| Full name: zinc finger protein 354A | Alias Symbol: KID-1|EZNF|HKL1|KID1 | ||
| Type: protein-coding gene | Cytoband: 5q35.3 | ||
| Entrez ID: 6940 | HGNC ID: HGNC:11628 | Ensembl Gene: ENSG00000169131 | OMIM ID: 602444 |
| Drug and gene relationship at DGIdb | |||
Expression of ZNF354A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZNF354A | 6940 | 205427_at | 0.4884 | 0.3484 | |
| GSE20347 | ZNF354A | 6940 | 205427_at | 0.6680 | 0.0009 | |
| GSE23400 | ZNF354A | 6940 | 205427_at | 0.1018 | 0.0601 | |
| GSE26886 | ZNF354A | 6940 | 205427_at | 1.0228 | 0.0019 | |
| GSE29001 | ZNF354A | 6940 | 205427_at | 0.1893 | 0.4379 | |
| GSE38129 | ZNF354A | 6940 | 205427_at | 0.4799 | 0.0060 | |
| GSE45670 | ZNF354A | 6940 | 205427_at | 0.2890 | 0.1649 | |
| GSE53622 | ZNF354A | 6940 | 17537 | 0.4433 | 0.0000 | |
| GSE53624 | ZNF354A | 6940 | 17537 | 0.5124 | 0.0000 | |
| GSE63941 | ZNF354A | 6940 | 205427_at | 0.0440 | 0.9318 | |
| GSE77861 | ZNF354A | 6940 | 205427_at | 0.2755 | 0.2738 | |
| GSE97050 | ZNF354A | 6940 | A_23_P60565 | -0.0718 | 0.8397 | |
| SRP007169 | ZNF354A | 6940 | RNAseq | 1.2780 | 0.0259 | |
| SRP008496 | ZNF354A | 6940 | RNAseq | 1.5322 | 0.0027 | |
| SRP064894 | ZNF354A | 6940 | RNAseq | 0.3720 | 0.0206 | |
| SRP133303 | ZNF354A | 6940 | RNAseq | 0.7381 | 0.0000 | |
| SRP159526 | ZNF354A | 6940 | RNAseq | 0.8460 | 0.0007 | |
| SRP193095 | ZNF354A | 6940 | RNAseq | 0.2775 | 0.0276 | |
| SRP219564 | ZNF354A | 6940 | RNAseq | 0.7928 | 0.1069 | |
| TCGA | ZNF354A | 6940 | RNAseq | 0.0770 | 0.3412 |
Upregulated datasets: 3; Downregulated datasets: 0.
Survival by ZNF354A expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ZNF354A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZNF354A | 6940 | 2 | 13 | 15 | |
| GSE20123 | ZNF354A | 6940 | 2 | 13 | 15 | |
| GSE43470 | ZNF354A | 6940 | 1 | 11 | 31 | |
| GSE46452 | ZNF354A | 6940 | 0 | 27 | 32 | |
| GSE47630 | ZNF354A | 6940 | 1 | 20 | 19 | |
| GSE54993 | ZNF354A | 6940 | 10 | 2 | 58 | |
| GSE54994 | ZNF354A | 6940 | 2 | 17 | 34 | |
| GSE60625 | ZNF354A | 6940 | 1 | 0 | 10 | |
| GSE74703 | ZNF354A | 6940 | 1 | 7 | 28 | |
| GSE74704 | ZNF354A | 6940 | 1 | 6 | 13 | |
| TCGA | ZNF354A | 6940 | 9 | 34 | 53 |
Total number of gains: 30; Total number of losses: 150; Total Number of normals: 308.
Somatic mutations of ZNF354A:
Generating mutation plots.
Highly correlated genes for ZNF354A:
Showing top 20/772 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZNF354A | ANKRD9 | 0.825032 | 3 | 0 | 3 |
| ZNF354A | MOAP1 | 0.767647 | 3 | 0 | 3 |
| ZNF354A | NSMAF | 0.748965 | 3 | 0 | 3 |
| ZNF354A | RRAS2 | 0.742538 | 4 | 0 | 4 |
| ZNF354A | C1orf226 | 0.737325 | 3 | 0 | 3 |
| ZNF354A | RAD50 | 0.733438 | 3 | 0 | 3 |
| ZNF354A | FTO | 0.730648 | 3 | 0 | 3 |
| ZNF354A | KHNYN | 0.729006 | 3 | 0 | 3 |
| ZNF354A | DRAP1 | 0.722022 | 3 | 0 | 3 |
| ZNF354A | PPP1R16A | 0.721525 | 3 | 0 | 3 |
| ZNF354A | MRPL41 | 0.716984 | 3 | 0 | 3 |
| ZNF354A | ZNF142 | 0.71667 | 3 | 0 | 3 |
| ZNF354A | ZNF140 | 0.71481 | 3 | 0 | 3 |
| ZNF354A | MRPS9 | 0.713307 | 3 | 0 | 3 |
| ZNF354A | MRPL47 | 0.712327 | 4 | 0 | 4 |
| ZNF354A | NUDT15 | 0.711589 | 3 | 0 | 3 |
| ZNF354A | CDS2 | 0.711421 | 3 | 0 | 3 |
| ZNF354A | GGPS1 | 0.704507 | 5 | 0 | 4 |
| ZNF354A | IWS1 | 0.703204 | 4 | 0 | 3 |
| ZNF354A | HES4 | 0.700086 | 3 | 0 | 3 |
For details and further investigation, click here
