| Full name: STT3 oligosaccharyltransferase complex catalytic subunit B | Alias Symbol: SIMP|FLJ90106|STT3-B | ||
| Type: protein-coding gene | Cytoband: 3p23 | ||
| Entrez ID: 201595 | HGNC ID: HGNC:30611 | Ensembl Gene: ENSG00000163527 | OMIM ID: 608605 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of STT3B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | STT3B | 201595 | 224700_at | 0.0024 | 0.9965 | |
| GSE26886 | STT3B | 201595 | 224700_at | -0.6076 | 0.0062 | |
| GSE45670 | STT3B | 201595 | 224700_at | -0.1998 | 0.0544 | |
| GSE53622 | STT3B | 201595 | 128996 | -0.2639 | 0.0000 | |
| GSE53624 | STT3B | 201595 | 128996 | -0.3141 | 0.0000 | |
| GSE63941 | STT3B | 201595 | 224700_at | -1.0160 | 0.0024 | |
| GSE77861 | STT3B | 201595 | 224700_at | -0.5936 | 0.0180 | |
| GSE97050 | STT3B | 201595 | A_23_P434473 | 0.0606 | 0.8266 | |
| SRP007169 | STT3B | 201595 | RNAseq | -0.4820 | 0.1354 | |
| SRP008496 | STT3B | 201595 | RNAseq | -0.0665 | 0.7652 | |
| SRP064894 | STT3B | 201595 | RNAseq | -0.3255 | 0.0181 | |
| SRP133303 | STT3B | 201595 | RNAseq | -0.2044 | 0.0873 | |
| SRP159526 | STT3B | 201595 | RNAseq | -0.4007 | 0.2060 | |
| SRP193095 | STT3B | 201595 | RNAseq | -0.6391 | 0.0000 | |
| SRP219564 | STT3B | 201595 | RNAseq | -0.4336 | 0.1472 | |
| TCGA | STT3B | 201595 | RNAseq | -0.1734 | 0.0002 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by STT3B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of STT3B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | STT3B | 201595 | 0 | 18 | 12 | |
| GSE20123 | STT3B | 201595 | 0 | 18 | 12 | |
| GSE43470 | STT3B | 201595 | 1 | 20 | 22 | |
| GSE46452 | STT3B | 201595 | 2 | 17 | 40 | |
| GSE47630 | STT3B | 201595 | 1 | 25 | 14 | |
| GSE54993 | STT3B | 201595 | 6 | 3 | 61 | |
| GSE54994 | STT3B | 201595 | 1 | 32 | 20 | |
| GSE60625 | STT3B | 201595 | 5 | 0 | 6 | |
| GSE74703 | STT3B | 201595 | 1 | 17 | 18 | |
| GSE74704 | STT3B | 201595 | 0 | 12 | 8 | |
| TCGA | STT3B | 201595 | 2 | 69 | 25 |
Total number of gains: 19; Total number of losses: 231; Total Number of normals: 238.
Somatic mutations of STT3B:
Generating mutation plots.
Highly correlated genes for STT3B:
Showing top 20/805 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| STT3B | PSENEN | 0.798524 | 3 | 0 | 3 |
| STT3B | VASN | 0.772546 | 3 | 0 | 3 |
| STT3B | ZNF709 | 0.768116 | 3 | 0 | 3 |
| STT3B | LPAR6 | 0.764766 | 4 | 0 | 4 |
| STT3B | TCAIM | 0.753748 | 4 | 0 | 4 |
| STT3B | CAPZA2 | 0.749531 | 3 | 0 | 3 |
| STT3B | PPP3CC | 0.740319 | 3 | 0 | 3 |
| STT3B | FBXO9 | 0.729417 | 3 | 0 | 3 |
| STT3B | TMEM165 | 0.728637 | 3 | 0 | 3 |
| STT3B | SLC43A3 | 0.727174 | 4 | 0 | 4 |
| STT3B | MRPS18B | 0.725727 | 3 | 0 | 3 |
| STT3B | YAP1 | 0.723972 | 4 | 0 | 3 |
| STT3B | MEIS1 | 0.723593 | 5 | 0 | 5 |
| STT3B | TRMT13 | 0.716213 | 3 | 0 | 3 |
| STT3B | ROR1 | 0.713597 | 3 | 0 | 3 |
| STT3B | IMPACT | 0.713478 | 3 | 0 | 3 |
| STT3B | ACO1 | 0.706417 | 3 | 0 | 3 |
| STT3B | NFIA | 0.705891 | 4 | 0 | 4 |
| STT3B | TMCO4 | 0.705753 | 4 | 0 | 4 |
| STT3B | KCTD21 | 0.703298 | 3 | 0 | 3 |
For details and further investigation, click here
