| Full name: tetratricopeptide repeat domain 19 | Alias Symbol: FLJ20343|MGC19520 | ||
| Type: protein-coding gene | Cytoband: 17p12 | ||
| Entrez ID: 54902 | HGNC ID: HGNC:26006 | Ensembl Gene: ENSG00000011295 | OMIM ID: 613814 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of TTC19:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TTC19 | 54902 | 217964_at | -0.1437 | 0.7364 | |
| GSE20347 | TTC19 | 54902 | 217964_at | -0.2061 | 0.2345 | |
| GSE23400 | TTC19 | 54902 | 217964_at | 0.0838 | 0.3084 | |
| GSE26886 | TTC19 | 54902 | 217964_at | -0.4426 | 0.1326 | |
| GSE29001 | TTC19 | 54902 | 217964_at | -0.1309 | 0.5458 | |
| GSE38129 | TTC19 | 54902 | 217964_at | -0.0581 | 0.6830 | |
| GSE45670 | TTC19 | 54902 | 217964_at | -0.2824 | 0.0764 | |
| GSE53622 | TTC19 | 54902 | 94050 | -0.1854 | 0.0358 | |
| GSE53624 | TTC19 | 54902 | 67846 | -0.1720 | 0.0213 | |
| GSE63941 | TTC19 | 54902 | 217964_at | 0.4451 | 0.4733 | |
| GSE77861 | TTC19 | 54902 | 217964_at | 0.0205 | 0.9590 | |
| GSE97050 | TTC19 | 54902 | A_33_P3230738 | -0.5419 | 0.1204 | |
| SRP007169 | TTC19 | 54902 | RNAseq | -0.8792 | 0.0224 | |
| SRP008496 | TTC19 | 54902 | RNAseq | -0.5907 | 0.0160 | |
| SRP064894 | TTC19 | 54902 | RNAseq | -0.0845 | 0.6290 | |
| SRP133303 | TTC19 | 54902 | RNAseq | -0.1381 | 0.2177 | |
| SRP159526 | TTC19 | 54902 | RNAseq | 0.1680 | 0.4758 | |
| SRP193095 | TTC19 | 54902 | RNAseq | -0.1943 | 0.0297 | |
| SRP219564 | TTC19 | 54902 | RNAseq | 0.3788 | 0.3388 | |
| TCGA | TTC19 | 54902 | RNAseq | -0.1510 | 0.0034 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TTC19 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TTC19:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TTC19 | 54902 | 3 | 3 | 24 | |
| GSE20123 | TTC19 | 54902 | 3 | 4 | 23 | |
| GSE43470 | TTC19 | 54902 | 2 | 5 | 36 | |
| GSE46452 | TTC19 | 54902 | 34 | 1 | 24 | |
| GSE47630 | TTC19 | 54902 | 7 | 1 | 32 | |
| GSE54993 | TTC19 | 54902 | 3 | 3 | 64 | |
| GSE54994 | TTC19 | 54902 | 6 | 5 | 42 | |
| GSE60625 | TTC19 | 54902 | 4 | 0 | 7 | |
| GSE74703 | TTC19 | 54902 | 2 | 2 | 32 | |
| GSE74704 | TTC19 | 54902 | 2 | 1 | 17 | |
| TCGA | TTC19 | 54902 | 18 | 23 | 55 |
Total number of gains: 84; Total number of losses: 48; Total Number of normals: 356.
Somatic mutations of TTC19:
Generating mutation plots.
Highly correlated genes for TTC19:
Showing top 20/209 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TTC19 | PARP16 | 0.78679 | 3 | 0 | 3 |
| TTC19 | TCTN3 | 0.735582 | 3 | 0 | 3 |
| TTC19 | UBE4B | 0.729272 | 3 | 0 | 3 |
| TTC19 | PIGL | 0.707111 | 3 | 0 | 3 |
| TTC19 | DIS3L | 0.702844 | 3 | 0 | 3 |
| TTC19 | PEX2 | 0.698663 | 3 | 0 | 3 |
| TTC19 | MTMR12 | 0.697039 | 3 | 0 | 3 |
| TTC19 | ALDH1A1 | 0.696251 | 4 | 0 | 3 |
| TTC19 | CNOT6L | 0.690611 | 4 | 0 | 3 |
| TTC19 | SLC35A3 | 0.689512 | 3 | 0 | 3 |
| TTC19 | HNRNPA1 | 0.689227 | 3 | 0 | 3 |
| TTC19 | TMEM218 | 0.687919 | 4 | 0 | 4 |
| TTC19 | PTGER4 | 0.682941 | 3 | 0 | 3 |
| TTC19 | SLC25A30 | 0.677881 | 3 | 0 | 3 |
| TTC19 | NUDT21 | 0.6746 | 3 | 0 | 3 |
| TTC19 | HMG20A | 0.668142 | 3 | 0 | 3 |
| TTC19 | GNPTAB | 0.66578 | 3 | 0 | 3 |
| TTC19 | C9orf72 | 0.65996 | 4 | 0 | 4 |
| TTC19 | VDAC2 | 0.658031 | 3 | 0 | 3 |
| TTC19 | EID1 | 0.656087 | 3 | 0 | 3 |
For details and further investigation, click here
