| Full name: family with sequence similarity 49 member A | Alias Symbol: DKFZP566A1524|FLJ11080 | ||
| Type: protein-coding gene | Cytoband: 2p24.2 | ||
| Entrez ID: 81553 | HGNC ID: HGNC:25373 | Ensembl Gene: ENSG00000197872 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of FAM49A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FAM49A | 81553 | 208092_s_at | 0.5609 | 0.2761 | |
| GSE20347 | FAM49A | 81553 | 208092_s_at | 0.2887 | 0.0719 | |
| GSE23400 | FAM49A | 81553 | 208092_s_at | 0.0437 | 0.3532 | |
| GSE26886 | FAM49A | 81553 | 208092_s_at | 0.9259 | 0.0000 | |
| GSE29001 | FAM49A | 81553 | 208092_s_at | 0.2753 | 0.4608 | |
| GSE38129 | FAM49A | 81553 | 208092_s_at | 0.3033 | 0.0541 | |
| GSE45670 | FAM49A | 81553 | 208092_s_at | 0.6150 | 0.0100 | |
| GSE53622 | FAM49A | 81553 | 33501 | -0.2846 | 0.0177 | |
| GSE53624 | FAM49A | 81553 | 33501 | 0.2736 | 0.0116 | |
| GSE63941 | FAM49A | 81553 | 208092_s_at | -0.5327 | 0.5742 | |
| GSE77861 | FAM49A | 81553 | 208092_s_at | 0.2327 | 0.2661 | |
| GSE97050 | FAM49A | 81553 | A_23_P21560 | -0.3241 | 0.3163 | |
| SRP007169 | FAM49A | 81553 | RNAseq | 1.5109 | 0.0021 | |
| SRP008496 | FAM49A | 81553 | RNAseq | 2.1392 | 0.0000 | |
| SRP064894 | FAM49A | 81553 | RNAseq | 0.5270 | 0.0595 | |
| SRP133303 | FAM49A | 81553 | RNAseq | 0.1952 | 0.3110 | |
| SRP159526 | FAM49A | 81553 | RNAseq | 0.1624 | 0.7873 | |
| SRP193095 | FAM49A | 81553 | RNAseq | 0.6054 | 0.0064 | |
| SRP219564 | FAM49A | 81553 | RNAseq | 0.8469 | 0.1947 | |
| TCGA | FAM49A | 81553 | RNAseq | 0.0475 | 0.7694 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by FAM49A expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FAM49A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FAM49A | 81553 | 9 | 2 | 19 | |
| GSE20123 | FAM49A | 81553 | 9 | 2 | 19 | |
| GSE43470 | FAM49A | 81553 | 2 | 0 | 41 | |
| GSE46452 | FAM49A | 81553 | 3 | 4 | 52 | |
| GSE47630 | FAM49A | 81553 | 7 | 0 | 33 | |
| GSE54993 | FAM49A | 81553 | 0 | 7 | 63 | |
| GSE54994 | FAM49A | 81553 | 10 | 0 | 43 | |
| GSE60625 | FAM49A | 81553 | 0 | 3 | 8 | |
| GSE74703 | FAM49A | 81553 | 2 | 0 | 34 | |
| GSE74704 | FAM49A | 81553 | 8 | 2 | 10 | |
| TCGA | FAM49A | 81553 | 35 | 3 | 58 |
Total number of gains: 85; Total number of losses: 23; Total Number of normals: 380.
Somatic mutations of FAM49A:
Generating mutation plots.
Highly correlated genes for FAM49A:
Showing top 20/901 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FAM49A | MRPL47 | 0.752951 | 3 | 0 | 3 |
| FAM49A | PCID2 | 0.743695 | 4 | 0 | 4 |
| FAM49A | LRP4 | 0.736691 | 3 | 0 | 3 |
| FAM49A | ALG10 | 0.73597 | 3 | 0 | 3 |
| FAM49A | GIMAP5 | 0.733225 | 3 | 0 | 3 |
| FAM49A | TP53I13 | 0.730732 | 4 | 0 | 3 |
| FAM49A | BIRC3 | 0.726525 | 4 | 0 | 3 |
| FAM49A | CTSH | 0.717462 | 4 | 0 | 4 |
| FAM49A | MED30 | 0.717087 | 4 | 0 | 4 |
| FAM49A | LIN7A | 0.715799 | 3 | 0 | 3 |
| FAM49A | CNRIP1 | 0.713955 | 4 | 0 | 4 |
| FAM49A | ZNF532 | 0.713204 | 3 | 0 | 3 |
| FAM49A | ABCC9 | 0.710895 | 3 | 0 | 3 |
| FAM49A | KRTCAP2 | 0.706254 | 3 | 0 | 3 |
| FAM49A | CLEC1A | 0.706245 | 3 | 0 | 3 |
| FAM49A | GRAMD1A | 0.705663 | 5 | 0 | 5 |
| FAM49A | C17orf80 | 0.705214 | 3 | 0 | 3 |
| FAM49A | RHOJ | 0.703724 | 3 | 0 | 3 |
| FAM49A | RABEP1 | 0.699526 | 4 | 0 | 4 |
| FAM49A | PTPRB | 0.699488 | 3 | 0 | 3 |
For details and further investigation, click here
