| Full name: BCL2 interacting protein like | Alias Symbol: BNIPl-1|BNIPL-2|PP753|BNIP-S|BNIP-Salpha|BNIP-Sbeta | ||
| Type: protein-coding gene | Cytoband: 1q21.3 | ||
| Entrez ID: 149428 | HGNC ID: HGNC:16976 | Ensembl Gene: ENSG00000163141 | OMIM ID: 611275 |
| Drug and gene relationship at DGIdb | |||
Expression of BNIPL:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | BNIPL | 149428 | 1553072_at | -1.9587 | 0.0902 | |
| GSE26886 | BNIPL | 149428 | 1553072_at | -2.6702 | 0.0000 | |
| GSE45670 | BNIPL | 149428 | 1553072_at | -1.3191 | 0.0003 | |
| GSE53622 | BNIPL | 149428 | 150492 | -2.8643 | 0.0000 | |
| GSE53624 | BNIPL | 149428 | 75141 | -3.4151 | 0.0000 | |
| GSE63941 | BNIPL | 149428 | 1553072_at | 0.1611 | 0.7817 | |
| GSE77861 | BNIPL | 149428 | 1553072_at | -1.0632 | 0.0224 | |
| GSE97050 | BNIPL | 149428 | A_24_P85850 | -1.5617 | 0.1403 | |
| SRP007169 | BNIPL | 149428 | RNAseq | -4.1272 | 0.0000 | |
| SRP008496 | BNIPL | 149428 | RNAseq | -3.8212 | 0.0000 | |
| SRP064894 | BNIPL | 149428 | RNAseq | -3.9838 | 0.0000 | |
| SRP133303 | BNIPL | 149428 | RNAseq | -3.0622 | 0.0000 | |
| SRP159526 | BNIPL | 149428 | RNAseq | -3.0766 | 0.0000 | |
| SRP193095 | BNIPL | 149428 | RNAseq | -3.2660 | 0.0000 | |
| SRP219564 | BNIPL | 149428 | RNAseq | -4.0504 | 0.0001 | |
| TCGA | BNIPL | 149428 | RNAseq | 0.8706 | 0.0114 |
Upregulated datasets: 0; Downregulated datasets: 12.
Survival by BNIPL expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of BNIPL:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | BNIPL | 149428 | 14 | 0 | 16 | |
| GSE20123 | BNIPL | 149428 | 14 | 0 | 16 | |
| GSE43470 | BNIPL | 149428 | 6 | 1 | 36 | |
| GSE46452 | BNIPL | 149428 | 2 | 1 | 56 | |
| GSE47630 | BNIPL | 149428 | 14 | 0 | 26 | |
| GSE54993 | BNIPL | 149428 | 0 | 4 | 66 | |
| GSE54994 | BNIPL | 149428 | 15 | 0 | 38 | |
| GSE60625 | BNIPL | 149428 | 0 | 0 | 11 | |
| GSE74703 | BNIPL | 149428 | 6 | 1 | 29 | |
| GSE74704 | BNIPL | 149428 | 7 | 0 | 13 | |
| TCGA | BNIPL | 149428 | 37 | 2 | 57 |
Total number of gains: 115; Total number of losses: 9; Total Number of normals: 364.
Somatic mutations of BNIPL:
Generating mutation plots.
Highly correlated genes for BNIPL:
Showing top 20/1632 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| BNIPL | CYSRT1 | 0.888478 | 6 | 0 | 6 |
| BNIPL | ENDOU | 0.874569 | 7 | 0 | 7 |
| BNIPL | VSIG10L | 0.872604 | 7 | 0 | 7 |
| BNIPL | PADI1 | 0.863646 | 4 | 0 | 4 |
| BNIPL | MXD1 | 0.862673 | 7 | 0 | 7 |
| BNIPL | ZNF185 | 0.85897 | 8 | 0 | 8 |
| BNIPL | IL36A | 0.858825 | 7 | 0 | 7 |
| BNIPL | A2ML1 | 0.855828 | 8 | 0 | 8 |
| BNIPL | GYS2 | 0.85575 | 6 | 0 | 6 |
| BNIPL | PSCA | 0.85547 | 4 | 0 | 4 |
| BNIPL | SFTA2 | 0.852449 | 4 | 0 | 4 |
| BNIPL | PPL | 0.852394 | 8 | 0 | 8 |
| BNIPL | GDPD3 | 0.849275 | 8 | 0 | 8 |
| BNIPL | EVPL | 0.844067 | 8 | 0 | 8 |
| BNIPL | UPK1A | 0.842912 | 7 | 0 | 7 |
| BNIPL | RAET1E | 0.842793 | 7 | 0 | 7 |
| BNIPL | EPGN | 0.842645 | 3 | 0 | 3 |
| BNIPL | EPS8L1 | 0.842214 | 8 | 0 | 8 |
| BNIPL | TMOD3 | 0.84034 | 7 | 0 | 7 |
| BNIPL | LRP10 | 0.839366 | 6 | 0 | 6 |
For details and further investigation, click here
