| Full name: metaxin 3 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 5q14.1 | ||
| Entrez ID: 345778 | HGNC ID: HGNC:24812 | Ensembl Gene: ENSG00000177034 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of MTX3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MTX3 | 345778 | 226528_at | -0.0347 | 0.9539 | |
| GSE26886 | MTX3 | 345778 | 226528_at | -0.0598 | 0.8831 | |
| GSE45670 | MTX3 | 345778 | 226528_at | -0.0635 | 0.7494 | |
| GSE53622 | MTX3 | 345778 | 81150 | 0.0409 | 0.5833 | |
| GSE53624 | MTX3 | 345778 | 81150 | 0.1898 | 0.0065 | |
| GSE63941 | MTX3 | 345778 | 226528_at | -0.6080 | 0.2064 | |
| GSE77861 | MTX3 | 345778 | 226528_at | 0.1145 | 0.7421 | |
| GSE97050 | MTX3 | 345778 | A_33_P3356846 | 0.0422 | 0.8681 | |
| SRP007169 | MTX3 | 345778 | RNAseq | 1.2529 | 0.0009 | |
| SRP008496 | MTX3 | 345778 | RNAseq | 1.1199 | 0.0000 | |
| SRP064894 | MTX3 | 345778 | RNAseq | 0.0619 | 0.7839 | |
| SRP133303 | MTX3 | 345778 | RNAseq | 0.3066 | 0.0942 | |
| SRP159526 | MTX3 | 345778 | RNAseq | -0.1397 | 0.6062 | |
| SRP193095 | MTX3 | 345778 | RNAseq | -0.1861 | 0.0924 | |
| SRP219564 | MTX3 | 345778 | RNAseq | -0.2307 | 0.3607 | |
| TCGA | MTX3 | 345778 | RNAseq | -0.0632 | 0.2218 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by MTX3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MTX3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MTX3 | 345778 | 1 | 13 | 16 | |
| GSE20123 | MTX3 | 345778 | 1 | 13 | 16 | |
| GSE43470 | MTX3 | 345778 | 1 | 11 | 31 | |
| GSE46452 | MTX3 | 345778 | 0 | 28 | 31 | |
| GSE47630 | MTX3 | 345778 | 1 | 19 | 20 | |
| GSE54993 | MTX3 | 345778 | 8 | 1 | 61 | |
| GSE54994 | MTX3 | 345778 | 2 | 18 | 33 | |
| GSE60625 | MTX3 | 345778 | 0 | 0 | 11 | |
| GSE74703 | MTX3 | 345778 | 1 | 7 | 28 | |
| GSE74704 | MTX3 | 345778 | 1 | 6 | 13 | |
| TCGA | MTX3 | 345778 | 5 | 49 | 42 |
Total number of gains: 21; Total number of losses: 165; Total Number of normals: 302.
Somatic mutations of MTX3:
Generating mutation plots.
Highly correlated genes for MTX3:
Showing top 20/295 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MTX3 | DHRS7 | 0.798963 | 4 | 0 | 4 |
| MTX3 | FHL2 | 0.786749 | 3 | 0 | 3 |
| MTX3 | MRFAP1L1 | 0.773663 | 3 | 0 | 3 |
| MTX3 | C6orf141 | 0.773196 | 3 | 0 | 3 |
| MTX3 | DPH3 | 0.766293 | 3 | 0 | 3 |
| MTX3 | CKAP2 | 0.766229 | 3 | 0 | 3 |
| MTX3 | CHD2 | 0.75863 | 3 | 0 | 3 |
| MTX3 | ASCC3 | 0.754506 | 3 | 0 | 3 |
| MTX3 | SCAPER | 0.730599 | 3 | 0 | 3 |
| MTX3 | RLIM | 0.730309 | 4 | 0 | 4 |
| MTX3 | C11orf54 | 0.72969 | 3 | 0 | 3 |
| MTX3 | MGAT2 | 0.72824 | 3 | 0 | 3 |
| MTX3 | CYB5R1 | 0.726081 | 3 | 0 | 3 |
| MTX3 | CIR1 | 0.720774 | 3 | 0 | 3 |
| MTX3 | RAB11FIP5 | 0.717661 | 3 | 0 | 3 |
| MTX3 | SLC39A9 | 0.715962 | 3 | 0 | 3 |
| MTX3 | PLEKHA8 | 0.709783 | 3 | 0 | 3 |
| MTX3 | INVS | 0.707706 | 3 | 0 | 3 |
| MTX3 | ZNF655 | 0.707003 | 3 | 0 | 3 |
| MTX3 | KLF10 | 0.706882 | 3 | 0 | 3 |
For details and further investigation, click here
