| Full name: SDS3 homolog, SIN3A corepressor complex component | Alias Symbol: SDS3|FLJ00052|SAP45 | ||
| Type: protein-coding gene | Cytoband: 12q24.23 | ||
| Entrez ID: 64426 | HGNC ID: HGNC:29545 | Ensembl Gene: ENSG00000111707 | OMIM ID: 608250 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of SUDS3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SUDS3 | 64426 | 224974_at | -0.0978 | 0.8991 | |
| GSE26886 | SUDS3 | 64426 | 224974_at | -0.7660 | 0.0036 | |
| GSE45670 | SUDS3 | 64426 | 224974_at | -0.2482 | 0.0720 | |
| GSE53622 | SUDS3 | 64426 | 43043 | -0.0420 | 0.5071 | |
| GSE53624 | SUDS3 | 64426 | 43043 | -0.1130 | 0.0713 | |
| GSE63941 | SUDS3 | 64426 | 224974_at | -0.0971 | 0.8704 | |
| GSE77861 | SUDS3 | 64426 | 224974_at | -0.2472 | 0.3932 | |
| GSE97050 | SUDS3 | 64426 | A_23_P334990 | 0.1968 | 0.3534 | |
| SRP007169 | SUDS3 | 64426 | RNAseq | 0.5208 | 0.1620 | |
| SRP008496 | SUDS3 | 64426 | RNAseq | 0.4690 | 0.0236 | |
| SRP064894 | SUDS3 | 64426 | RNAseq | -0.2350 | 0.0830 | |
| SRP133303 | SUDS3 | 64426 | RNAseq | -0.2624 | 0.0192 | |
| SRP159526 | SUDS3 | 64426 | RNAseq | 0.1493 | 0.4303 | |
| SRP193095 | SUDS3 | 64426 | RNAseq | -0.3097 | 0.0000 | |
| SRP219564 | SUDS3 | 64426 | RNAseq | -0.4796 | 0.0238 | |
| TCGA | SUDS3 | 64426 | RNAseq | -0.0382 | 0.4179 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by SUDS3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SUDS3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SUDS3 | 64426 | 6 | 2 | 22 | |
| GSE20123 | SUDS3 | 64426 | 6 | 2 | 22 | |
| GSE43470 | SUDS3 | 64426 | 2 | 1 | 40 | |
| GSE46452 | SUDS3 | 64426 | 9 | 1 | 49 | |
| GSE47630 | SUDS3 | 64426 | 9 | 3 | 28 | |
| GSE54993 | SUDS3 | 64426 | 0 | 5 | 65 | |
| GSE54994 | SUDS3 | 64426 | 6 | 6 | 41 | |
| GSE60625 | SUDS3 | 64426 | 0 | 0 | 11 | |
| GSE74703 | SUDS3 | 64426 | 2 | 0 | 34 | |
| GSE74704 | SUDS3 | 64426 | 3 | 2 | 15 | |
| TCGA | SUDS3 | 64426 | 21 | 11 | 64 |
Total number of gains: 64; Total number of losses: 33; Total Number of normals: 391.
Somatic mutations of SUDS3:
Generating mutation plots.
Highly correlated genes for SUDS3:
Showing top 20/69 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SUDS3 | ABAT | 0.747433 | 3 | 0 | 3 |
| SUDS3 | LARP4B | 0.728433 | 3 | 0 | 3 |
| SUDS3 | IRGQ | 0.724827 | 3 | 0 | 3 |
| SUDS3 | ZNF780A | 0.721005 | 3 | 0 | 3 |
| SUDS3 | SHOC2 | 0.699782 | 4 | 0 | 3 |
| SUDS3 | ZNF684 | 0.699539 | 3 | 0 | 3 |
| SUDS3 | GCH1 | 0.688447 | 3 | 0 | 3 |
| SUDS3 | SNX31 | 0.681931 | 3 | 0 | 3 |
| SUDS3 | ZNF682 | 0.681642 | 4 | 0 | 3 |
| SUDS3 | FBXO34 | 0.680476 | 4 | 0 | 3 |
| SUDS3 | GRIPAP1 | 0.673956 | 3 | 0 | 3 |
| SUDS3 | CCDC96 | 0.673782 | 3 | 0 | 3 |
| SUDS3 | RIPK4 | 0.671669 | 4 | 0 | 3 |
| SUDS3 | ATP7B | 0.666054 | 3 | 0 | 3 |
| SUDS3 | TRIM41 | 0.664417 | 4 | 0 | 3 |
| SUDS3 | LIAS | 0.660462 | 3 | 0 | 3 |
| SUDS3 | UBN2 | 0.655826 | 5 | 0 | 4 |
| SUDS3 | NHP2 | 0.648775 | 3 | 0 | 3 |
| SUDS3 | CYP2E1 | 0.64743 | 3 | 0 | 3 |
| SUDS3 | NUDT12 | 0.640998 | 3 | 0 | 3 |
For details and further investigation, click here
