| Full name: NCK associated protein 5 | Alias Symbol: NAP5|ERIH1|ERIH2 | ||
| Type: protein-coding gene | Cytoband: 2q21.2 | ||
| Entrez ID: 344148 | HGNC ID: HGNC:29847 | Ensembl Gene: ENSG00000176771 | OMIM ID: 608789 |
| Drug and gene relationship at DGIdb | |||
Expression of NCKAP5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NCKAP5 | 344148 | 239650_at | -0.5517 | 0.6992 | |
| GSE26886 | NCKAP5 | 344148 | 239650_at | -1.8429 | 0.0000 | |
| GSE45670 | NCKAP5 | 344148 | 239650_at | -0.2547 | 0.5121 | |
| GSE53622 | NCKAP5 | 344148 | 97444 | -0.4444 | 0.0093 | |
| GSE53624 | NCKAP5 | 344148 | 97444 | -0.7763 | 0.0000 | |
| GSE63941 | NCKAP5 | 344148 | 239650_at | -3.6214 | 0.0001 | |
| GSE77861 | NCKAP5 | 344148 | 239650_at | -0.1421 | 0.4823 | |
| GSE97050 | NCKAP5 | 344148 | A_23_P360079 | -0.2207 | 0.5136 | |
| SRP064894 | NCKAP5 | 344148 | RNAseq | -0.7440 | 0.0364 | |
| SRP133303 | NCKAP5 | 344148 | RNAseq | -0.2288 | 0.4627 | |
| SRP159526 | NCKAP5 | 344148 | RNAseq | -0.6235 | 0.1910 | |
| SRP193095 | NCKAP5 | 344148 | RNAseq | -0.8200 | 0.0003 | |
| SRP219564 | NCKAP5 | 344148 | RNAseq | -0.8245 | 0.1032 | |
| TCGA | NCKAP5 | 344148 | RNAseq | 0.0034 | 0.9843 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by NCKAP5 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NCKAP5:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NCKAP5 | 344148 | 4 | 4 | 22 | |
| GSE20123 | NCKAP5 | 344148 | 4 | 4 | 22 | |
| GSE43470 | NCKAP5 | 344148 | 2 | 1 | 40 | |
| GSE46452 | NCKAP5 | 344148 | 1 | 4 | 54 | |
| GSE47630 | NCKAP5 | 344148 | 5 | 2 | 33 | |
| GSE54993 | NCKAP5 | 344148 | 0 | 6 | 64 | |
| GSE54994 | NCKAP5 | 344148 | 9 | 2 | 42 | |
| GSE60625 | NCKAP5 | 344148 | 0 | 3 | 8 | |
| GSE74703 | NCKAP5 | 344148 | 2 | 1 | 33 | |
| GSE74704 | NCKAP5 | 344148 | 2 | 2 | 16 | |
| TCGA | NCKAP5 | 344148 | 24 | 18 | 54 |
Total number of gains: 53; Total number of losses: 47; Total Number of normals: 388.
Somatic mutations of NCKAP5:
Generating mutation plots.
Highly correlated genes for NCKAP5:
Showing top 20/181 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NCKAP5 | PDZRN3 | 0.767052 | 4 | 0 | 4 |
| NCKAP5 | ABCD3 | 0.764974 | 3 | 0 | 3 |
| NCKAP5 | ABCB1 | 0.763955 | 3 | 0 | 3 |
| NCKAP5 | CES2 | 0.713223 | 3 | 0 | 3 |
| NCKAP5 | ERN1 | 0.71198 | 3 | 0 | 3 |
| NCKAP5 | MFSD1 | 0.697524 | 5 | 0 | 4 |
| NCKAP5 | MAPKAPK3 | 0.688402 | 4 | 0 | 3 |
| NCKAP5 | LDB2 | 0.687463 | 3 | 0 | 3 |
| NCKAP5 | YIPF1 | 0.680233 | 4 | 0 | 3 |
| NCKAP5 | MOS | 0.669999 | 3 | 0 | 3 |
| NCKAP5 | RABGGTB | 0.669589 | 3 | 0 | 3 |
| NCKAP5 | NRG4 | 0.666296 | 4 | 0 | 3 |
| NCKAP5 | TMEM134 | 0.664201 | 3 | 0 | 3 |
| NCKAP5 | ZDHHC15 | 0.662822 | 3 | 0 | 3 |
| NCKAP5 | ZNF667 | 0.662578 | 3 | 0 | 3 |
| NCKAP5 | SERINC5 | 0.660913 | 5 | 0 | 3 |
| NCKAP5 | SHOC2 | 0.660779 | 4 | 0 | 3 |
| NCKAP5 | TGM1 | 0.657182 | 4 | 0 | 3 |
| NCKAP5 | CNEP1R1 | 0.655298 | 3 | 0 | 3 |
| NCKAP5 | CYP2W1 | 0.655037 | 3 | 0 | 3 |
For details and further investigation, click here
