ABCG5

 

Full name: ATP binding cassette subfamily G member 5 Alias Symbol: STSL
Type: protein-coding gene Cytoband: 2p21
Entrez ID: 64240 HGNC ID: HGNC:13886 Ensembl Gene: ENSG00000138075 OMIM ID: 605459
Drug and gene relationship at DGIdb

 

Expression of ABCG5:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 ABCG5 64240 220383_at 0.0632 0.8360
GSE20347 ABCG5 64240 220383_at -0.1932 0.0029
GSE23400 ABCG5 64240 220383_at -0.1418 0.0001
GSE26886 ABCG5 64240 220383_at 0.0726 0.4825
GSE29001 ABCG5 64240 220383_at -0.2126 0.1974
GSE38129 ABCG5 64240 220383_at -0.1886 0.0027
GSE45670 ABCG5 64240 220383_at 0.0420 0.7988
GSE53622 ABCG5 64240 27041 0.0823 0.4527
GSE53624 ABCG5 64240 27041 0.0786 0.4022
GSE63941 ABCG5 64240 220383_at -0.0224 0.9195
GSE77861 ABCG5 64240 220383_at -0.0968 0.5383
TCGA ABCG5 64240 RNAseq 1.0846 0.0735

Upregulated datasets: 0; Downregulated datasets: 0.  


 

Survival by ABCG5 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of ABCG5:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 ABCG5 64240 10 1 19
GSE20123 ABCG5 64240 9 1 20
GSE43470 ABCG5 64240 4 0 39
GSE46452 ABCG5 64240 1 4 54
GSE47630 ABCG5 64240 7 0 33
GSE54993 ABCG5 64240 0 5 65
GSE54994 ABCG5 64240 10 0 43
GSE60625 ABCG5 64240 0 3 8
GSE74703 ABCG5 64240 4 0 32
GSE74704 ABCG5 64240 9 1 10
TCGA ABCG5 64240 36 2 58

Total number of gains: 90; Total number of losses: 17; Total Number of normals: 381.  


 

Somatic mutations of ABCG5:

 

Generating mutation plots.

 

Highly correlated genes for ABCG5:

 

Showing top 20/194 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
ABCG5DRP20.686806303
ABCG5ACSBG20.655754403
ABCG5VPS530.645087303
ABCG5PDE6A0.643477404
ABCG5THPO0.634069303
ABCG5MEP1B0.628932505
ABCG5CPS1-IT10.626292404
ABCG5USH1C0.619656403
ABCG5CYLC10.618678403
ABCG5GRPR0.61685503
ABCG5CCR40.616226303
ABCG5MC5R0.616129504
ABCG5CEACAM30.607136403
ABCG5ART10.606975403
ABCG5CT550.603008303
ABCG5RARG0.601255504
ABCG5B3GALT10.596956303
ABCG5KCNQ1DN0.594304505
ABCG5SPIN2A0.593162504
ABCG5GYPA0.592354303

For details and further investigation, click here