| Full name: inositol monophosphatase domain containing 1 | Alias Symbol: FLJ20421|IMPA3|gPAPP | ||
| Type: protein-coding gene | Cytoband: 8q12.1 | ||
| Entrez ID: 54928 | HGNC ID: HGNC:26019 | Ensembl Gene: ENSG00000104331 | OMIM ID: 614010 |
| Drug and gene relationship at DGIdb | |||
Expression of IMPAD1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | IMPAD1 | 54928 | 224743_at | 0.0959 | 0.8657 | |
| GSE20347 | IMPAD1 | 54928 | 218516_s_at | 1.0080 | 0.0000 | |
| GSE23400 | IMPAD1 | 54928 | 218516_s_at | 0.6735 | 0.0000 | |
| GSE26886 | IMPAD1 | 54928 | 224743_at | -0.0204 | 0.9440 | |
| GSE29001 | IMPAD1 | 54928 | 218516_s_at | 0.7076 | 0.0094 | |
| GSE38129 | IMPAD1 | 54928 | 218516_s_at | 0.9883 | 0.0000 | |
| GSE45670 | IMPAD1 | 54928 | 224743_at | -0.2618 | 0.0409 | |
| GSE53622 | IMPAD1 | 54928 | 30400 | 0.1597 | 0.0514 | |
| GSE53624 | IMPAD1 | 54928 | 30400 | 0.7199 | 0.0000 | |
| GSE63941 | IMPAD1 | 54928 | 222654_at | -1.6276 | 0.0095 | |
| GSE77861 | IMPAD1 | 54928 | 224743_at | 0.2892 | 0.1947 | |
| GSE97050 | IMPAD1 | 54928 | A_24_P166789 | -0.2332 | 0.4863 | |
| SRP007169 | IMPAD1 | 54928 | RNAseq | 0.4524 | 0.2840 | |
| SRP008496 | IMPAD1 | 54928 | RNAseq | 0.6439 | 0.0230 | |
| SRP064894 | IMPAD1 | 54928 | RNAseq | 0.4595 | 0.0224 | |
| SRP133303 | IMPAD1 | 54928 | RNAseq | 0.4717 | 0.0008 | |
| SRP159526 | IMPAD1 | 54928 | RNAseq | 0.4071 | 0.0112 | |
| SRP193095 | IMPAD1 | 54928 | RNAseq | 0.2797 | 0.0135 | |
| SRP219564 | IMPAD1 | 54928 | RNAseq | 0.3188 | 0.2722 | |
| TCGA | IMPAD1 | 54928 | RNAseq | -0.0316 | 0.4380 |
Upregulated datasets: 1; Downregulated datasets: 1.
Survival by IMPAD1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of IMPAD1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | IMPAD1 | 54928 | 14 | 1 | 15 | |
| GSE20123 | IMPAD1 | 54928 | 14 | 1 | 15 | |
| GSE43470 | IMPAD1 | 54928 | 13 | 3 | 27 | |
| GSE46452 | IMPAD1 | 54928 | 20 | 3 | 36 | |
| GSE47630 | IMPAD1 | 54928 | 23 | 1 | 16 | |
| GSE54993 | IMPAD1 | 54928 | 1 | 17 | 52 | |
| GSE54994 | IMPAD1 | 54928 | 30 | 0 | 23 | |
| GSE60625 | IMPAD1 | 54928 | 0 | 4 | 7 | |
| GSE74703 | IMPAD1 | 54928 | 12 | 2 | 22 | |
| GSE74704 | IMPAD1 | 54928 | 10 | 0 | 10 | |
| TCGA | IMPAD1 | 54928 | 43 | 7 | 46 |
Total number of gains: 180; Total number of losses: 39; Total Number of normals: 269.
Somatic mutations of IMPAD1:
Generating mutation plots.
Highly correlated genes for IMPAD1:
Showing top 20/759 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| IMPAD1 | RGL1 | 0.774345 | 3 | 0 | 3 |
| IMPAD1 | ZNF664 | 0.753191 | 3 | 0 | 3 |
| IMPAD1 | ERLEC1 | 0.733624 | 3 | 0 | 3 |
| IMPAD1 | ZMAT3 | 0.730169 | 3 | 0 | 3 |
| IMPAD1 | SRSF6 | 0.728306 | 3 | 0 | 3 |
| IMPAD1 | FAM118B | 0.727616 | 3 | 0 | 3 |
| IMPAD1 | PSMC1 | 0.722805 | 5 | 0 | 5 |
| IMPAD1 | SLC25A30 | 0.719709 | 3 | 0 | 3 |
| IMPAD1 | ZC3H14 | 0.710808 | 3 | 0 | 3 |
| IMPAD1 | NBR1 | 0.705534 | 3 | 0 | 3 |
| IMPAD1 | CSF1 | 0.704284 | 3 | 0 | 3 |
| IMPAD1 | C11orf58 | 0.702669 | 4 | 0 | 3 |
| IMPAD1 | CBLL1 | 0.699514 | 5 | 0 | 5 |
| IMPAD1 | TNFRSF19 | 0.697088 | 3 | 0 | 3 |
| IMPAD1 | MAGOHB | 0.694394 | 6 | 0 | 6 |
| IMPAD1 | SNX25 | 0.692101 | 3 | 0 | 3 |
| IMPAD1 | WTIP | 0.686593 | 4 | 0 | 3 |
| IMPAD1 | ATL1 | 0.685244 | 3 | 0 | 3 |
| IMPAD1 | FAM98B | 0.68179 | 4 | 0 | 4 |
| IMPAD1 | RUVBL1 | 0.680755 | 6 | 0 | 4 |
For details and further investigation, click here
