| Full name: ceramide synthase 2 | Alias Symbol: SP260|FLJ10243 | ||
| Type: protein-coding gene | Cytoband: 1q21.3 | ||
| Entrez ID: 29956 | HGNC ID: HGNC:14076 | Ensembl Gene: ENSG00000143418 | OMIM ID: 606920 |
Screen Evidence:
| |||
Expression of CERS2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CERS2 | 29956 | 222212_s_at | 0.6999 | 0.1004 | |
| GSE20347 | CERS2 | 29956 | 222212_s_at | 1.0424 | 0.0000 | |
| GSE23400 | CERS2 | 29956 | 222212_s_at | 0.7788 | 0.0000 | |
| GSE26886 | CERS2 | 29956 | 222212_s_at | 0.9112 | 0.0013 | |
| GSE29001 | CERS2 | 29956 | 222212_s_at | 0.9211 | 0.0041 | |
| GSE38129 | CERS2 | 29956 | 222212_s_at | 0.8841 | 0.0000 | |
| GSE45670 | CERS2 | 29956 | 222212_s_at | 0.4430 | 0.0286 | |
| GSE63941 | CERS2 | 29956 | 222212_s_at | -0.5170 | 0.1182 | |
| GSE77861 | CERS2 | 29956 | 222212_s_at | 1.1635 | 0.0068 | |
| GSE97050 | CERS2 | 29956 | A_23_P63010 | 0.4520 | 0.2139 | |
| SRP007169 | CERS2 | 29956 | RNAseq | 2.2274 | 0.0000 | |
| SRP008496 | CERS2 | 29956 | RNAseq | 2.4468 | 0.0000 | |
| SRP064894 | CERS2 | 29956 | RNAseq | 0.8371 | 0.0000 | |
| SRP133303 | CERS2 | 29956 | RNAseq | 0.8918 | 0.0000 | |
| SRP159526 | CERS2 | 29956 | RNAseq | 1.3641 | 0.0000 | |
| SRP193095 | CERS2 | 29956 | RNAseq | 0.7762 | 0.0001 | |
| SRP219564 | CERS2 | 29956 | RNAseq | 0.8862 | 0.0275 |
Upregulated datasets: 5; Downregulated datasets: 0.
Copy number change of CERS2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CERS2 | 29956 | 15 | 0 | 15 | |
| GSE20123 | CERS2 | 29956 | 15 | 0 | 15 | |
| GSE43470 | CERS2 | 29956 | 6 | 1 | 36 | |
| GSE46452 | CERS2 | 29956 | 2 | 1 | 56 | |
| GSE47630 | CERS2 | 29956 | 14 | 0 | 26 | |
| GSE54993 | CERS2 | 29956 | 0 | 4 | 66 | |
| GSE54994 | CERS2 | 29956 | 15 | 0 | 38 | |
| GSE60625 | CERS2 | 29956 | 0 | 0 | 11 | |
| GSE74703 | CERS2 | 29956 | 6 | 1 | 29 | |
| GSE74704 | CERS2 | 29956 | 7 | 0 | 13 | |
| TCGA | CERS2 | 29956 | 37 | 2 | 57 |
Total number of gains: 117; Total number of losses: 9; Total Number of normals: 362.
Somatic mutations of CERS2:
Generating mutation plots.
Highly correlated genes for CERS2:
Showing top 20/1708 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CERS2 | PTGFRN | 0.857116 | 3 | 0 | 3 |
| CERS2 | IRF2BPL | 0.809661 | 3 | 0 | 3 |
| CERS2 | FAM89B | 0.801161 | 3 | 0 | 3 |
| CERS2 | TIGD1 | 0.79754 | 3 | 0 | 3 |
| CERS2 | TUBA1B | 0.794183 | 7 | 0 | 7 |
| CERS2 | CPT1A | 0.787783 | 4 | 0 | 4 |
| CERS2 | ATP11C | 0.785387 | 3 | 0 | 3 |
| CERS2 | TEAD2 | 0.779411 | 4 | 0 | 4 |
| CERS2 | ZNF496 | 0.778529 | 5 | 0 | 5 |
| CERS2 | ZNF251 | 0.769461 | 3 | 0 | 3 |
| CERS2 | C15orf61 | 0.767862 | 3 | 0 | 3 |
| CERS2 | VPS72 | 0.76339 | 9 | 0 | 9 |
| CERS2 | HIBADH | 0.762011 | 4 | 0 | 4 |
| CERS2 | RILPL2 | 0.761929 | 3 | 0 | 3 |
| CERS2 | BRAT1 | 0.758635 | 5 | 0 | 5 |
| CERS2 | PARP1 | 0.758168 | 9 | 0 | 9 |
| CERS2 | TSEN15 | 0.754757 | 4 | 0 | 4 |
| CERS2 | LRP12 | 0.754508 | 10 | 0 | 9 |
| CERS2 | MRPL21 | 0.753305 | 3 | 0 | 3 |
| CERS2 | DESI2 | 0.752995 | 9 | 0 | 9 |
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