| Full name: G-patch domain containing 8 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 17q21.31 | ||
| Entrez ID: 23131 | HGNC ID: HGNC:29066 | Ensembl Gene: ENSG00000186566 | OMIM ID: 614396 |
| Drug and gene relationship at DGIdb | |||
Expression of GPATCH8:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GPATCH8 | 23131 | 212485_at | -0.2621 | 0.3570 | |
| GSE20347 | GPATCH8 | 23131 | 212487_at | -0.0225 | 0.8744 | |
| GSE23400 | GPATCH8 | 23131 | 212485_at | -0.0177 | 0.7930 | |
| GSE26886 | GPATCH8 | 23131 | 212487_at | 0.0649 | 0.7196 | |
| GSE29001 | GPATCH8 | 23131 | 212487_at | -0.0371 | 0.9207 | |
| GSE38129 | GPATCH8 | 23131 | 212487_at | -0.0323 | 0.8316 | |
| GSE45670 | GPATCH8 | 23131 | 212485_at | -0.0634 | 0.5279 | |
| GSE53622 | GPATCH8 | 23131 | 31384 | 0.0588 | 0.2052 | |
| GSE53624 | GPATCH8 | 23131 | 31384 | 0.2406 | 0.0000 | |
| GSE63941 | GPATCH8 | 23131 | 212485_at | 0.0857 | 0.7524 | |
| GSE77861 | GPATCH8 | 23131 | 212485_at | 0.1038 | 0.4585 | |
| GSE97050 | GPATCH8 | 23131 | A_24_P359117 | 0.0309 | 0.8912 | |
| SRP007169 | GPATCH8 | 23131 | RNAseq | 0.8121 | 0.0654 | |
| SRP008496 | GPATCH8 | 23131 | RNAseq | 0.9232 | 0.0030 | |
| SRP064894 | GPATCH8 | 23131 | RNAseq | -0.2366 | 0.3346 | |
| SRP133303 | GPATCH8 | 23131 | RNAseq | 0.0079 | 0.9250 | |
| SRP159526 | GPATCH8 | 23131 | RNAseq | -0.2616 | 0.2142 | |
| SRP193095 | GPATCH8 | 23131 | RNAseq | 0.0673 | 0.4904 | |
| SRP219564 | GPATCH8 | 23131 | RNAseq | -0.2794 | 0.3765 | |
| TCGA | GPATCH8 | 23131 | RNAseq | 0.0631 | 0.1586 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by GPATCH8 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GPATCH8:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GPATCH8 | 23131 | 5 | 2 | 23 | |
| GSE20123 | GPATCH8 | 23131 | 5 | 2 | 23 | |
| GSE43470 | GPATCH8 | 23131 | 1 | 2 | 40 | |
| GSE46452 | GPATCH8 | 23131 | 32 | 0 | 27 | |
| GSE47630 | GPATCH8 | 23131 | 9 | 0 | 31 | |
| GSE54993 | GPATCH8 | 23131 | 3 | 4 | 63 | |
| GSE54994 | GPATCH8 | 23131 | 8 | 5 | 40 | |
| GSE60625 | GPATCH8 | 23131 | 4 | 0 | 7 | |
| GSE74703 | GPATCH8 | 23131 | 1 | 1 | 34 | |
| GSE74704 | GPATCH8 | 23131 | 3 | 1 | 16 | |
| TCGA | GPATCH8 | 23131 | 24 | 7 | 65 |
Total number of gains: 95; Total number of losses: 24; Total Number of normals: 369.
Somatic mutations of GPATCH8:
Generating mutation plots.
Highly correlated genes for GPATCH8:
Showing top 20/69 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GPATCH8 | NAPG | 0.757276 | 3 | 0 | 3 |
| GPATCH8 | ZKSCAN1 | 0.734669 | 3 | 0 | 3 |
| GPATCH8 | PARD3 | 0.721876 | 3 | 0 | 3 |
| GPATCH8 | ASAP2 | 0.719045 | 3 | 0 | 3 |
| GPATCH8 | TUBB4B | 0.694079 | 3 | 0 | 3 |
| GPATCH8 | MAMDC4 | 0.689816 | 3 | 0 | 3 |
| GPATCH8 | SMO | 0.688221 | 3 | 0 | 3 |
| GPATCH8 | BARD1 | 0.673312 | 3 | 0 | 3 |
| GPATCH8 | HP1BP3 | 0.670689 | 3 | 0 | 3 |
| GPATCH8 | MAGT1 | 0.669531 | 3 | 0 | 3 |
| GPATCH8 | MIF4GD | 0.667582 | 3 | 0 | 3 |
| GPATCH8 | ANKRD36B | 0.667118 | 4 | 0 | 3 |
| GPATCH8 | AVEN | 0.666916 | 3 | 0 | 3 |
| GPATCH8 | CYP2C19 | 0.661826 | 4 | 0 | 4 |
| GPATCH8 | MAGI1 | 0.658734 | 4 | 0 | 4 |
| GPATCH8 | LDLR | 0.658239 | 3 | 0 | 3 |
| GPATCH8 | PLEKHA5 | 0.647106 | 4 | 0 | 4 |
| GPATCH8 | ZBTB43 | 0.636754 | 4 | 0 | 4 |
| GPATCH8 | RPL27A | 0.635039 | 4 | 0 | 3 |
| GPATCH8 | LGALSL | 0.633209 | 4 | 0 | 3 |
For details and further investigation, click here
