generating mutation plots.
Highly correlated genes for ZKSCAN1:
Showing top 20/366 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZKSCAN1 | GDPD1 | 0.793581 | 3 | 0 | 3 |
| ZKSCAN1 | UBE2E1 | 0.768017 | 3 | 0 | 3 |
| ZKSCAN1 | DPY19L3 | 0.767444 | 3 | 0 | 3 |
| ZKSCAN1 | ZNF416 | 0.761932 | 3 | 0 | 3 |
| ZKSCAN1 | ZNF566 | 0.75656 | 3 | 0 | 3 |
| ZKSCAN1 | ZNF100 | 0.756053 | 3 | 0 | 3 |
| ZKSCAN1 | ZNF44 | 0.750917 | 3 | 0 | 3 |
| ZKSCAN1 | TTC17 | 0.74912 | 3 | 0 | 3 |
| ZKSCAN1 | MPP5 | 0.747627 | 3 | 0 | 3 |
| ZKSCAN1 | ACTR2 | 0.741285 | 3 | 0 | 3 |
| ZKSCAN1 | WWP1 | 0.738815 | 4 | 0 | 4 |
| ZKSCAN1 | TMEM218 | 0.735779 | 4 | 0 | 3 |
| ZKSCAN1 | GPATCH8 | 0.734669 | 3 | 0 | 3 |
| ZKSCAN1 | PSEN1 | 0.728644 | 4 | 0 | 4 |
| ZKSCAN1 | INTS6 | 0.725984 | 3 | 0 | 3 |
| ZKSCAN1 | TTLL1 | 0.725026 | 3 | 0 | 3 |
| ZKSCAN1 | TOPORS | 0.722284 | 3 | 0 | 3 |
| ZKSCAN1 | BIVM | 0.720518 | 4 | 0 | 4 |
| ZKSCAN1 | MAP4K5 | 0.718399 | 3 | 0 | 3 |
| ZKSCAN1 | SYNRG | 0.71706 | 5 | 0 | 4 |
For details and further investigation, click here
