| Full name: acyl-CoA dehydrogenase very long chain | Alias Symbol: VLCAD|LCACD|ACAD6 | ||
| Type: protein-coding gene | Cytoband: 17p13.1 | ||
| Entrez ID: 37 | HGNC ID: HGNC:92 | Ensembl Gene: ENSG00000072778 | OMIM ID: 609575 |
| Drug and gene relationship at DGIdb | |||
Expression of ACADVL:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ACADVL | 37 | 200710_at | -0.6790 | 0.0642 | |
| GSE20347 | ACADVL | 37 | 200710_at | -1.0549 | 0.0000 | |
| GSE23400 | ACADVL | 37 | 200710_at | -0.7415 | 0.0000 | |
| GSE26886 | ACADVL | 37 | 200710_at | -1.4264 | 0.0000 | |
| GSE29001 | ACADVL | 37 | 200710_at | -1.3262 | 0.0017 | |
| GSE38129 | ACADVL | 37 | 200710_at | -0.8033 | 0.0000 | |
| GSE45670 | ACADVL | 37 | 200710_at | -0.5004 | 0.0092 | |
| GSE53622 | ACADVL | 37 | 111202 | -1.2033 | 0.0000 | |
| GSE53624 | ACADVL | 37 | 111202 | -1.0736 | 0.0000 | |
| GSE63941 | ACADVL | 37 | 200710_at | 0.4674 | 0.2737 | |
| GSE77861 | ACADVL | 37 | 200710_at | -0.4121 | 0.2088 | |
| GSE97050 | ACADVL | 37 | A_23_P207650 | -0.3885 | 0.1584 | |
| SRP007169 | ACADVL | 37 | RNAseq | -1.8528 | 0.0000 | |
| SRP008496 | ACADVL | 37 | RNAseq | -1.7448 | 0.0000 | |
| SRP064894 | ACADVL | 37 | RNAseq | -0.5658 | 0.0007 | |
| SRP133303 | ACADVL | 37 | RNAseq | -1.1985 | 0.0000 | |
| SRP159526 | ACADVL | 37 | RNAseq | -0.7301 | 0.0009 | |
| SRP193095 | ACADVL | 37 | RNAseq | -0.8575 | 0.0000 | |
| SRP219564 | ACADVL | 37 | RNAseq | -0.4360 | 0.2514 | |
| TCGA | ACADVL | 37 | RNAseq | -0.2811 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 8.
Survival by ACADVL expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ACADVL:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ACADVL | 37 | 4 | 2 | 24 | |
| GSE20123 | ACADVL | 37 | 4 | 3 | 23 | |
| GSE43470 | ACADVL | 37 | 1 | 4 | 38 | |
| GSE46452 | ACADVL | 37 | 34 | 1 | 24 | |
| GSE47630 | ACADVL | 37 | 7 | 1 | 32 | |
| GSE54993 | ACADVL | 37 | 4 | 3 | 63 | |
| GSE54994 | ACADVL | 37 | 5 | 8 | 40 | |
| GSE60625 | ACADVL | 37 | 4 | 0 | 7 | |
| GSE74703 | ACADVL | 37 | 1 | 2 | 33 | |
| GSE74704 | ACADVL | 37 | 2 | 1 | 17 | |
| TCGA | ACADVL | 37 | 17 | 21 | 58 |
Total number of gains: 83; Total number of losses: 46; Total Number of normals: 359.
Somatic mutations of ACADVL:
Generating mutation plots.
Highly correlated genes for ACADVL:
Showing top 20/1576 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ACADVL | CA13 | 0.818957 | 3 | 0 | 3 |
| ACADVL | CCDC7 | 0.812099 | 4 | 0 | 4 |
| ACADVL | CASC3 | 0.808715 | 3 | 0 | 3 |
| ACADVL | SLC10A5 | 0.800885 | 3 | 0 | 3 |
| ACADVL | SMURF1 | 0.794486 | 3 | 0 | 3 |
| ACADVL | GALNT11 | 0.786666 | 3 | 0 | 3 |
| ACADVL | CPEB4 | 0.77104 | 6 | 0 | 6 |
| ACADVL | FCHO2 | 0.770525 | 6 | 0 | 6 |
| ACADVL | VSIG2 | 0.763886 | 5 | 0 | 5 |
| ACADVL | NUCB2 | 0.763626 | 10 | 0 | 10 |
| ACADVL | SLC9A9 | 0.76328 | 5 | 0 | 5 |
| ACADVL | SAMD5 | 0.76277 | 6 | 0 | 6 |
| ACADVL | KLHL9 | 0.758598 | 3 | 0 | 3 |
| ACADVL | TPCN1 | 0.754935 | 11 | 0 | 11 |
| ACADVL | NAGK | 0.751692 | 11 | 0 | 10 |
| ACADVL | RMND5B | 0.748285 | 12 | 0 | 11 |
| ACADVL | BNIPL | 0.748004 | 5 | 0 | 5 |
| ACADVL | FBXO8 | 0.747997 | 5 | 0 | 5 |
| ACADVL | MTIF3 | 0.744998 | 5 | 0 | 5 |
| ACADVL | MIEF2 | 0.744159 | 5 | 0 | 5 |
For details and further investigation, click here
