| Full name: ubiquitin conjugating enzyme E2 R2 | Alias Symbol: UBC3B|CDC34B|FLJ20419|MGC10481 | ||
| Type: protein-coding gene | Cytoband: 9p13.3 | ||
| Entrez ID: 54926 | HGNC ID: HGNC:19907 | Ensembl Gene: ENSG00000107341 | OMIM ID: 612506 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of UBE2R2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | UBE2R2 | 54926 | 223014_at | -0.3489 | 0.4167 | |
| GSE26886 | UBE2R2 | 54926 | 223014_at | -0.6742 | 0.0037 | |
| GSE45670 | UBE2R2 | 54926 | 223014_at | -0.2400 | 0.0867 | |
| GSE53622 | UBE2R2 | 54926 | 52550 | -0.4925 | 0.0000 | |
| GSE53624 | UBE2R2 | 54926 | 52550 | -0.3309 | 0.0000 | |
| GSE63941 | UBE2R2 | 54926 | 223014_at | -0.8493 | 0.0301 | |
| GSE77861 | UBE2R2 | 54926 | 223014_at | -0.2735 | 0.3816 | |
| GSE97050 | UBE2R2 | 54926 | A_33_P3333820 | -0.5678 | 0.0778 | |
| SRP007169 | UBE2R2 | 54926 | RNAseq | -1.5604 | 0.0006 | |
| SRP008496 | UBE2R2 | 54926 | RNAseq | -1.1995 | 0.0000 | |
| SRP064894 | UBE2R2 | 54926 | RNAseq | -0.2477 | 0.1205 | |
| SRP133303 | UBE2R2 | 54926 | RNAseq | -0.3046 | 0.0256 | |
| SRP159526 | UBE2R2 | 54926 | RNAseq | -0.4998 | 0.0151 | |
| SRP193095 | UBE2R2 | 54926 | RNAseq | -0.8373 | 0.0000 | |
| SRP219564 | UBE2R2 | 54926 | RNAseq | -0.2651 | 0.4681 | |
| TCGA | UBE2R2 | 54926 | RNAseq | -0.0098 | 0.8563 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by UBE2R2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of UBE2R2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | UBE2R2 | 54926 | 3 | 15 | 12 | |
| GSE20123 | UBE2R2 | 54926 | 3 | 15 | 12 | |
| GSE43470 | UBE2R2 | 54926 | 3 | 10 | 30 | |
| GSE46452 | UBE2R2 | 54926 | 6 | 15 | 38 | |
| GSE47630 | UBE2R2 | 54926 | 1 | 20 | 19 | |
| GSE54993 | UBE2R2 | 54926 | 6 | 0 | 64 | |
| GSE54994 | UBE2R2 | 54926 | 6 | 12 | 35 | |
| GSE60625 | UBE2R2 | 54926 | 0 | 0 | 11 | |
| GSE74703 | UBE2R2 | 54926 | 2 | 7 | 27 | |
| GSE74704 | UBE2R2 | 54926 | 0 | 12 | 8 | |
| TCGA | UBE2R2 | 54926 | 16 | 45 | 35 |
Total number of gains: 46; Total number of losses: 151; Total Number of normals: 291.
Somatic mutations of UBE2R2:
Generating mutation plots.
Highly correlated genes for UBE2R2:
Showing top 20/610 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| UBE2R2 | CCDC159 | 0.778289 | 3 | 0 | 3 |
| UBE2R2 | ARHGAP31 | 0.777075 | 3 | 0 | 3 |
| UBE2R2 | TMX4 | 0.767723 | 3 | 0 | 3 |
| UBE2R2 | CYP4V2 | 0.758644 | 3 | 0 | 3 |
| UBE2R2 | ZNF649 | 0.754114 | 3 | 0 | 3 |
| UBE2R2 | FGF7 | 0.750498 | 3 | 0 | 3 |
| UBE2R2 | AFF3 | 0.749806 | 3 | 0 | 3 |
| UBE2R2 | C7 | 0.744038 | 3 | 0 | 3 |
| UBE2R2 | CTSO | 0.743835 | 3 | 0 | 3 |
| UBE2R2 | GOLGA3 | 0.741401 | 3 | 0 | 3 |
| UBE2R2 | MACROD2 | 0.740189 | 3 | 0 | 3 |
| UBE2R2 | SARM1 | 0.729751 | 3 | 0 | 3 |
| UBE2R2 | RNF125 | 0.727487 | 3 | 0 | 3 |
| UBE2R2 | TCF21 | 0.727282 | 4 | 0 | 4 |
| UBE2R2 | DCP1A | 0.712865 | 3 | 0 | 3 |
| UBE2R2 | STK19 | 0.712756 | 5 | 0 | 5 |
| UBE2R2 | FYCO1 | 0.712643 | 3 | 0 | 3 |
| UBE2R2 | SOCS2 | 0.711829 | 3 | 0 | 3 |
| UBE2R2 | UQCRFS1 | 0.706777 | 4 | 0 | 4 |
| UBE2R2 | MED7 | 0.704454 | 3 | 0 | 3 |
For details and further investigation, click here
