| Full name: BTB domain and CNC homolog 1 | Alias Symbol: BACH-1|BTBD24 | ||
| Type: protein-coding gene | Cytoband: 21q21.3 | ||
| Entrez ID: 571 | HGNC ID: HGNC:935 | Ensembl Gene: ENSG00000156273 | OMIM ID: 602751 |
| Drug and gene relationship at DGIdb | |||
Expression of BACH1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | BACH1 | 571 | 204194_at | -0.6763 | 0.2060 | |
| GSE20347 | BACH1 | 571 | 204194_at | -0.6289 | 0.0002 | |
| GSE23400 | BACH1 | 571 | 204194_at | -0.1458 | 0.0922 | |
| GSE26886 | BACH1 | 571 | 204194_at | -1.8918 | 0.0000 | |
| GSE29001 | BACH1 | 571 | 204194_at | -0.4642 | 0.3164 | |
| GSE38129 | BACH1 | 571 | 204194_at | -0.3789 | 0.0419 | |
| GSE45670 | BACH1 | 571 | 204194_at | -0.1122 | 0.7260 | |
| GSE53622 | BACH1 | 571 | 138623 | -0.2092 | 0.0099 | |
| GSE53624 | BACH1 | 571 | 35321 | -0.5652 | 0.0000 | |
| GSE63941 | BACH1 | 571 | 204194_at | -1.2358 | 0.0155 | |
| GSE77861 | BACH1 | 571 | 204194_at | -0.7164 | 0.0587 | |
| GSE97050 | BACH1 | 571 | A_23_P211047 | -0.0249 | 0.9500 | |
| SRP007169 | BACH1 | 571 | RNAseq | -1.4261 | 0.0000 | |
| SRP008496 | BACH1 | 571 | RNAseq | -1.0045 | 0.0001 | |
| SRP064894 | BACH1 | 571 | RNAseq | -0.3983 | 0.1795 | |
| SRP133303 | BACH1 | 571 | RNAseq | -0.3268 | 0.0154 | |
| SRP159526 | BACH1 | 571 | RNAseq | -0.8014 | 0.0672 | |
| SRP193095 | BACH1 | 571 | RNAseq | -0.2860 | 0.0419 | |
| SRP219564 | BACH1 | 571 | RNAseq | -0.9465 | 0.0301 | |
| TCGA | BACH1 | 571 | RNAseq | 0.0935 | 0.0776 |
Upregulated datasets: 0; Downregulated datasets: 4.
Survival by BACH1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of BACH1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | BACH1 | 571 | 2 | 10 | 18 | |
| GSE20123 | BACH1 | 571 | 2 | 10 | 18 | |
| GSE43470 | BACH1 | 571 | 1 | 8 | 34 | |
| GSE46452 | BACH1 | 571 | 1 | 21 | 37 | |
| GSE47630 | BACH1 | 571 | 6 | 17 | 17 | |
| GSE54993 | BACH1 | 571 | 9 | 1 | 60 | |
| GSE54994 | BACH1 | 571 | 1 | 9 | 43 | |
| GSE60625 | BACH1 | 571 | 0 | 0 | 11 | |
| GSE74703 | BACH1 | 571 | 1 | 6 | 29 | |
| GSE74704 | BACH1 | 571 | 2 | 6 | 12 | |
| TCGA | BACH1 | 571 | 9 | 39 | 48 |
Total number of gains: 34; Total number of losses: 127; Total Number of normals: 327.
Somatic mutations of BACH1:
Generating mutation plots.
Highly correlated genes for BACH1:
Showing top 20/1221 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| BACH1 | ZDHHC21 | 0.844224 | 4 | 0 | 4 |
| BACH1 | FAR1 | 0.840454 | 3 | 0 | 3 |
| BACH1 | ZNF92 | 0.791868 | 3 | 0 | 3 |
| BACH1 | UBQLN1 | 0.766555 | 3 | 0 | 3 |
| BACH1 | ZNF879 | 0.76053 | 3 | 0 | 3 |
| BACH1 | MTMR3 | 0.755768 | 6 | 0 | 6 |
| BACH1 | ZNF823 | 0.751888 | 5 | 0 | 4 |
| BACH1 | CLDND1 | 0.746175 | 3 | 0 | 3 |
| BACH1 | BRWD3 | 0.744668 | 3 | 0 | 3 |
| BACH1 | GSKIP | 0.744219 | 4 | 0 | 4 |
| BACH1 | TBC1D22B | 0.743644 | 4 | 0 | 3 |
| BACH1 | ZNF649 | 0.735675 | 3 | 0 | 3 |
| BACH1 | STX19 | 0.732885 | 3 | 0 | 3 |
| BACH1 | TRAPPC6B | 0.732555 | 3 | 0 | 3 |
| BACH1 | ZNF416 | 0.730622 | 4 | 0 | 4 |
| BACH1 | SIAE | 0.727217 | 4 | 0 | 4 |
| BACH1 | TBC1D20 | 0.724573 | 4 | 0 | 3 |
| BACH1 | SLC46A2 | 0.720749 | 5 | 0 | 5 |
| BACH1 | SOCS6 | 0.719359 | 7 | 0 | 7 |
| BACH1 | ESYT2 | 0.71709 | 4 | 0 | 3 |
For details and further investigation, click here
