| Full name: GRIP and coiled-coil domain containing 2 | Alias Symbol: GCC185|KIAA0336 | ||
| Type: protein-coding gene | Cytoband: 2q12.3 | ||
| Entrez ID: 9648 | HGNC ID: HGNC:23218 | Ensembl Gene: ENSG00000135968 | OMIM ID: 612711 |
| Drug and gene relationship at DGIdb | |||
Expression of GCC2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GCC2 | 9648 | 202832_at | -0.4296 | 0.1219 | |
| GSE20347 | GCC2 | 9648 | 202832_at | -0.3411 | 0.0308 | |
| GSE23400 | GCC2 | 9648 | 202832_at | -0.0900 | 0.3099 | |
| GSE26886 | GCC2 | 9648 | 202832_at | -0.7037 | 0.0143 | |
| GSE29001 | GCC2 | 9648 | 202832_at | -0.1301 | 0.6981 | |
| GSE38129 | GCC2 | 9648 | 202832_at | -0.4181 | 0.0041 | |
| GSE45670 | GCC2 | 9648 | 202832_at | -0.4552 | 0.0018 | |
| GSE53622 | GCC2 | 9648 | 18570 | -0.2271 | 0.0005 | |
| GSE53624 | GCC2 | 9648 | 9386 | -0.3800 | 0.0000 | |
| GSE63941 | GCC2 | 9648 | 202832_at | -1.4018 | 0.0631 | |
| GSE77861 | GCC2 | 9648 | 202832_at | -0.0441 | 0.9226 | |
| GSE97050 | GCC2 | 9648 | A_33_P3247933 | -0.3749 | 0.1590 | |
| SRP007169 | GCC2 | 9648 | RNAseq | -0.5448 | 0.1184 | |
| SRP008496 | GCC2 | 9648 | RNAseq | -0.2517 | 0.2650 | |
| SRP064894 | GCC2 | 9648 | RNAseq | -0.3136 | 0.2230 | |
| SRP133303 | GCC2 | 9648 | RNAseq | 0.0853 | 0.5304 | |
| SRP159526 | GCC2 | 9648 | RNAseq | -0.1063 | 0.6368 | |
| SRP193095 | GCC2 | 9648 | RNAseq | -0.5045 | 0.0063 | |
| SRP219564 | GCC2 | 9648 | RNAseq | -0.4649 | 0.1734 | |
| TCGA | GCC2 | 9648 | RNAseq | -0.3515 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by GCC2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GCC2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GCC2 | 9648 | 3 | 2 | 25 | |
| GSE20123 | GCC2 | 9648 | 3 | 2 | 25 | |
| GSE43470 | GCC2 | 9648 | 3 | 1 | 39 | |
| GSE46452 | GCC2 | 9648 | 1 | 4 | 54 | |
| GSE47630 | GCC2 | 9648 | 7 | 0 | 33 | |
| GSE54993 | GCC2 | 9648 | 0 | 6 | 64 | |
| GSE54994 | GCC2 | 9648 | 10 | 0 | 43 | |
| GSE60625 | GCC2 | 9648 | 0 | 3 | 8 | |
| GSE74703 | GCC2 | 9648 | 3 | 1 | 32 | |
| GSE74704 | GCC2 | 9648 | 2 | 2 | 16 | |
| TCGA | GCC2 | 9648 | 31 | 6 | 59 |
Total number of gains: 63; Total number of losses: 27; Total Number of normals: 398.
Somatic mutations of GCC2:
Generating mutation plots.
Highly correlated genes for GCC2:
Showing top 20/829 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GCC2 | ZNF638 | 0.792078 | 3 | 0 | 3 |
| GCC2 | KIAA1191 | 0.77125 | 3 | 0 | 3 |
| GCC2 | PNPLA8 | 0.767414 | 3 | 0 | 3 |
| GCC2 | HDHD2 | 0.756167 | 3 | 0 | 3 |
| GCC2 | QRICH1 | 0.746889 | 3 | 0 | 3 |
| GCC2 | RNF185 | 0.743205 | 3 | 0 | 3 |
| GCC2 | STAU2 | 0.742212 | 3 | 0 | 3 |
| GCC2 | SLC35B3 | 0.738699 | 4 | 0 | 4 |
| GCC2 | PLEKHH2 | 0.737902 | 3 | 0 | 3 |
| GCC2 | LNPEP | 0.736194 | 3 | 0 | 3 |
| GCC2 | ALKBH7 | 0.728279 | 3 | 0 | 3 |
| GCC2 | CDC26 | 0.725669 | 3 | 0 | 3 |
| GCC2 | RWDD2B | 0.722886 | 3 | 0 | 3 |
| GCC2 | CNOT4 | 0.720921 | 3 | 0 | 3 |
| GCC2 | ZNF649 | 0.717267 | 3 | 0 | 3 |
| GCC2 | RSRC2 | 0.712115 | 4 | 0 | 3 |
| GCC2 | ZNF800 | 0.709826 | 3 | 0 | 3 |
| GCC2 | BDP1 | 0.709493 | 3 | 0 | 3 |
| GCC2 | NPY1R | 0.708681 | 4 | 0 | 3 |
| GCC2 | COG3 | 0.704652 | 4 | 0 | 4 |
For details and further investigation, click here
