| Full name: phosphatidylinositol specific phospholipase C X domain containing 3 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 5p13.1 | ||
| Entrez ID: 345557 | HGNC ID: HGNC:31822 | Ensembl Gene: ENSG00000182836 | OMIM ID: 617016 |
| Drug and gene relationship at DGIdb | |||
Expression of PLCXD3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PLCXD3 | 345557 | 239270_at | -0.6633 | 0.0777 | |
| GSE26886 | PLCXD3 | 345557 | 239270_at | -0.0649 | 0.6267 | |
| GSE45670 | PLCXD3 | 345557 | 239270_at | -0.6635 | 0.0004 | |
| GSE53622 | PLCXD3 | 345557 | 23386 | -3.1176 | 0.0000 | |
| GSE53624 | PLCXD3 | 345557 | 23386 | -3.6016 | 0.0000 | |
| GSE63941 | PLCXD3 | 345557 | 239270_at | 0.0839 | 0.5925 | |
| GSE77861 | PLCXD3 | 345557 | 239270_at | -0.1237 | 0.3170 | |
| SRP133303 | PLCXD3 | 345557 | RNAseq | -1.2467 | 0.0000 | |
| SRP159526 | PLCXD3 | 345557 | RNAseq | -1.4296 | 0.0085 | |
| SRP219564 | PLCXD3 | 345557 | RNAseq | -0.7289 | 0.3198 | |
| TCGA | PLCXD3 | 345557 | RNAseq | -3.3689 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 5.
Survival by PLCXD3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PLCXD3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PLCXD3 | 345557 | 9 | 0 | 21 | |
| GSE20123 | PLCXD3 | 345557 | 9 | 0 | 21 | |
| GSE43470 | PLCXD3 | 345557 | 17 | 0 | 26 | |
| GSE46452 | PLCXD3 | 345557 | 5 | 22 | 32 | |
| GSE47630 | PLCXD3 | 345557 | 6 | 12 | 22 | |
| GSE54993 | PLCXD3 | 345557 | 6 | 3 | 61 | |
| GSE54994 | PLCXD3 | 345557 | 24 | 2 | 27 | |
| GSE60625 | PLCXD3 | 345557 | 0 | 0 | 11 | |
| GSE74703 | PLCXD3 | 345557 | 13 | 0 | 23 | |
| GSE74704 | PLCXD3 | 345557 | 8 | 0 | 12 | |
| TCGA | PLCXD3 | 345557 | 53 | 6 | 37 |
Total number of gains: 150; Total number of losses: 45; Total Number of normals: 293.
Somatic mutations of PLCXD3:
Generating mutation plots.
Highly correlated genes for PLCXD3:
Showing top 20/715 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PLCXD3 | TMEM100 | 0.862151 | 4 | 0 | 4 |
| PLCXD3 | FAM107A | 0.845878 | 4 | 0 | 4 |
| PLCXD3 | MYRIP | 0.821801 | 5 | 0 | 5 |
| PLCXD3 | ADH1B | 0.817918 | 4 | 0 | 4 |
| PLCXD3 | ABCA6 | 0.808925 | 4 | 0 | 4 |
| PLCXD3 | RCAN2 | 0.808509 | 4 | 0 | 4 |
| PLCXD3 | FHL5 | 0.806781 | 4 | 0 | 4 |
| PLCXD3 | IL6ST | 0.802206 | 4 | 0 | 4 |
| PLCXD3 | CMA1 | 0.798031 | 4 | 0 | 4 |
| PLCXD3 | NDNF | 0.790985 | 4 | 0 | 4 |
| PLCXD3 | ATP1A2 | 0.790475 | 4 | 0 | 4 |
| PLCXD3 | LGI1 | 0.790187 | 4 | 0 | 4 |
| PLCXD3 | RECK | 0.789776 | 3 | 0 | 3 |
| PLCXD3 | APOD | 0.786768 | 4 | 0 | 4 |
| PLCXD3 | ITM2A | 0.786185 | 4 | 0 | 4 |
| PLCXD3 | ITGA8 | 0.785704 | 4 | 0 | 4 |
| PLCXD3 | RSPO2 | 0.780365 | 3 | 0 | 3 |
| PLCXD3 | METTL7A | 0.77601 | 4 | 0 | 4 |
| PLCXD3 | CHRDL1 | 0.774952 | 3 | 0 | 3 |
| PLCXD3 | SHISA3 | 0.772705 | 4 | 0 | 4 |
For details and further investigation, click here
