TMEM39B

 

Full name: transmembrane protein 39B Alias Symbol: FLJ10315
Type: protein-coding gene Cytoband: 1p35.2
Entrez ID: 55116 HGNC ID: HGNC:25510 Ensembl Gene: ENSG00000121775 OMIM ID: 
Drug and gene relationship at DGIdb

 

Expression of TMEM39B:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 TMEM39B 55116 218770_s_at 0.5172 0.0791
GSE20347 TMEM39B 55116 218770_s_at 0.5306 0.0014
GSE23400 TMEM39B 55116 218770_s_at 0.3203 0.0000
GSE26886 TMEM39B 55116 218770_s_at 0.4119 0.0086
GSE29001 TMEM39B 55116 218770_s_at 0.5760 0.0041
GSE38129 TMEM39B 55116 218770_s_at 0.6037 0.0000
GSE45670 TMEM39B 55116 218770_s_at 0.4552 0.0041
GSE53622 TMEM39B 55116 66671 0.4372 0.0000
GSE53624 TMEM39B 55116 66671 0.6382 0.0000
GSE63941 TMEM39B 55116 218770_s_at 0.3825 0.4162
GSE77861 TMEM39B 55116 218770_s_at 0.3060 0.2608
GSE97050 TMEM39B 55116 A_23_P34496 0.3102 0.3833
SRP007169 TMEM39B 55116 RNAseq 0.4187 0.4485
SRP008496 TMEM39B 55116 RNAseq 0.5250 0.2261
SRP064894 TMEM39B 55116 RNAseq 1.2613 0.0000
SRP133303 TMEM39B 55116 RNAseq 0.2478 0.1049
SRP159526 TMEM39B 55116 RNAseq 0.5757 0.1214
SRP193095 TMEM39B 55116 RNAseq 0.4225 0.0000
SRP219564 TMEM39B 55116 RNAseq 0.4236 0.1537
TCGA TMEM39B 55116 RNAseq 0.2700 0.0000

Upregulated datasets: 1; Downregulated datasets: 0.  

 

Survival by TMEM39B expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of TMEM39B:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 TMEM39B 55116 1 5 24
GSE20123 TMEM39B 55116 1 4 25
GSE43470 TMEM39B 55116 6 4 33
GSE46452 TMEM39B 55116 5 1 53
GSE47630 TMEM39B 55116 8 3 29
GSE54993 TMEM39B 55116 1 1 68
GSE54994 TMEM39B 55116 11 2 40
GSE60625 TMEM39B 55116 0 0 11
GSE74703 TMEM39B 55116 4 3 29
GSE74704 TMEM39B 55116 0 0 20
TCGA TMEM39B 55116 11 21 64

Total number of gains: 48; Total number of losses: 44; Total Number of normals: 396.  

 

Somatic mutations of TMEM39B:

 

Generating mutation plots.

 

Highly correlated genes for TMEM39B:

 

Showing top 20/1239 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
TMEM39BKIF2C0.66946412011
TMEM39BPTK70.66907111010
TMEM39BPSMB20.66747112011
TMEM39BYBX10.665755808
TMEM39BTUBA1C0.659484706
TMEM39BUBE2C0.65771512011
TMEM39BPLXNA10.65769910010
TMEM39BCDC200.65496411010
TMEM39BLRR10.654195404
TMEM39BWDR540.653963605
TMEM39BPRR120.652692303
TMEM39BMCM20.6504541109
TMEM39BNAT140.650296606
TMEM39BLSAMP-AS10.649628303
TMEM39BKDM1A0.6484421109
TMEM39BRPN10.6478341009
TMEM39BEHMT20.647695605
TMEM39BMND10.647663605
TMEM39BKNSTRN0.645763504
TMEM39BNASP0.64149412010

For details and further investigation, click here