| Full name: ATP binding cassette subfamily D member 3 | Alias Symbol: PMP70|ZWS2 | ||
| Type: protein-coding gene | Cytoband: 1p21.3 | ||
| Entrez ID: 5825 | HGNC ID: HGNC:67 | Ensembl Gene: ENSG00000117528 | OMIM ID: 170995 |
| Drug and gene relationship at DGIdb | |||
Expression of ABCD3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ABCD3 | 5825 | 202850_at | -0.1879 | 0.7109 | |
| GSE20347 | ABCD3 | 5825 | 202850_at | -0.8395 | 0.0001 | |
| GSE23400 | ABCD3 | 5825 | 202850_at | -0.8011 | 0.0000 | |
| GSE26886 | ABCD3 | 5825 | 202850_at | -1.5924 | 0.0000 | |
| GSE29001 | ABCD3 | 5825 | 202850_at | -1.1243 | 0.0011 | |
| GSE38129 | ABCD3 | 5825 | 202850_at | -0.7073 | 0.0003 | |
| GSE45670 | ABCD3 | 5825 | 202850_at | -0.5739 | 0.0057 | |
| GSE53622 | ABCD3 | 5825 | 41711 | -0.6571 | 0.0000 | |
| GSE53624 | ABCD3 | 5825 | 78257 | 0.4432 | 0.0001 | |
| GSE63941 | ABCD3 | 5825 | 202850_at | -0.6018 | 0.2587 | |
| GSE77861 | ABCD3 | 5825 | 202850_at | -1.3332 | 0.0011 | |
| GSE97050 | ABCD3 | 5825 | A_33_P3307955 | 0.0533 | 0.8059 | |
| SRP007169 | ABCD3 | 5825 | RNAseq | -1.4387 | 0.0002 | |
| SRP008496 | ABCD3 | 5825 | RNAseq | -1.5723 | 0.0000 | |
| SRP064894 | ABCD3 | 5825 | RNAseq | -0.8869 | 0.0008 | |
| SRP133303 | ABCD3 | 5825 | RNAseq | -0.6519 | 0.0001 | |
| SRP159526 | ABCD3 | 5825 | RNAseq | -0.2241 | 0.6601 | |
| SRP193095 | ABCD3 | 5825 | RNAseq | -0.9578 | 0.0000 | |
| SRP219564 | ABCD3 | 5825 | RNAseq | -0.7051 | 0.1202 | |
| TCGA | ABCD3 | 5825 | RNAseq | -0.3664 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 5.
Survival by ABCD3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ABCD3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ABCD3 | 5825 | 0 | 8 | 22 | |
| GSE20123 | ABCD3 | 5825 | 0 | 8 | 22 | |
| GSE43470 | ABCD3 | 5825 | 2 | 6 | 35 | |
| GSE46452 | ABCD3 | 5825 | 1 | 1 | 57 | |
| GSE47630 | ABCD3 | 5825 | 8 | 5 | 27 | |
| GSE54993 | ABCD3 | 5825 | 0 | 1 | 69 | |
| GSE54994 | ABCD3 | 5825 | 6 | 3 | 44 | |
| GSE60625 | ABCD3 | 5825 | 0 | 0 | 11 | |
| GSE74703 | ABCD3 | 5825 | 1 | 5 | 30 | |
| GSE74704 | ABCD3 | 5825 | 0 | 5 | 15 | |
| TCGA | ABCD3 | 5825 | 6 | 24 | 66 |
Total number of gains: 24; Total number of losses: 66; Total Number of normals: 398.
Somatic mutations of ABCD3:
Generating mutation plots.
Highly correlated genes for ABCD3:
Showing top 20/397 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ABCD3 | SNORA68 | 0.794454 | 3 | 0 | 3 |
| ABCD3 | ETFDH | 0.769042 | 8 | 0 | 8 |
| ABCD3 | NCKAP5 | 0.764974 | 3 | 0 | 3 |
| ABCD3 | NICN1 | 0.763058 | 4 | 0 | 3 |
| ABCD3 | VSIG2 | 0.750421 | 5 | 0 | 5 |
| ABCD3 | FAM3D | 0.746951 | 5 | 0 | 5 |
| ABCD3 | PDZD2 | 0.745375 | 9 | 0 | 9 |
| ABCD3 | SH2D1B | 0.744428 | 4 | 0 | 3 |
| ABCD3 | UBL3 | 0.729793 | 9 | 0 | 8 |
| ABCD3 | KIAA1211L | 0.727419 | 5 | 0 | 5 |
| ABCD3 | FAM3B | 0.725181 | 5 | 0 | 5 |
| ABCD3 | CXCL17 | 0.723134 | 4 | 0 | 4 |
| ABCD3 | MACC1 | 0.722799 | 5 | 0 | 5 |
| ABCD3 | ZNF568 | 0.722679 | 4 | 0 | 4 |
| ABCD3 | B3GNT8 | 0.720841 | 4 | 0 | 4 |
| ABCD3 | CC2D1B | 0.715111 | 3 | 0 | 3 |
| ABCD3 | KRT78 | 0.713516 | 5 | 0 | 4 |
| ABCD3 | CYP2J2 | 0.712966 | 9 | 0 | 8 |
| ABCD3 | SLC6A18 | 0.71156 | 3 | 0 | 3 |
| ABCD3 | GYS2 | 0.704393 | 8 | 0 | 8 |
For details and further investigation, click here
