| Full name: ATP binding cassette subfamily B member 5 | Alias Symbol: EST422562|ABCB5beta|ABCB5alpha | ||
| Type: protein-coding gene | Cytoband: 7p21.1 | ||
| Entrez ID: 340273 | HGNC ID: HGNC:46 | Ensembl Gene: ENSG00000004846 | OMIM ID: 611785 |
| Drug and gene relationship at DGIdb | |||
Expression of ABCB5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ABCB5 | 340273 | 1555371_at | -0.1072 | 0.6692 | |
| GSE26886 | ABCB5 | 340273 | 1555371_at | 0.0263 | 0.8448 | |
| GSE45670 | ABCB5 | 340273 | 1555371_at | 0.1526 | 0.0996 | |
| GSE53622 | ABCB5 | 340273 | 41114 | 0.1067 | 0.6012 | |
| GSE53624 | ABCB5 | 340273 | 41114 | 0.4998 | 0.0000 | |
| GSE63941 | ABCB5 | 340273 | 1555371_at | 0.0626 | 0.7081 | |
| GSE77861 | ABCB5 | 340273 | 1555371_at | -0.0413 | 0.6679 | |
| GSE97050 | ABCB5 | 340273 | A_33_P3337554 | -0.0352 | 0.8652 | |
| SRP133303 | ABCB5 | 340273 | RNAseq | 0.0418 | 0.8368 | |
| SRP159526 | ABCB5 | 340273 | RNAseq | 0.4854 | 0.4699 | |
| SRP193095 | ABCB5 | 340273 | RNAseq | 0.1630 | 0.3761 | |
| TCGA | ABCB5 | 340273 | RNAseq | -0.5198 | 0.4956 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ABCB5 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ABCB5:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ABCB5 | 340273 | 16 | 2 | 12 | |
| GSE20123 | ABCB5 | 340273 | 16 | 2 | 12 | |
| GSE43470 | ABCB5 | 340273 | 4 | 0 | 39 | |
| GSE46452 | ABCB5 | 340273 | 10 | 2 | 47 | |
| GSE47630 | ABCB5 | 340273 | 9 | 1 | 30 | |
| GSE54993 | ABCB5 | 340273 | 0 | 6 | 64 | |
| GSE54994 | ABCB5 | 340273 | 20 | 2 | 31 | |
| GSE60625 | ABCB5 | 340273 | 0 | 0 | 11 | |
| GSE74703 | ABCB5 | 340273 | 4 | 0 | 32 | |
| GSE74704 | ABCB5 | 340273 | 10 | 2 | 8 | |
| TCGA | ABCB5 | 340273 | 56 | 5 | 35 |
Total number of gains: 145; Total number of losses: 22; Total Number of normals: 321.
Somatic mutations of ABCB5:
Generating mutation plots.
Highly correlated genes for ABCB5:
Showing top 20/69 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ABCB5 | UROC1 | 0.738979 | 3 | 0 | 3 |
| ABCB5 | TEX22 | 0.703071 | 3 | 0 | 3 |
| ABCB5 | FSCN3 | 0.693179 | 4 | 0 | 3 |
| ABCB5 | PRRG3 | 0.692392 | 3 | 0 | 3 |
| ABCB5 | KRTAP4-8 | 0.683008 | 3 | 0 | 3 |
| ABCB5 | SLC12A3 | 0.677364 | 3 | 0 | 3 |
| ABCB5 | CLEC1B | 0.676301 | 4 | 0 | 3 |
| ABCB5 | MMP21 | 0.674636 | 3 | 0 | 3 |
| ABCB5 | LGALS14 | 0.668988 | 3 | 0 | 3 |
| ABCB5 | GALNTL5 | 0.665866 | 3 | 0 | 3 |
| ABCB5 | CNPY1 | 0.664031 | 3 | 0 | 3 |
| ABCB5 | LCT | 0.659504 | 4 | 0 | 3 |
| ABCB5 | TDRD1 | 0.657445 | 3 | 0 | 3 |
| ABCB5 | DEFA4 | 0.63848 | 3 | 0 | 3 |
| ABCB5 | C14orf180 | 0.63777 | 4 | 0 | 3 |
| ABCB5 | OLIG3 | 0.636059 | 3 | 0 | 3 |
| ABCB5 | FCAMR | 0.634907 | 3 | 0 | 3 |
| ABCB5 | NRSN1 | 0.634365 | 3 | 0 | 3 |
| ABCB5 | C22orf23 | 0.632582 | 5 | 0 | 4 |
| ABCB5 | SLC24A2 | 0.629724 | 3 | 0 | 3 |
For details and further investigation, click here
