| Full name: PDZ domain containing 2 | Alias Symbol: KIAA0300 | ||
| Type: protein-coding gene | Cytoband: 5p13.3 | ||
| Entrez ID: 23037 | HGNC ID: HGNC:18486 | Ensembl Gene: ENSG00000133401 | OMIM ID: 610697 |
| Drug and gene relationship at DGIdb | |||
Expression of PDZD2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PDZD2 | 23037 | 209493_at | -0.6453 | 0.5401 | |
| GSE20347 | PDZD2 | 23037 | 209493_at | -1.9367 | 0.0000 | |
| GSE23400 | PDZD2 | 23037 | 209493_at | -1.6528 | 0.0000 | |
| GSE26886 | PDZD2 | 23037 | 209493_at | -3.1635 | 0.0000 | |
| GSE29001 | PDZD2 | 23037 | 209493_at | -2.0001 | 0.0004 | |
| GSE38129 | PDZD2 | 23037 | 209493_at | -1.9010 | 0.0000 | |
| GSE45670 | PDZD2 | 23037 | 209493_at | -1.1623 | 0.0034 | |
| GSE53622 | PDZD2 | 23037 | 152502 | -1.4245 | 0.0000 | |
| GSE53624 | PDZD2 | 23037 | 152502 | -1.8937 | 0.0000 | |
| GSE63941 | PDZD2 | 23037 | 209493_at | 0.1450 | 0.9310 | |
| GSE77861 | PDZD2 | 23037 | 209493_at | -2.0142 | 0.0052 | |
| GSE97050 | PDZD2 | 23037 | A_33_P3283515 | -0.2158 | 0.3673 | |
| SRP007169 | PDZD2 | 23037 | RNAseq | -4.0903 | 0.0000 | |
| SRP008496 | PDZD2 | 23037 | RNAseq | -3.4359 | 0.0000 | |
| SRP064894 | PDZD2 | 23037 | RNAseq | -2.5104 | 0.0000 | |
| SRP133303 | PDZD2 | 23037 | RNAseq | -1.5577 | 0.0000 | |
| SRP159526 | PDZD2 | 23037 | RNAseq | -2.6192 | 0.0000 | |
| SRP193095 | PDZD2 | 23037 | RNAseq | -1.7106 | 0.0000 | |
| SRP219564 | PDZD2 | 23037 | RNAseq | -1.3529 | 0.0550 | |
| TCGA | PDZD2 | 23037 | RNAseq | -0.2451 | 0.0549 |
Upregulated datasets: 0; Downregulated datasets: 15.
Survival by PDZD2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PDZD2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PDZD2 | 23037 | 11 | 0 | 19 | |
| GSE20123 | PDZD2 | 23037 | 11 | 0 | 19 | |
| GSE43470 | PDZD2 | 23037 | 15 | 3 | 25 | |
| GSE46452 | PDZD2 | 23037 | 6 | 21 | 32 | |
| GSE47630 | PDZD2 | 23037 | 6 | 12 | 22 | |
| GSE54993 | PDZD2 | 23037 | 5 | 4 | 61 | |
| GSE54994 | PDZD2 | 23037 | 27 | 2 | 24 | |
| GSE60625 | PDZD2 | 23037 | 0 | 0 | 11 | |
| GSE74703 | PDZD2 | 23037 | 12 | 2 | 22 | |
| GSE74704 | PDZD2 | 23037 | 10 | 0 | 10 | |
| TCGA | PDZD2 | 23037 | 51 | 6 | 39 |
Total number of gains: 154; Total number of losses: 50; Total Number of normals: 284.
Somatic mutations of PDZD2:
Generating mutation plots.
Highly correlated genes for PDZD2:
Showing top 20/608 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PDZD2 | FAM163B | 0.781459 | 3 | 0 | 3 |
| PDZD2 | FAM214A | 0.774282 | 5 | 0 | 5 |
| PDZD2 | SPAG17 | 0.771979 | 3 | 0 | 3 |
| PDZD2 | ALDH9A1 | 0.762858 | 10 | 0 | 10 |
| PDZD2 | NICN1 | 0.760299 | 4 | 0 | 3 |
| PDZD2 | UBL3 | 0.752947 | 10 | 0 | 9 |
| PDZD2 | SLC37A1 | 0.747012 | 11 | 0 | 11 |
| PDZD2 | ABCD3 | 0.745375 | 9 | 0 | 9 |
| PDZD2 | EPB41L4A | 0.7449 | 7 | 0 | 7 |
| PDZD2 | PRSS27 | 0.741425 | 6 | 0 | 6 |
| PDZD2 | SNORA68 | 0.737188 | 3 | 0 | 3 |
| PDZD2 | ABLIM3 | 0.73679 | 10 | 0 | 10 |
| PDZD2 | KIAA0232 | 0.72966 | 10 | 0 | 10 |
| PDZD2 | TMOD3 | 0.727627 | 9 | 0 | 9 |
| PDZD2 | BCOR | 0.727113 | 9 | 0 | 9 |
| PDZD2 | UPB1 | 0.725305 | 3 | 0 | 3 |
| PDZD2 | HOPX | 0.724906 | 9 | 0 | 9 |
| PDZD2 | EPS8L2 | 0.722518 | 11 | 0 | 10 |
| PDZD2 | ENDOU | 0.720611 | 9 | 0 | 9 |
| PDZD2 | CLIC3 | 0.718155 | 7 | 0 | 7 |
For details and further investigation, click here
