| Full name: shisa family member 3 | Alias Symbol: hShisa3 | ||
| Type: protein-coding gene | Cytoband: 4p13 | ||
| Entrez ID: 152573 | HGNC ID: HGNC:25159 | Ensembl Gene: ENSG00000178343 | OMIM ID: 617325 |
| Drug and gene relationship at DGIdb | |||
Expression of SHISA3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SHISA3 | 152573 | 229485_x_at | -1.0736 | 0.3581 | |
| GSE26886 | SHISA3 | 152573 | 229485_x_at | 0.1195 | 0.1638 | |
| GSE45670 | SHISA3 | 152573 | 229485_x_at | -1.3141 | 0.0005 | |
| GSE53622 | SHISA3 | 152573 | 22767 | -2.4514 | 0.0000 | |
| GSE53624 | SHISA3 | 152573 | 22767 | -2.3204 | 0.0000 | |
| GSE63941 | SHISA3 | 152573 | 229485_x_at | -4.9116 | 0.0000 | |
| GSE77861 | SHISA3 | 152573 | 229485_x_at | 0.0046 | 0.9572 | |
| GSE97050 | SHISA3 | 152573 | A_23_P41476 | -0.6292 | 0.2546 | |
| SRP133303 | SHISA3 | 152573 | RNAseq | -1.3350 | 0.0724 | |
| SRP159526 | SHISA3 | 152573 | RNAseq | -0.0424 | 0.9641 | |
| TCGA | SHISA3 | 152573 | RNAseq | -2.0980 | 0.0004 |
Upregulated datasets: 0; Downregulated datasets: 5.
Survival by SHISA3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SHISA3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SHISA3 | 152573 | 0 | 16 | 14 | |
| GSE20123 | SHISA3 | 152573 | 0 | 16 | 14 | |
| GSE43470 | SHISA3 | 152573 | 0 | 14 | 29 | |
| GSE46452 | SHISA3 | 152573 | 1 | 36 | 22 | |
| GSE47630 | SHISA3 | 152573 | 1 | 18 | 21 | |
| GSE54993 | SHISA3 | 152573 | 7 | 0 | 63 | |
| GSE54994 | SHISA3 | 152573 | 4 | 9 | 40 | |
| GSE60625 | SHISA3 | 152573 | 0 | 0 | 11 | |
| GSE74703 | SHISA3 | 152573 | 0 | 12 | 24 | |
| GSE74704 | SHISA3 | 152573 | 0 | 9 | 11 | |
| TCGA | SHISA3 | 152573 | 12 | 41 | 43 |
Total number of gains: 25; Total number of losses: 171; Total Number of normals: 292.
Somatic mutations of SHISA3:
Generating mutation plots.
Highly correlated genes for SHISA3:
Showing top 20/429 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SHISA3 | MGARP | 0.857256 | 3 | 0 | 3 |
| SHISA3 | ABCA6 | 0.844237 | 5 | 0 | 5 |
| SHISA3 | SORCS1 | 0.838465 | 3 | 0 | 3 |
| SHISA3 | ITGBL1 | 0.829783 | 3 | 0 | 3 |
| SHISA3 | TMEM100 | 0.803659 | 6 | 0 | 6 |
| SHISA3 | RSPO2 | 0.803192 | 3 | 0 | 3 |
| SHISA3 | PCDH9 | 0.802317 | 4 | 0 | 4 |
| SHISA3 | BHMT2 | 0.79042 | 5 | 0 | 5 |
| SHISA3 | CACNA1C | 0.778962 | 4 | 0 | 4 |
| SHISA3 | ASPA | 0.77842 | 5 | 0 | 5 |
| SHISA3 | PLCXD3 | 0.772705 | 4 | 0 | 4 |
| SHISA3 | MYOC | 0.768355 | 5 | 0 | 4 |
| SHISA3 | COX7A1 | 0.760932 | 5 | 0 | 5 |
| SHISA3 | CBX7 | 0.760497 | 4 | 0 | 4 |
| SHISA3 | ZNF582 | 0.7563 | 4 | 0 | 4 |
| SHISA3 | ARHGAP20 | 0.755207 | 3 | 0 | 3 |
| SHISA3 | FGL2 | 0.754918 | 5 | 0 | 5 |
| SHISA3 | PABPC5 | 0.750515 | 5 | 0 | 5 |
| SHISA3 | ALDH8A1 | 0.75017 | 3 | 0 | 3 |
| SHISA3 | IL6ST | 0.74902 | 5 | 0 | 5 |
For details and further investigation, click here
