| Full name: E74 like ETS transcription factor 2 | Alias Symbol: EU32|NERF|NERF-2|NERF-1A|NERF-1B | ||
| Type: protein-coding gene | Cytoband: 4q31.1 | ||
| Entrez ID: 1998 | HGNC ID: HGNC:3317 | Ensembl Gene: ENSG00000109381 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of ELF2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ELF2 | 1998 | 203822_s_at | 0.1057 | 0.6758 | |
| GSE20347 | ELF2 | 1998 | 203822_s_at | -0.0688 | 0.5989 | |
| GSE23400 | ELF2 | 1998 | 203822_s_at | -0.0065 | 0.9134 | |
| GSE26886 | ELF2 | 1998 | 203822_s_at | -0.6552 | 0.0044 | |
| GSE29001 | ELF2 | 1998 | 203822_s_at | -0.0006 | 0.9976 | |
| GSE38129 | ELF2 | 1998 | 203822_s_at | -0.1895 | 0.0498 | |
| GSE45670 | ELF2 | 1998 | 203822_s_at | -0.4456 | 0.0002 | |
| GSE53622 | ELF2 | 1998 | 11226 | -0.3201 | 0.0000 | |
| GSE53624 | ELF2 | 1998 | 11226 | -0.0738 | 0.3146 | |
| GSE63941 | ELF2 | 1998 | 203822_s_at | -0.1935 | 0.4373 | |
| GSE77861 | ELF2 | 1998 | 242735_x_at | -0.0063 | 0.9611 | |
| GSE97050 | ELF2 | 1998 | A_33_P3212027 | 0.0672 | 0.8267 | |
| SRP007169 | ELF2 | 1998 | RNAseq | -0.4453 | 0.1925 | |
| SRP008496 | ELF2 | 1998 | RNAseq | -0.4121 | 0.0150 | |
| SRP064894 | ELF2 | 1998 | RNAseq | -0.2655 | 0.1082 | |
| SRP133303 | ELF2 | 1998 | RNAseq | -0.0130 | 0.9245 | |
| SRP159526 | ELF2 | 1998 | RNAseq | -0.4190 | 0.0057 | |
| SRP193095 | ELF2 | 1998 | RNAseq | -0.2135 | 0.0189 | |
| SRP219564 | ELF2 | 1998 | RNAseq | -0.3180 | 0.1805 | |
| TCGA | ELF2 | 1998 | RNAseq | -0.0947 | 0.0529 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ELF2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ELF2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ELF2 | 1998 | 0 | 12 | 18 | |
| GSE20123 | ELF2 | 1998 | 0 | 12 | 18 | |
| GSE43470 | ELF2 | 1998 | 0 | 13 | 30 | |
| GSE46452 | ELF2 | 1998 | 1 | 36 | 22 | |
| GSE47630 | ELF2 | 1998 | 0 | 22 | 18 | |
| GSE54993 | ELF2 | 1998 | 10 | 0 | 60 | |
| GSE54994 | ELF2 | 1998 | 2 | 11 | 40 | |
| GSE60625 | ELF2 | 1998 | 0 | 1 | 10 | |
| GSE74703 | ELF2 | 1998 | 0 | 11 | 25 | |
| GSE74704 | ELF2 | 1998 | 0 | 6 | 14 | |
| TCGA | ELF2 | 1998 | 10 | 33 | 53 |
Total number of gains: 23; Total number of losses: 157; Total Number of normals: 308.
Somatic mutations of ELF2:
Generating mutation plots.
Highly correlated genes for ELF2:
Showing top 20/596 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ELF2 | ZNF140 | 0.830251 | 3 | 0 | 3 |
| ELF2 | POLR3C | 0.823383 | 3 | 0 | 3 |
| ELF2 | ZNF322 | 0.801311 | 3 | 0 | 3 |
| ELF2 | FPGT | 0.776369 | 3 | 0 | 3 |
| ELF2 | TMEM129 | 0.744829 | 3 | 0 | 3 |
| ELF2 | ZNF92 | 0.740304 | 3 | 0 | 3 |
| ELF2 | ATG4C | 0.739926 | 4 | 0 | 4 |
| ELF2 | PIK3CB | 0.73008 | 4 | 0 | 4 |
| ELF2 | ZNF583 | 0.72926 | 3 | 0 | 3 |
| ELF2 | RBM18 | 0.725253 | 3 | 0 | 3 |
| ELF2 | DYRK2 | 0.722189 | 3 | 0 | 3 |
| ELF2 | SPATA2 | 0.721858 | 4 | 0 | 4 |
| ELF2 | CHAMP1 | 0.716183 | 3 | 0 | 3 |
| ELF2 | SYT17 | 0.71487 | 3 | 0 | 3 |
| ELF2 | EIF3C | 0.713698 | 3 | 0 | 3 |
| ELF2 | COIL | 0.713536 | 3 | 0 | 3 |
| ELF2 | CEP63 | 0.712763 | 4 | 0 | 3 |
| ELF2 | NIPAL3 | 0.712626 | 4 | 0 | 3 |
| ELF2 | PTAR1 | 0.712132 | 5 | 0 | 4 |
| ELF2 | NUB1 | 0.70946 | 4 | 0 | 4 |
For details and further investigation, click here
