| Full name: alpha-1,4-N-acetylglucosaminyltransferase | Alias Symbol: alpha4GnT | ||
| Type: protein-coding gene | Cytoband: 3q22.3 | ||
| Entrez ID: 51146 | HGNC ID: HGNC:17968 | Ensembl Gene: ENSG00000118017 | OMIM ID: 616709 |
| Drug and gene relationship at DGIdb | |||
Expression of A4GNT:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | A4GNT | 51146 | 221131_at | -0.1607 | 0.3235 | |
| GSE20347 | A4GNT | 51146 | 221131_at | -0.1683 | 0.0302 | |
| GSE23400 | A4GNT | 51146 | 221131_at | -0.1245 | 0.0000 | |
| GSE26886 | A4GNT | 51146 | 221131_at | -0.0440 | 0.6595 | |
| GSE29001 | A4GNT | 51146 | 221131_at | -0.2371 | 0.0859 | |
| GSE38129 | A4GNT | 51146 | 221131_at | -0.2703 | 0.0000 | |
| GSE45670 | A4GNT | 51146 | 221131_at | -0.0223 | 0.8615 | |
| GSE53622 | A4GNT | 51146 | 10662 | -0.5273 | 0.0159 | |
| GSE53624 | A4GNT | 51146 | 10662 | -0.8726 | 0.0000 | |
| GSE63941 | A4GNT | 51146 | 221131_at | -0.0238 | 0.8982 | |
| GSE77861 | A4GNT | 51146 | 221131_at | -0.1005 | 0.3009 | |
| TCGA | A4GNT | 51146 | RNAseq | -2.9620 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by A4GNT expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of A4GNT:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | A4GNT | 51146 | 17 | 0 | 13 | |
| GSE20123 | A4GNT | 51146 | 17 | 0 | 13 | |
| GSE43470 | A4GNT | 51146 | 21 | 0 | 22 | |
| GSE46452 | A4GNT | 51146 | 15 | 4 | 40 | |
| GSE47630 | A4GNT | 51146 | 18 | 3 | 19 | |
| GSE54993 | A4GNT | 51146 | 2 | 8 | 60 | |
| GSE54994 | A4GNT | 51146 | 31 | 2 | 20 | |
| GSE60625 | A4GNT | 51146 | 0 | 6 | 5 | |
| GSE74703 | A4GNT | 51146 | 18 | 0 | 18 | |
| GSE74704 | A4GNT | 51146 | 11 | 0 | 9 | |
| TCGA | A4GNT | 51146 | 61 | 4 | 31 |
Total number of gains: 211; Total number of losses: 27; Total Number of normals: 250.
Somatic mutations of A4GNT:
Generating mutation plots.
Highly correlated genes for A4GNT:
Showing top 20/682 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| A4GNT | HRH2 | 0.69739 | 3 | 0 | 3 |
| A4GNT | AQP2 | 0.691527 | 3 | 0 | 3 |
| A4GNT | ATRNL1 | 0.687378 | 3 | 0 | 3 |
| A4GNT | GPR17 | 0.681038 | 3 | 0 | 3 |
| A4GNT | SERPINA4 | 0.674905 | 7 | 0 | 7 |
| A4GNT | NR1H4 | 0.671907 | 4 | 0 | 4 |
| A4GNT | F2 | 0.667104 | 3 | 0 | 3 |
| A4GNT | SMIM6 | 0.654137 | 3 | 0 | 3 |
| A4GNT | VWA7 | 0.651021 | 7 | 0 | 6 |
| A4GNT | SPX | 0.649637 | 5 | 0 | 3 |
| A4GNT | SLC29A3 | 0.647119 | 3 | 0 | 3 |
| A4GNT | KNG1 | 0.64413 | 4 | 0 | 3 |
| A4GNT | XPNPEP2 | 0.643986 | 6 | 0 | 5 |
| A4GNT | AP4S1 | 0.643275 | 4 | 0 | 4 |
| A4GNT | INO80D | 0.642427 | 5 | 0 | 4 |
| A4GNT | PHLDB1 | 0.64167 | 7 | 0 | 5 |
| A4GNT | TM4SF5 | 0.641346 | 6 | 0 | 5 |
| A4GNT | TSPAN32 | 0.634813 | 4 | 0 | 3 |
| A4GNT | MUC5AC | 0.634784 | 7 | 0 | 6 |
| A4GNT | ABCG4 | 0.634678 | 4 | 0 | 4 |
For details and further investigation, click here
