ZNF532

 

Full name: zinc finger protein 532 Alias Symbol: FLJ10697
Type: protein-coding gene Cytoband: 18q21.32
Entrez ID: 55205 HGNC ID: HGNC:30940 Ensembl Gene: ENSG00000074657 OMIM ID: 
Drug and gene relationship at DGIdb
Screen Evidence:

 

Expression of ZNF532:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 ZNF532 55205 220617_s_at 0.4597 0.3377
GSE20347 ZNF532 55205 220617_s_at 0.9756 0.0000
GSE23400 ZNF532 55205 220617_s_at 0.6747 0.0000
GSE26886 ZNF532 55205 225021_at 0.5867 0.1968
GSE29001 ZNF532 55205 220617_s_at 0.7031 0.0041
GSE38129 ZNF532 55205 220617_s_at 0.7455 0.0012
GSE45670 ZNF532 55205 220617_s_at 0.2280 0.2650
GSE53622 ZNF532 55205 21358 0.8155 0.0000
GSE53624 ZNF532 55205 21358 1.0564 0.0000
GSE63941 ZNF532 55205 220617_s_at -1.8428 0.0461
GSE77861 ZNF532 55205 220617_s_at 0.9622 0.0026
GSE97050 ZNF532 A_21_P0010834 -0.1239 0.6297
SRP007169 ZNF532 55205 RNAseq 1.5263 0.0001
SRP008496 ZNF532 55205 RNAseq 1.9334 0.0000
SRP064894 ZNF532 55205 RNAseq 0.5434 0.0071
SRP133303 ZNF532 55205 RNAseq 0.5126 0.0182
SRP159526 ZNF532 55205 RNAseq 0.5855 0.1111
SRP193095 ZNF532 55205 RNAseq 1.0715 0.0000
SRP219564 ZNF532 55205 RNAseq 0.0811 0.7742
TCGA ZNF532 55205 RNAseq 0.1923 0.0034

Upregulated datasets: 4; Downregulated datasets: 1.  

 

Survival by ZNF532 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of ZNF532:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 ZNF532 55205 2 8 20
GSE20123 ZNF532 55205 2 8 20
GSE43470 ZNF532 55205 0 5 38
GSE46452 ZNF532 55205 1 26 32
GSE47630 ZNF532 55205 5 20 15
GSE54993 ZNF532 55205 10 0 60
GSE54994 ZNF532 55205 0 18 35
GSE60625 ZNF532 55205 0 4 7
GSE74703 ZNF532 55205 0 5 31
GSE74704 ZNF532 55205 2 5 13
TCGA ZNF532 55205 9 44 43

Total number of gains: 31; Total number of losses: 143; Total Number of normals: 314.  

 

Somatic mutations of ZNF532:

 

Generating mutation plots.

 

Highly correlated genes for ZNF532:

 

Showing top 20/1425 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
ZNF532ZCCHC30.806837404
ZNF532ZNF3430.779478303
ZNF532FADS10.761001303
ZNF532RAB340.750626303
ZNF532CERS20.737487707
ZNF532RILPL20.724544303
ZNF532RABAC10.724445303
ZNF532UBR10.723721303
ZNF532ZFAND30.720344303
ZNF532TP53I130.718348505
ZNF532SMYD30.716225909
ZNF532FAM49A0.713204303
ZNF532MRPS60.710332303
ZNF532CALU0.70942511010
ZNF532ABI20.707227303
ZNF532RAI140.70443511010
ZNF532HIBADH0.704365505
ZNF532ENAH0.69873612011
ZNF532MMD0.69801711010
ZNF532NIPA10.69577303

For details and further investigation, click here