| Full name: actin related protein 2 | Alias Symbol: ARP2 | ||
| Type: protein-coding gene | Cytoband: 2p14 | ||
| Entrez ID: 10097 | HGNC ID: HGNC:169 | Ensembl Gene: ENSG00000138071 | OMIM ID: 604221 |
| Drug and gene relationship at DGIdb | |||
Expression of ACTR2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ACTR2 | 10097 | 200728_at | -0.0644 | 0.8984 | |
| GSE20347 | ACTR2 | 10097 | 200728_at | -0.1269 | 0.2744 | |
| GSE23400 | ACTR2 | 10097 | 200728_at | -0.0363 | 0.6629 | |
| GSE26886 | ACTR2 | 10097 | 200728_at | -1.3662 | 0.0000 | |
| GSE29001 | ACTR2 | 10097 | 200728_at | 0.0073 | 0.9834 | |
| GSE38129 | ACTR2 | 10097 | 200728_at | 0.1461 | 0.3918 | |
| GSE45670 | ACTR2 | 10097 | 200728_at | 0.0927 | 0.3468 | |
| GSE53622 | ACTR2 | 10097 | 136588 | 0.0952 | 0.1524 | |
| GSE53624 | ACTR2 | 10097 | 136588 | -0.2183 | 0.0012 | |
| GSE63941 | ACTR2 | 10097 | 200729_s_at | 0.1295 | 0.7336 | |
| GSE77861 | ACTR2 | 10097 | 200728_at | 0.1648 | 0.3236 | |
| GSE97050 | ACTR2 | 10097 | A_23_P377376 | 0.1203 | 0.7009 | |
| SRP007169 | ACTR2 | 10097 | RNAseq | -0.1244 | 0.6980 | |
| SRP008496 | ACTR2 | 10097 | RNAseq | -0.1478 | 0.3833 | |
| SRP064894 | ACTR2 | 10097 | RNAseq | -0.1424 | 0.5045 | |
| SRP133303 | ACTR2 | 10097 | RNAseq | 0.3668 | 0.0188 | |
| SRP159526 | ACTR2 | 10097 | RNAseq | 0.1106 | 0.5590 | |
| SRP193095 | ACTR2 | 10097 | RNAseq | -0.3555 | 0.0003 | |
| SRP219564 | ACTR2 | 10097 | RNAseq | -0.1006 | 0.7763 | |
| TCGA | ACTR2 | 10097 | RNAseq | 0.0853 | 0.0293 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by ACTR2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ACTR2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ACTR2 | 10097 | 12 | 0 | 18 | |
| GSE20123 | ACTR2 | 10097 | 12 | 0 | 18 | |
| GSE43470 | ACTR2 | 10097 | 6 | 1 | 36 | |
| GSE46452 | ACTR2 | 10097 | 2 | 3 | 54 | |
| GSE47630 | ACTR2 | 10097 | 8 | 0 | 32 | |
| GSE54993 | ACTR2 | 10097 | 0 | 6 | 64 | |
| GSE54994 | ACTR2 | 10097 | 12 | 0 | 41 | |
| GSE60625 | ACTR2 | 10097 | 0 | 3 | 8 | |
| GSE74703 | ACTR2 | 10097 | 6 | 1 | 29 | |
| GSE74704 | ACTR2 | 10097 | 10 | 0 | 10 | |
| TCGA | ACTR2 | 10097 | 36 | 2 | 58 |
Total number of gains: 104; Total number of losses: 16; Total Number of normals: 368.
Somatic mutations of ACTR2:
Generating mutation plots.
Highly correlated genes for ACTR2:
Showing top 20/580 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ACTR2 | CCNYL1 | 0.866346 | 3 | 0 | 3 |
| ACTR2 | MPP5 | 0.843093 | 3 | 0 | 3 |
| ACTR2 | APEH | 0.83752 | 3 | 0 | 3 |
| ACTR2 | TRERF1 | 0.826128 | 3 | 0 | 3 |
| ACTR2 | GLUD2 | 0.817774 | 3 | 0 | 3 |
| ACTR2 | SORD | 0.806169 | 3 | 0 | 3 |
| ACTR2 | ZNF770 | 0.803157 | 3 | 0 | 3 |
| ACTR2 | TET2 | 0.794167 | 3 | 0 | 3 |
| ACTR2 | JAK2 | 0.791551 | 3 | 0 | 3 |
| ACTR2 | SYK | 0.78803 | 3 | 0 | 3 |
| ACTR2 | MSH2 | 0.771286 | 3 | 0 | 3 |
| ACTR2 | ELK3 | 0.770705 | 3 | 0 | 3 |
| ACTR2 | WDFY1 | 0.766703 | 4 | 0 | 4 |
| ACTR2 | SLC11A2 | 0.762257 | 3 | 0 | 3 |
| ACTR2 | RABGAP1L | 0.760822 | 3 | 0 | 3 |
| ACTR2 | ANKRD50 | 0.760587 | 3 | 0 | 3 |
| ACTR2 | C3orf38 | 0.759657 | 4 | 0 | 4 |
| ACTR2 | ARPC1A | 0.758353 | 3 | 0 | 3 |
| ACTR2 | MAPK6 | 0.753787 | 3 | 0 | 3 |
| ACTR2 | TMEM218 | 0.750906 | 3 | 0 | 3 |
For details and further investigation, click here
