| Full name: ATP binding cassette subfamily C member 11 | Alias Symbol: MRP8 | ||
| Type: protein-coding gene | Cytoband: 16q12.1 | ||
| Entrez ID: 85320 | HGNC ID: HGNC:14639 | Ensembl Gene: ENSG00000121270 | OMIM ID: 607040 |
| Drug and gene relationship at DGIdb | |||
Expression of ABCC11:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ABCC11 | 85320 | 1554911_at | -0.1094 | 0.7130 | |
| GSE26886 | ABCC11 | 85320 | 1554911_at | -0.2246 | 0.0945 | |
| GSE45670 | ABCC11 | 85320 | 1554911_at | 0.1578 | 0.1734 | |
| GSE53622 | ABCC11 | 85320 | 71724 | 0.2165 | 0.3576 | |
| GSE53624 | ABCC11 | 85320 | 88448 | 0.0779 | 0.3762 | |
| GSE63941 | ABCC11 | 85320 | 1554911_at | 0.2163 | 0.1338 | |
| GSE77861 | ABCC11 | 85320 | 1554911_at | -0.2541 | 0.0759 | |
| SRP133303 | ABCC11 | 85320 | RNAseq | 0.4448 | 0.0257 | |
| SRP159526 | ABCC11 | 85320 | RNAseq | 0.3213 | 0.5204 | |
| SRP193095 | ABCC11 | 85320 | RNAseq | 0.1872 | 0.1902 | |
| SRP219564 | ABCC11 | 85320 | RNAseq | -0.2075 | 0.6884 | |
| TCGA | ABCC11 | 85320 | RNAseq | 2.3072 | 0.0000 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by ABCC11 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ABCC11:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ABCC11 | 85320 | 2 | 1 | 27 | |
| GSE20123 | ABCC11 | 85320 | 2 | 1 | 27 | |
| GSE43470 | ABCC11 | 85320 | 2 | 7 | 34 | |
| GSE46452 | ABCC11 | 85320 | 38 | 1 | 20 | |
| GSE47630 | ABCC11 | 85320 | 11 | 7 | 22 | |
| GSE54993 | ABCC11 | 85320 | 2 | 5 | 63 | |
| GSE54994 | ABCC11 | 85320 | 6 | 10 | 37 | |
| GSE60625 | ABCC11 | 85320 | 4 | 0 | 7 | |
| GSE74703 | ABCC11 | 85320 | 2 | 4 | 30 | |
| GSE74704 | ABCC11 | 85320 | 2 | 1 | 17 | |
| TCGA | ABCC11 | 85320 | 29 | 11 | 56 |
Total number of gains: 100; Total number of losses: 48; Total Number of normals: 340.
Somatic mutations of ABCC11:
Generating mutation plots.
Highly correlated genes for ABCC11:
Showing top 20/69 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ABCC11 | SCOC-AS1 | 0.676809 | 3 | 0 | 3 |
| ABCC11 | ANHX | 0.649417 | 3 | 0 | 3 |
| ABCC11 | KNCN | 0.632756 | 4 | 0 | 4 |
| ABCC11 | CYP4A11 | 0.621347 | 3 | 0 | 3 |
| ABCC11 | SPINT3 | 0.621306 | 3 | 0 | 3 |
| ABCC11 | ALB | 0.61938 | 3 | 0 | 3 |
| ABCC11 | LUZP2 | 0.611381 | 4 | 0 | 3 |
| ABCC11 | CAV3 | 0.607084 | 3 | 0 | 3 |
| ABCC11 | CNR2 | 0.60309 | 4 | 0 | 3 |
| ABCC11 | LINC01119 | 0.60137 | 3 | 0 | 3 |
| ABCC11 | LINC00689 | 0.597869 | 5 | 0 | 3 |
| ABCC11 | NUTM1 | 0.592201 | 5 | 0 | 3 |
| ABCC11 | NMUR2 | 0.589477 | 4 | 0 | 3 |
| ABCC11 | TAGAP | 0.577032 | 3 | 0 | 3 |
| ABCC11 | CD1A | 0.576837 | 4 | 0 | 3 |
| ABCC11 | ISX | 0.575062 | 4 | 0 | 3 |
| ABCC11 | OR4D2 | 0.573871 | 6 | 0 | 3 |
| ABCC11 | CCDC13 | 0.57237 | 5 | 0 | 4 |
| ABCC11 | SLC6A19 | 0.571532 | 4 | 0 | 3 |
| ABCC11 | LINC00824 | 0.571022 | 3 | 0 | 3 |
For details and further investigation, click here
