| Full name: RNA polymerase III subunit C | Alias Symbol: RPC62|RPC3 | ||
| Type: protein-coding gene | Cytoband: 1q21.1 | ||
| Entrez ID: 10623 | HGNC ID: HGNC:30076 | Ensembl Gene: ENSG00000186141 | OMIM ID: 617454 |
| Drug and gene relationship at DGIdb | |||
Expression of POLR3C:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | POLR3C | 10623 | 209382_at | 0.0963 | 0.8716 | |
| GSE20347 | POLR3C | 10623 | 209382_at | 0.0809 | 0.5928 | |
| GSE23400 | POLR3C | 10623 | 210573_s_at | 0.0925 | 0.0186 | |
| GSE26886 | POLR3C | 10623 | 209382_at | 0.4508 | 0.0336 | |
| GSE29001 | POLR3C | 10623 | 209382_at | 0.2130 | 0.6151 | |
| GSE38129 | POLR3C | 10623 | 209382_at | 0.1713 | 0.1398 | |
| GSE45670 | POLR3C | 10623 | 209382_at | -0.0114 | 0.9237 | |
| GSE53622 | POLR3C | 10623 | 163188 | -0.0301 | 0.6162 | |
| GSE53624 | POLR3C | 10623 | 5241 | 0.1420 | 0.0092 | |
| GSE63941 | POLR3C | 10623 | 209382_at | -0.2085 | 0.7074 | |
| GSE77861 | POLR3C | 10623 | 210573_s_at | 0.1226 | 0.6474 | |
| GSE97050 | POLR3C | 10623 | A_23_P35256 | 0.0295 | 0.9250 | |
| SRP007169 | POLR3C | 10623 | RNAseq | -0.1972 | 0.5930 | |
| SRP008496 | POLR3C | 10623 | RNAseq | 0.2624 | 0.4086 | |
| SRP064894 | POLR3C | 10623 | RNAseq | 0.2044 | 0.1844 | |
| SRP133303 | POLR3C | 10623 | RNAseq | 0.1672 | 0.2302 | |
| SRP159526 | POLR3C | 10623 | RNAseq | 0.1968 | 0.2290 | |
| SRP193095 | POLR3C | 10623 | RNAseq | 0.1136 | 0.1329 | |
| SRP219564 | POLR3C | 10623 | RNAseq | 0.2184 | 0.5302 | |
| TCGA | POLR3C | 10623 | RNAseq | 0.0762 | 0.1626 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by POLR3C expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of POLR3C:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | POLR3C | 10623 | 12 | 0 | 18 | |
| GSE20123 | POLR3C | 10623 | 12 | 0 | 18 | |
| GSE43470 | POLR3C | 10623 | 5 | 1 | 37 | |
| GSE46452 | POLR3C | 10623 | 2 | 1 | 56 | |
| GSE47630 | POLR3C | 10623 | 12 | 2 | 26 | |
| GSE54993 | POLR3C | 10623 | 0 | 2 | 68 | |
| GSE54994 | POLR3C | 10623 | 15 | 0 | 38 | |
| GSE60625 | POLR3C | 10623 | 0 | 0 | 11 | |
| GSE74703 | POLR3C | 10623 | 5 | 1 | 30 | |
| GSE74704 | POLR3C | 10623 | 6 | 0 | 14 | |
| TCGA | POLR3C | 10623 | 33 | 15 | 48 |
Total number of gains: 102; Total number of losses: 22; Total Number of normals: 364.
Somatic mutations of POLR3C:
Generating mutation plots.
Highly correlated genes for POLR3C:
Showing top 20/693 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| POLR3C | ELF2 | 0.823383 | 3 | 0 | 3 |
| POLR3C | PPWD1 | 0.791712 | 3 | 0 | 3 |
| POLR3C | GTPBP6 | 0.790651 | 3 | 0 | 3 |
| POLR3C | CDKN2C | 0.786338 | 3 | 0 | 3 |
| POLR3C | NAA30 | 0.781758 | 3 | 0 | 3 |
| POLR3C | ABCB10 | 0.778454 | 3 | 0 | 3 |
| POLR3C | RNF13 | 0.765224 | 3 | 0 | 3 |
| POLR3C | C20orf194 | 0.764685 | 3 | 0 | 3 |
| POLR3C | SGMS1 | 0.759719 | 3 | 0 | 3 |
| POLR3C | TGFBRAP1 | 0.757486 | 4 | 0 | 4 |
| POLR3C | PSMG2 | 0.756728 | 3 | 0 | 3 |
| POLR3C | ZNF765 | 0.756577 | 3 | 0 | 3 |
| POLR3C | SFSWAP | 0.754781 | 3 | 0 | 3 |
| POLR3C | ZFP3 | 0.752041 | 3 | 0 | 3 |
| POLR3C | LRRC58 | 0.748484 | 3 | 0 | 3 |
| POLR3C | ING2 | 0.748442 | 3 | 0 | 3 |
| POLR3C | CEBPG | 0.741333 | 3 | 0 | 3 |
| POLR3C | KLHDC2 | 0.737995 | 5 | 0 | 5 |
| POLR3C | NOM1 | 0.737346 | 3 | 0 | 3 |
| POLR3C | FNTA | 0.733923 | 3 | 0 | 3 |
For details and further investigation, click here
