| Full name: phospholipase C like 2 | Alias Symbol: KIAA1092 | ||
| Type: protein-coding gene | Cytoband: 3p24.3 | ||
| Entrez ID: 23228 | HGNC ID: HGNC:9064 | Ensembl Gene: ENSG00000154822 | OMIM ID: 614276 |
| Drug and gene relationship at DGIdb | |||
Expression of PLCL2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PLCL2 | 23228 | 213309_at | -0.0132 | 0.9928 | |
| GSE20347 | PLCL2 | 23228 | 213309_at | 0.1063 | 0.3263 | |
| GSE23400 | PLCL2 | 23228 | 213309_at | 0.0297 | 0.4894 | |
| GSE26886 | PLCL2 | 23228 | 213309_at | 0.3912 | 0.3845 | |
| GSE29001 | PLCL2 | 23228 | 213309_at | 0.2346 | 0.5252 | |
| GSE38129 | PLCL2 | 23228 | 213309_at | -0.1553 | 0.5204 | |
| GSE45670 | PLCL2 | 23228 | 213309_at | -0.5487 | 0.0577 | |
| GSE53622 | PLCL2 | 23228 | 109460 | -0.1448 | 0.3637 | |
| GSE53624 | PLCL2 | 23228 | 109460 | 0.0340 | 0.8680 | |
| GSE63941 | PLCL2 | 23228 | 213309_at | -2.1901 | 0.0022 | |
| GSE77861 | PLCL2 | 23228 | 216217_at | -0.0179 | 0.9077 | |
| GSE97050 | PLCL2 | 23228 | A_24_P281988 | 0.2422 | 0.3445 | |
| SRP007169 | PLCL2 | 23228 | RNAseq | 0.9603 | 0.1640 | |
| SRP064894 | PLCL2 | 23228 | RNAseq | 0.4267 | 0.1828 | |
| SRP133303 | PLCL2 | 23228 | RNAseq | -0.2702 | 0.1934 | |
| SRP159526 | PLCL2 | 23228 | RNAseq | -0.3762 | 0.5701 | |
| SRP193095 | PLCL2 | 23228 | RNAseq | -0.5754 | 0.1149 | |
| SRP219564 | PLCL2 | 23228 | RNAseq | 0.7104 | 0.1210 | |
| TCGA | PLCL2 | 23228 | RNAseq | -0.8144 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by PLCL2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PLCL2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PLCL2 | 23228 | 1 | 18 | 11 | |
| GSE20123 | PLCL2 | 23228 | 1 | 18 | 11 | |
| GSE43470 | PLCL2 | 23228 | 0 | 20 | 23 | |
| GSE46452 | PLCL2 | 23228 | 2 | 17 | 40 | |
| GSE47630 | PLCL2 | 23228 | 1 | 24 | 15 | |
| GSE54993 | PLCL2 | 23228 | 6 | 1 | 63 | |
| GSE54994 | PLCL2 | 23228 | 1 | 32 | 20 | |
| GSE60625 | PLCL2 | 23228 | 5 | 0 | 6 | |
| GSE74703 | PLCL2 | 23228 | 0 | 17 | 19 | |
| GSE74704 | PLCL2 | 23228 | 1 | 12 | 7 | |
| TCGA | PLCL2 | 23228 | 1 | 68 | 27 |
Total number of gains: 19; Total number of losses: 227; Total Number of normals: 242.
Somatic mutations of PLCL2:
Generating mutation plots.
Highly correlated genes for PLCL2:
Showing top 20/266 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PLCL2 | RASGRF2 | 0.748229 | 3 | 0 | 3 |
| PLCL2 | ZCCHC18 | 0.702575 | 5 | 0 | 5 |
| PLCL2 | MPEG1 | 0.698274 | 5 | 0 | 4 |
| PLCL2 | NRROS | 0.694195 | 5 | 0 | 5 |
| PLCL2 | CR1 | 0.68603 | 3 | 0 | 3 |
| PLCL2 | GLB1 | 0.684727 | 3 | 0 | 3 |
| PLCL2 | CD28 | 0.684286 | 4 | 0 | 3 |
| PLCL2 | MS4A4E | 0.68278 | 3 | 0 | 3 |
| PLCL2 | FGD5 | 0.68117 | 5 | 0 | 5 |
| PLCL2 | TMEM176B | 0.671048 | 10 | 0 | 8 |
| PLCL2 | NPR2 | 0.667649 | 4 | 0 | 3 |
| PLCL2 | ATP8B4 | 0.665288 | 8 | 0 | 7 |
| PLCL2 | ADAM28 | 0.662277 | 3 | 0 | 3 |
| PLCL2 | DOCK2 | 0.661999 | 11 | 0 | 9 |
| PLCL2 | EBI3 | 0.658963 | 5 | 0 | 4 |
| PLCL2 | CYTIP | 0.655325 | 8 | 0 | 7 |
| PLCL2 | CD48 | 0.653405 | 9 | 0 | 7 |
| PLCL2 | SH2D1A | 0.650085 | 5 | 0 | 4 |
| PLCL2 | NAT14 | 0.649746 | 3 | 0 | 3 |
| PLCL2 | SHC3 | 0.645257 | 4 | 0 | 3 |
For details and further investigation, click here
