| Full name: ubiquitin conjugating enzyme E2 E1 | Alias Symbol: UbcH6 | ||
| Type: protein-coding gene | Cytoband: 3p24.2 | ||
| Entrez ID: 7324 | HGNC ID: HGNC:12477 | Ensembl Gene: ENSG00000170142 | OMIM ID: 602916 |
| Drug and gene relationship at DGIdb | |||
Expression of UBE2E1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | UBE2E1 | 7324 | 212519_at | -0.2157 | 0.4515 | |
| GSE20347 | UBE2E1 | 7324 | 212519_at | -0.9804 | 0.0000 | |
| GSE23400 | UBE2E1 | 7324 | 212519_at | -0.4221 | 0.0000 | |
| GSE26886 | UBE2E1 | 7324 | 212519_at | -0.7188 | 0.0001 | |
| GSE29001 | UBE2E1 | 7324 | 212519_at | -1.0140 | 0.0101 | |
| GSE38129 | UBE2E1 | 7324 | 212519_at | -0.5902 | 0.0000 | |
| GSE45670 | UBE2E1 | 7324 | 212519_at | -0.2638 | 0.0453 | |
| GSE53622 | UBE2E1 | 7324 | 119084 | -0.5324 | 0.0000 | |
| GSE53624 | UBE2E1 | 7324 | 119084 | -0.9060 | 0.0000 | |
| GSE63941 | UBE2E1 | 7324 | 212519_at | -0.3229 | 0.5290 | |
| GSE77861 | UBE2E1 | 7324 | 212519_at | -0.8645 | 0.0015 | |
| GSE97050 | UBE2E1 | 7324 | A_23_P6963 | -0.3310 | 0.1581 | |
| SRP007169 | UBE2E1 | 7324 | RNAseq | -2.1266 | 0.0000 | |
| SRP008496 | UBE2E1 | 7324 | RNAseq | -1.6769 | 0.0000 | |
| SRP064894 | UBE2E1 | 7324 | RNAseq | -0.7812 | 0.0000 | |
| SRP133303 | UBE2E1 | 7324 | RNAseq | -0.4740 | 0.0046 | |
| SRP159526 | UBE2E1 | 7324 | RNAseq | -0.8702 | 0.0001 | |
| SRP193095 | UBE2E1 | 7324 | RNAseq | -0.9475 | 0.0000 | |
| SRP219564 | UBE2E1 | 7324 | RNAseq | -0.9869 | 0.0000 | |
| TCGA | UBE2E1 | 7324 | RNAseq | 0.0482 | 0.3527 |
Upregulated datasets: 0; Downregulated datasets: 3.
Survival by UBE2E1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of UBE2E1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | UBE2E1 | 7324 | 0 | 18 | 12 | |
| GSE20123 | UBE2E1 | 7324 | 0 | 18 | 12 | |
| GSE43470 | UBE2E1 | 7324 | 0 | 20 | 23 | |
| GSE46452 | UBE2E1 | 7324 | 2 | 17 | 40 | |
| GSE47630 | UBE2E1 | 7324 | 1 | 24 | 15 | |
| GSE54993 | UBE2E1 | 7324 | 6 | 2 | 62 | |
| GSE54994 | UBE2E1 | 7324 | 1 | 32 | 20 | |
| GSE60625 | UBE2E1 | 7324 | 5 | 0 | 6 | |
| GSE74703 | UBE2E1 | 7324 | 0 | 17 | 19 | |
| GSE74704 | UBE2E1 | 7324 | 0 | 12 | 8 | |
| TCGA | UBE2E1 | 7324 | 0 | 69 | 27 |
Total number of gains: 15; Total number of losses: 229; Total Number of normals: 244.
Somatic mutations of UBE2E1:
Generating mutation plots.
Highly correlated genes for UBE2E1:
Showing top 20/1593 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| UBE2E1 | BRK1 | 0.803457 | 6 | 0 | 6 |
| UBE2E1 | GGA3 | 0.77511 | 3 | 0 | 3 |
| UBE2E1 | ZKSCAN1 | 0.768017 | 3 | 0 | 3 |
| UBE2E1 | ACAA1 | 0.759034 | 9 | 0 | 7 |
| UBE2E1 | POLI | 0.758629 | 3 | 0 | 3 |
| UBE2E1 | GOLGA4 | 0.757697 | 10 | 0 | 8 |
| UBE2E1 | PPWD1 | 0.754125 | 3 | 0 | 3 |
| UBE2E1 | PITHD1 | 0.752313 | 6 | 0 | 5 |
| UBE2E1 | LRRFIP2 | 0.743142 | 12 | 0 | 11 |
| UBE2E1 | CPEB4 | 0.740395 | 7 | 0 | 7 |
| UBE2E1 | CGRRF1 | 0.739412 | 3 | 0 | 3 |
| UBE2E1 | GRHPR | 0.736859 | 5 | 0 | 5 |
| UBE2E1 | HDHD2 | 0.734896 | 5 | 0 | 4 |
| UBE2E1 | SYTL4 | 0.734074 | 3 | 0 | 3 |
| UBE2E1 | NPRL2 | 0.727443 | 6 | 0 | 5 |
| UBE2E1 | HIGD1A | 0.72715 | 13 | 0 | 12 |
| UBE2E1 | RAB5A | 0.726129 | 13 | 0 | 11 |
| UBE2E1 | RALGPS2 | 0.725866 | 7 | 0 | 7 |
| UBE2E1 | SLC46A2 | 0.723043 | 7 | 0 | 6 |
| UBE2E1 | NPEPPS | 0.722533 | 11 | 0 | 10 |
For details and further investigation, click here
