| Full name: CD1a molecule | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 1q23.1 | ||
| Entrez ID: 909 | HGNC ID: HGNC:1634 | Ensembl Gene: ENSG00000158477 | OMIM ID: 188370 |
| Drug and gene relationship at DGIdb | |||
Expression of CD1A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CD1A | 909 | 210325_at | -0.6858 | 0.4220 | |
| GSE20347 | CD1A | 909 | 210325_at | -0.9466 | 0.0000 | |
| GSE23400 | CD1A | 909 | 210325_at | -0.3046 | 0.0001 | |
| GSE26886 | CD1A | 909 | 210325_at | -2.2937 | 0.0000 | |
| GSE29001 | CD1A | 909 | 210325_at | -1.2371 | 0.0039 | |
| GSE38129 | CD1A | 909 | 210325_at | -0.7086 | 0.0017 | |
| GSE45670 | CD1A | 909 | 210325_at | -1.3232 | 0.0006 | |
| GSE53622 | CD1A | 909 | 52533 | -1.4404 | 0.0000 | |
| GSE53624 | CD1A | 909 | 52533 | -1.9814 | 0.0000 | |
| GSE63941 | CD1A | 909 | 210325_at | 0.4680 | 0.0084 | |
| GSE77861 | CD1A | 909 | 210325_at | -0.8508 | 0.0031 | |
| GSE97050 | CD1A | 909 | A_23_P402670 | -0.1642 | 0.7535 | |
| SRP007169 | CD1A | 909 | RNAseq | -2.9992 | 0.0000 | |
| SRP064894 | CD1A | 909 | RNAseq | -1.9055 | 0.0000 | |
| SRP133303 | CD1A | 909 | RNAseq | -1.7931 | 0.0000 | |
| SRP159526 | CD1A | 909 | RNAseq | -2.6580 | 0.0000 | |
| SRP219564 | CD1A | 909 | RNAseq | -1.6974 | 0.0617 | |
| TCGA | CD1A | 909 | RNAseq | 1.4602 | 0.0001 |
Upregulated datasets: 1; Downregulated datasets: 9.
Survival by CD1A expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CD1A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CD1A | 909 | 9 | 1 | 20 | |
| GSE20123 | CD1A | 909 | 9 | 1 | 20 | |
| GSE43470 | CD1A | 909 | 7 | 2 | 34 | |
| GSE46452 | CD1A | 909 | 2 | 1 | 56 | |
| GSE47630 | CD1A | 909 | 14 | 0 | 26 | |
| GSE54993 | CD1A | 909 | 0 | 5 | 65 | |
| GSE54994 | CD1A | 909 | 16 | 0 | 37 | |
| GSE60625 | CD1A | 909 | 0 | 0 | 11 | |
| GSE74703 | CD1A | 909 | 7 | 2 | 27 | |
| GSE74704 | CD1A | 909 | 4 | 1 | 15 | |
| TCGA | CD1A | 909 | 39 | 3 | 54 |
Total number of gains: 107; Total number of losses: 16; Total Number of normals: 365.
Somatic mutations of CD1A:
Generating mutation plots.
Highly correlated genes for CD1A:
Showing top 20/706 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CD1A | CD207 | 0.874784 | 10 | 0 | 10 |
| CD1A | BCDIN3D | 0.751519 | 3 | 0 | 3 |
| CD1A | HES5 | 0.741187 | 3 | 0 | 3 |
| CD1A | ASPG | 0.710952 | 5 | 0 | 5 |
| CD1A | NCCRP1 | 0.705815 | 3 | 0 | 3 |
| CD1A | CD1C | 0.700806 | 8 | 0 | 6 |
| CD1A | LINC00479 | 0.693677 | 3 | 0 | 3 |
| CD1A | BBOX1 | 0.692214 | 11 | 0 | 9 |
| CD1A | MUC22 | 0.690552 | 3 | 0 | 3 |
| CD1A | SH3BGRL2 | 0.685976 | 6 | 0 | 6 |
| CD1A | FAM163B | 0.680073 | 3 | 0 | 3 |
| CD1A | ST6GALNAC1 | 0.68006 | 6 | 0 | 6 |
| CD1A | HCG22 | 0.675885 | 6 | 0 | 6 |
| CD1A | RDH12 | 0.67366 | 5 | 0 | 5 |
| CD1A | KRT32 | 0.672727 | 10 | 0 | 10 |
| CD1A | KRT78 | 0.667784 | 6 | 0 | 6 |
| CD1A | FAM214A | 0.664788 | 6 | 0 | 6 |
| CD1A | BLNK | 0.664012 | 10 | 0 | 9 |
| CD1A | CXCR2 | 0.663265 | 10 | 0 | 9 |
| CD1A | SAMD5 | 0.663065 | 6 | 0 | 5 |
For details and further investigation, click here
