| Full name: splicing factor 3a subunit 3 | Alias Symbol: SF3a60|SAP61|PRP9|PRPF9 | ||
| Type: protein-coding gene | Cytoband: 1p34.3 | ||
| Entrez ID: 10946 | HGNC ID: HGNC:10767 | Ensembl Gene: ENSG00000183431 | OMIM ID: 605596 |
| Drug and gene relationship at DGIdb | |||
Expression of SF3A3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SF3A3 | 10946 | 203818_s_at | 0.1103 | 0.8433 | |
| GSE20347 | SF3A3 | 10946 | 203818_s_at | 0.0118 | 0.9384 | |
| GSE23400 | SF3A3 | 10946 | 203818_s_at | 0.2674 | 0.0000 | |
| GSE26886 | SF3A3 | 10946 | 203818_s_at | 0.3092 | 0.3021 | |
| GSE29001 | SF3A3 | 10946 | 203818_s_at | -0.0851 | 0.7676 | |
| GSE38129 | SF3A3 | 10946 | 203818_s_at | 0.0430 | 0.7463 | |
| GSE45670 | SF3A3 | 10946 | 203818_s_at | 0.0084 | 0.9615 | |
| GSE63941 | SF3A3 | 10946 | 203818_s_at | -0.1208 | 0.8620 | |
| GSE77861 | SF3A3 | 10946 | 203818_s_at | 0.2983 | 0.1732 | |
| GSE97050 | SF3A3 | 10946 | A_24_P603224 | 0.3610 | 0.2185 | |
| SRP007169 | SF3A3 | 10946 | RNAseq | 0.8584 | 0.0418 | |
| SRP008496 | SF3A3 | 10946 | RNAseq | 0.8463 | 0.0027 | |
| SRP064894 | SF3A3 | 10946 | RNAseq | 0.4646 | 0.0001 | |
| SRP133303 | SF3A3 | 10946 | RNAseq | 0.3739 | 0.0070 | |
| SRP159526 | SF3A3 | 10946 | RNAseq | 0.3179 | 0.1479 | |
| SRP193095 | SF3A3 | 10946 | RNAseq | 0.2465 | 0.0053 | |
| SRP219564 | SF3A3 | 10946 | RNAseq | 0.5713 | 0.1919 | |
| TCGA | SF3A3 | 10946 | RNAseq | 0.1335 | 0.0072 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by SF3A3 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of SF3A3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SF3A3 | 10946 | 2 | 4 | 24 | |
| GSE20123 | SF3A3 | 10946 | 2 | 3 | 25 | |
| GSE43470 | SF3A3 | 10946 | 7 | 3 | 33 | |
| GSE46452 | SF3A3 | 10946 | 4 | 1 | 54 | |
| GSE47630 | SF3A3 | 10946 | 8 | 3 | 29 | |
| GSE54993 | SF3A3 | 10946 | 0 | 1 | 69 | |
| GSE54994 | SF3A3 | 10946 | 12 | 2 | 39 | |
| GSE60625 | SF3A3 | 10946 | 0 | 0 | 11 | |
| GSE74703 | SF3A3 | 10946 | 6 | 2 | 28 | |
| GSE74704 | SF3A3 | 10946 | 1 | 0 | 19 | |
| TCGA | SF3A3 | 10946 | 12 | 17 | 67 |
Total number of gains: 54; Total number of losses: 36; Total Number of normals: 398.
Somatic mutations of SF3A3:
Generating mutation plots.
Highly correlated genes for SF3A3:
Showing top 20/55 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SF3A3 | GPAM | 0.723207 | 3 | 0 | 3 |
| SF3A3 | PRR15 | 0.704491 | 3 | 0 | 3 |
| SF3A3 | FBXO22 | 0.687378 | 3 | 0 | 3 |
| SF3A3 | RAD51C | 0.685871 | 4 | 0 | 3 |
| SF3A3 | TIMM10 | 0.676104 | 4 | 0 | 3 |
| SF3A3 | MECR | 0.673139 | 3 | 0 | 3 |
| SF3A3 | C16orf91 | 0.669437 | 3 | 0 | 3 |
| SF3A3 | COPS7B | 0.660896 | 5 | 0 | 4 |
| SF3A3 | ABCB9 | 0.65718 | 3 | 0 | 3 |
| SF3A3 | TIMM22 | 0.651067 | 3 | 0 | 3 |
| SF3A3 | ZNF684 | 0.646574 | 4 | 0 | 3 |
| SF3A3 | TK1 | 0.644303 | 3 | 0 | 3 |
| SF3A3 | CBX3 | 0.644112 | 4 | 0 | 4 |
| SF3A3 | EDEM3 | 0.642517 | 3 | 0 | 3 |
| SF3A3 | ORC6 | 0.639355 | 3 | 0 | 3 |
| SF3A3 | SDCCAG8 | 0.626768 | 3 | 0 | 3 |
| SF3A3 | RAD51 | 0.623133 | 4 | 0 | 3 |
| SF3A3 | FBXL15 | 0.62021 | 4 | 0 | 3 |
| SF3A3 | YEATS4 | 0.618333 | 4 | 0 | 3 |
| SF3A3 | ABT1 | 0.61565 | 4 | 0 | 3 |
For details and further investigation, click here
