| Full name: zinc finger SWIM-type containing 7 | Alias Symbol: SWS1 | ||
| Type: protein-coding gene | Cytoband: 17p12 | ||
| Entrez ID: 125150 | HGNC ID: HGNC:26993 | Ensembl Gene: ENSG00000214941 | OMIM ID: 614535 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of ZSWIM7:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZSWIM7 | 125150 | 229119_s_at | -0.2486 | 0.6685 | |
| GSE26886 | ZSWIM7 | 125150 | 229119_s_at | 0.6303 | 0.0510 | |
| GSE45670 | ZSWIM7 | 125150 | 229119_s_at | -0.1987 | 0.3716 | |
| GSE53622 | ZSWIM7 | 125150 | 39336 | -0.3254 | 0.0001 | |
| GSE53624 | ZSWIM7 | 125150 | 11810 | -0.1643 | 0.0526 | |
| GSE63941 | ZSWIM7 | 125150 | 229119_s_at | -0.2176 | 0.8261 | |
| GSE77861 | ZSWIM7 | 125150 | 229119_s_at | 0.0871 | 0.8993 | |
| GSE97050 | ZSWIM7 | 125150 | A_33_P3269723 | 0.0922 | 0.6565 | |
| SRP007169 | ZSWIM7 | 125150 | RNAseq | -0.4041 | 0.4239 | |
| SRP008496 | ZSWIM7 | 125150 | RNAseq | 0.1862 | 0.6476 | |
| SRP064894 | ZSWIM7 | 125150 | RNAseq | 0.7745 | 0.0083 | |
| SRP133303 | ZSWIM7 | 125150 | RNAseq | 0.0439 | 0.6974 | |
| SRP159526 | ZSWIM7 | 125150 | RNAseq | 0.1807 | 0.4185 | |
| SRP193095 | ZSWIM7 | 125150 | RNAseq | 0.0725 | 0.5121 | |
| SRP219564 | ZSWIM7 | 125150 | RNAseq | 0.2135 | 0.5689 | |
| TCGA | ZSWIM7 | 125150 | RNAseq | -0.0294 | 0.6695 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ZSWIM7 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ZSWIM7:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZSWIM7 | 125150 | 3 | 3 | 24 | |
| GSE20123 | ZSWIM7 | 125150 | 3 | 4 | 23 | |
| GSE43470 | ZSWIM7 | 125150 | 2 | 5 | 36 | |
| GSE46452 | ZSWIM7 | 125150 | 34 | 1 | 24 | |
| GSE47630 | ZSWIM7 | 125150 | 7 | 1 | 32 | |
| GSE54993 | ZSWIM7 | 125150 | 3 | 3 | 64 | |
| GSE54994 | ZSWIM7 | 125150 | 6 | 5 | 42 | |
| GSE60625 | ZSWIM7 | 125150 | 4 | 0 | 7 | |
| GSE74703 | ZSWIM7 | 125150 | 2 | 2 | 32 | |
| GSE74704 | ZSWIM7 | 125150 | 2 | 1 | 17 | |
| TCGA | ZSWIM7 | 125150 | 18 | 22 | 56 |
Total number of gains: 84; Total number of losses: 47; Total Number of normals: 357.
Somatic mutations of ZSWIM7:
Generating mutation plots.
Highly correlated genes for ZSWIM7:
Showing top 20/71 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZSWIM7 | VBP1 | 0.679441 | 3 | 0 | 3 |
| ZSWIM7 | ZNF747 | 0.661985 | 3 | 0 | 3 |
| ZSWIM7 | POLR3C | 0.647132 | 3 | 0 | 3 |
| ZSWIM7 | MTX3 | 0.638392 | 3 | 0 | 3 |
| ZSWIM7 | CENPH | 0.633518 | 3 | 0 | 3 |
| ZSWIM7 | GPHN | 0.630419 | 3 | 0 | 3 |
| ZSWIM7 | KBTBD3 | 0.624535 | 3 | 0 | 3 |
| ZSWIM7 | TTC19 | 0.612116 | 5 | 0 | 3 |
| ZSWIM7 | ZSWIM5 | 0.611475 | 4 | 0 | 3 |
| ZSWIM7 | ZNF627 | 0.611164 | 4 | 0 | 4 |
| ZSWIM7 | TTC8 | 0.610465 | 3 | 0 | 3 |
| ZSWIM7 | NOL9 | 0.610239 | 3 | 0 | 3 |
| ZSWIM7 | PIGH | 0.608571 | 3 | 0 | 3 |
| ZSWIM7 | RTN2 | 0.608054 | 3 | 0 | 3 |
| ZSWIM7 | UGP2 | 0.606635 | 3 | 0 | 3 |
| ZSWIM7 | PCID2 | 0.604349 | 3 | 0 | 3 |
| ZSWIM7 | CGRRF1 | 0.599617 | 3 | 0 | 3 |
| ZSWIM7 | SCAI | 0.593903 | 4 | 0 | 3 |
| ZSWIM7 | BOD1 | 0.593498 | 3 | 0 | 3 |
| ZSWIM7 | SMCR8 | 0.592843 | 3 | 0 | 3 |
For details and further investigation, click here
